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Opeaka's main ingredient is Ketoconazole, which is used topically for topical treatment of fungal infections. So how does Opeaka work, how to use it and what to note when using it? Find out through the article below.1. What is Opeaka?
Opeaka drug has the main ingredient is Ketoconazole 2%, is made in the form of 10g topical tube.Topical creams containing Ketoconazole usually have a rapid effect on itching caused by ringworm and yeast infections, which is often associated with the presence of the fungus Malassezia spp.
Ketoconazole, a synthetic imidazol dioxolane derivative, has potent antifungal activity against ringworms such as Trichophyton spp., Epidermophyton floccosum and Microsporum spp., against yeasts, including Malassezia spp. and Candida spp. Through the mechanism of inhibiting ergosterol biosynthesis in fungi, the effect changes the structure of other lipid components in the membrane.
2. Indications and contraindications of Opeaka
Indications: Opeaka is indicated for use in the following cases:Used topically to treat fungal infections of the skin such as fungal infections of the trunk, groin, hands and feet caused by fungi such as Trichophyton spp. , Microsporon spp and Epidermophyton spp. Opeaka 2% is also indicated for the treatment of candidiasis including vulvovaginitis, vitiligo and seborrheic dermatitis. Contraindications: Patients with known hypersensitivity to the active substance ketoconazole or to any of the ingredients of Opeaka.
3. Dosage and how to use Opeaka
How to use: Opeaka drug is used externally, used to apply on the skin, should clean hands before and after applying the drug, the damaged skin area should be cleaned before applying the medicine.Dosage: Ketoconazole cream is for adults only.
Tinea pedis: Apply 2% ketoconazole cream to the infected skin twice daily. The usual duration of treatment for mild fungal infections is 1 week. For more severe fungal infections (including plantar or bilateral fungal infections) treatment should be continued for a few days after all signs and symptoms have disappeared to prevent recurrence. For other fungal infections: Apply ketoconazole 2% cream to the affected area once or twice daily, depending on the severity of the fungal infection. Treatment should be continued for a few days after the person has not had all the signs and symptoms. The usual duration of treatment for tinea versicolor is 2 - 3 weeks, for fungus in the stem is 3 - 4 weeks. If no clinical improvement is noted after 4 weeks of drug use. The patient's general hygiene practices should be monitored to control sources of infection or re-infection. Note that seborrheic dermatitis is often chronic and recurrent is very high.
For children: There are limited data on the use of the drug, so the use of ketoconazole 2% cream in pediatric patients is not recommended.
4. Undesirable effects of the drug Opeaka
Some reported side effects of Opeaka topical include:Common: Skin and subcutaneous tissue disorders, skin burning sensation; erythema, pruritus at the application site Uncommon: Hypersensitivity reactions; bullous rash, contact dermatitis, skin rash, exfoliative, rough skin; bleeding, malaise, feeling of dryness, dermatitis, irritation, paresthesias, drug site reactions; get angry. Inform your doctor about any unwanted effects you experience while using Opeaka topical.
5. Notes when using Opeaka
Opeaka is a prescription medication, used only when indicated in cases of fungal infections. Tell your doctor about any allergies or other medical conditions you have before taking it. Take only as directed by your doctor and avoid taking larger doses than prescribed. If long-term treatment is required, before taking Opeaka, liver function tests should be performed and during treatment at least once every 1 or 2 months, especially in patients patients are taking other drugs with strong liver toxicity. When liver function test results are significantly increased, or liver function changes are persistent, worsen, or are accompanied by other manifestations of liver dysfunction, the drug should be discontinued. Opeaka 2% cream should not be used in the eyes, if it accidentally gets into the eyes, wash immediately with clean water within 15 minutes. If discomfort persists, consult a specialist. If Opeaka is combined with topical corticosteroids, in order to prevent recurrence of the disease after long-term discontinuation of topical corticosteroid therapy, it is recommended to continue using topical corticosteroids in the morning and to use Opeaka 2% cream. in the evening. Then gradually discontinue topical corticosteroid therapy over a period of 2 to 3 weeks. Pregnancy: There are no adequate and well-controlled studies of Opeaka in pregnant women. No plasma concentrations of ketoconazole were detected following topical application of ketoconazole 2% cream in the skin of non-pregnant subjects. There is no known risk associated with the use of ketoconazole 2% cream in pregnant women, but should be used only when clearly needed. Lactation: No plasma concentrations of ketoconazole have been detected following topical application of ketoconazole 2% cream in the skin of non-pregnant subjects. There is no known risk associated with the use of ketoconazole 2% cream in breast-feeding. But caution should be exercised when taking Opeaka. Overdose: Applying too much Opeaka to the skin can cause erythema, edema, and burning sensation, which usually subside and disappear when the drug is stopped. Swallowing in the mouth: If Opeaka is swallowed by mistake, the patient should be given supportive measures and symptomatic treatment. Drug interactions: Using Opeaka topically, there are no studies on interactions with other drugs. Storage: Keep Opeaka in an airtight container, close the lid after use and avoid direct sunlight. Keep medicine out of reach of children. Hopefully, with the above information about the drug, you know what Opeaka is and how to use it. You should not arbitrarily abuse the drug to avoid the risk of harming the body.Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.