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Atorvastatin is a widely used active ingredient in cases where strict control of blood cholesterol levels is required. Atorvastatin is the active ingredient of Normelip 20mg. So what should be noted when using Normelip 20mg product?
1. What is Normelip 20mg?
Normelip 20mg is a product of Square Pharmaceuticals Ltd (Bangladesh) with the active ingredient Atorvastatin 20mg.Normelip 20mg product is prepared in the form of film-coated tablets for oral use, each box includes 2 blisters x 10 tablets.
2. Indications and contraindications of Normelip 20mg
2.1. Indications Indication of the drug Normelip 20mg in the following cases:
Normelip 20mg is indicated mainly for the purpose of reducing the concentration of total blood cholesterol, LDL-cholesterol, apolipoprotein B and triglycerides, and at the same time supporting increasing HDL (a type of good cholesterol) levels in patients diagnosed with primary hypercholesterolemia; Normelip 20mg is also indicated for the treatment of beta-lipoproteinemia in patients who have not responded adequately to a controlled diet; Normelip 20mg is also used in the treatment of homozygous familial hypercholesterolemia when dietary control of total and LDL cholesterol cannot be achieved. 2.2. Contraindications Normelip 20mg is contraindicated in the following cases:
Patients who are allergic to Atorvastatin and HMG-CoA reductase inhibitors (also known as statins); Patients with advanced liver disease or unexplained elevations of liver enzymes; Normelip 20mg should not be used in pregnant and lactating patients.
3. Dosage of Normelip 20mg
Normelip 20mg can be taken at any time of the day and can be taken without regard to meals.
The recommended dose of Normelip 20mg is as follows:
Hypercholesterolemia (heterozygous familial and non-familial) and mixed dyslipidemia: The recommended starting dose is 10-20 mg (1 to 2 mg). ⁄2 to 1 Normelip 20mg tablet), taken 1 time per day. In cases where a significant reduction in LDL levels (greater than 45%) is required, a dose of 40 mg (2 Normelip 20 mg tablets) may be initiated once daily. The therapeutic dose range of Atorvastatin ranges from 10 to 80 mg once daily; After starting treatment and/or after increasing the dose of Normelip 20mg, the patient should be evaluated for blood lipids for a period of 2 to 4 weeks to adjust the dose accordingly; Homozygous Familial Hypercholesterolemia: The recommended dose of Atorvastatin is 10-80 mg/day depending on severity. Note that Normelip 20mg should be combined with other lipid-lowering measures to increase the effectiveness of treatment; Combination therapy: Normelip 20mg can be used in combination with resins to increase the effectiveness of blood cholesterol control; Dosage in patients with renal impairment: No dose adjustment of Normelip 20mg is required in this patient.
4. Side effects of Normelip 20mg
Atorvastatin in general and Normelip 20mg in particular are well tolerated, the side effects, if any, are only mild and transient. Some common side effects when taking Normelip 20mg include: constipation, flatulence, indigestion, abdominal pain, nausea, vomiting, headache or dizziness.
5. Be careful when using Normelip 20mg
Before starting treatment with Normelip 20mg, the doctor should pay attention to exclude the causes of secondary dyslipidemia of the patient, and at the same time, must order a quantitative test of the blood lipid index before starting the treatment. and periodically (with an interval of not less than 4 weeks) during treatment with Normelip 20mg.
During treatment with HMG-CoA reductase inhibitors such as Normelip 20mg, the patient has some conditions such as increased blood creatine kinase, myositis or elevated serum liver enzymes. 3 times the upper limit of normal... the dose should be reduced or treatment discontinued.
Use Normelip 20mg with caution in patients with a history of liver dysfunction or heavy drinkers.
To achieve the highest therapeutic effect, patients need to have a reasonable diet before treatment with Normelip 20mg, then must maintain this regimen throughout the course of taking the drug.
6. Normelip 20mg . Drug Interactions
Anticoagulants or Indandione when combined with Normelip 20mg will increase bleeding time or prothrombin time. Therefore, patients should be closely monitored for prothrombin time if concomitant use of these drugs is required. Cyclosporine, Erythromycin, Gemfibrozil, drugs that suppress the immune system and Niacin when used in combination with Normelip 20mg increase the risk of side effects of myositis, myalgia. Digoxin used in combination with Normelip 20mg may slightly increase digoxin serum concentrations. Normelip medicine 20mg has the main ingredient is Atorvastatin with a strength of 20mg. The drug is used in cases where strict control of blood cholesterol levels is required. Therefore, to ensure the effectiveness and increase the treatment effect, and at the same time avoid unwanted side effects, patients need to carefully read the instructions and consult the doctor, pharmacist for advice.
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