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Ogrel Plus is used in the primary prevention of thromboembolic disorders such as myocardial infarction, stroke and peripheral arterial disease. In addition, the drug is also used in some other cases as prescribed by the doctor to achieve the best effect.1. What is Ogrel Plus? Specify how?
Ogrel Plus is a product of Bosch Pharmaceutical Company (PVT) Ltd. The drug contains the main ingredients are Clopidogrel 75ml, Aspirin 75mg and excipients just enough.
This is a combination drug, indicated in the treatment of acute coronary syndromes in patients who have previously used Aspirin and Clopidogrel, specifically:
Use of the drug with unstable angina or Non-ST-segment elevation myocardial infarction helps effectively prevent thromboembolic disorders such as myocardial infarction and stroke. Support the treatment of acute coronary syndrome for patients who have undergone vascular reconstruction surgery or have never performed. Use for patients with myocardial infarction with ST-segment elevation to effectively prevent thrombotic diseases.
2. Contraindications to the drug Ogrel Plus
Basically Ogrel Plus works as above, in addition, some contraindications to Ogrel Plus include:
People with a history of hypersensitivity to Clopidogrel, Aspirin and non-steroidal anti-inflammatory drugs (asthmatic symptoms appear). , rhinitis or urticaria) immediately after taking the drug. People who have had stomach bleeding recently. The patient is suffering from severe liver and kidney failure. People with signs of bleeding such as peptic ulcer or intracranial hemorrhage, have a bleeding disorder such as hemophilia. Breastfeeding women and children under 16 years of age absolutely do not use Ogrel Plus.
3. Usage and dosage of Ogrel Plus
Ogrel Plus is a drug used orally with reference doses as follows:
Prevention of ischemia (due to myocardial infarction, cerebrovascular accident, coronary artery disease...): Taken with dose 1 tablet x 1 time/day. Patients with acute coronary syndrome: Use an attack dose of 4 tablets/day, maintenance dose of 1 tablet/day.
4. Side effects of drugs
During the use of Ogrel Plus, some common side effects include:
Common side effects: Bleeding, headache, dizziness, indigestion, abdominal pain, diarrhea. Rare side effects: Stomach and duodenal ulcers, gastritis, vomiting, nausea, flatulence, constipation. Very rare side effects: Thrombocytopenia bleeding, hallucinations, taste disturbances, vasculitis, hypotension, bronchospasm, interstitial pneumonia. In addition, patients may also have pancreatitis, colitis, and stomatitis, acute liver failure, hepatitis, arthralgia, myalgia, angioedema, bullous dermatitis,... Basically, the disease Patients should be warned in advance about the signs and symptoms of side effects and what to do if they occur.
5. Interaction with Ogrel Plus
Ogrel Plus can interact with some drugs leading to reduced effects or cause unwanted side effects such as:
Do not use concomitantly with Warfarin because it will increase the risk of bleeding. It reduces the effects of gout medications such as probenecid and sulphinpyrazole. Do not combine the drug with non-steroidal anti-inflammatory drugs and glucocorticoids. When Ogrel Plus is co-administered with diuretics, the risk of fluid retention and the risk of decreased renal function should be carefully considered.
6. Some notes when using Ogrel Plus medicine
In order to use Ogrel Plus safely and effectively, some notes you need to pay attention to include:
Use filtered water when taking the medicine, during the time of taking the drug, stay away from alcohol, beer and other drinks that contain alcohol. contain other stimulants to ensure the drug works best. Because the literature on the use of Ogrel Plus in patients with severe liver disease is limited, extreme caution should be exercised when administering the drug to these patients. Patients undergoing surgery should discontinue Ogrel Plus approximately 7 days prior to surgery. There are currently no clinical data on pregnant women, so it is best not to use the drug during this period. Overdosage can lead to prolonged bleeding time and associated bleeding complications. In case of drug overdose, hemodialysis and peritoneal dialysis can significantly reduce the amount of drug. Therefore, in patients with renal failure or life-threatening toxicity, dialysis is often recommended. If you miss a dose, skip it and take your next dose as usual. Ogrel Plus is indicated for storage in a cool, dry place, below 30°C, protected from light. The use of the drug should be strictly according to the instructions of the specialist. Above is important information about Ogrel Plus that readers can refer to. Because this is a prescription drug, you must not use it on your own, follow the instructions and dosage of your doctor to ensure its effectiveness and safety for your health.
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