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Nobantalgin drug with main ingredients is Paracetamol, Thiamin nitrate function, Chlorpheniramine maleate is indicated for the treatment of pain relief and hypothermia in cases of patients suffering from: Arthritis pain, headache, fever, cord pain. Nervousness, toothache,... Here are some useful information about Nobantalgin to help patients learn and use the drug safely and effectively.1. What is Nobantalgin?
Nobantalgin is a drug belonging to the group of analgesics, antipyretics, non-Steroid anti-inflammatory drugs, for the treatment of Gout and osteoarthritis. Nobantalgin is manufactured in the form of capsules, packaged in boxes of 10 blisters x 10 capsules.Nobantalgin drug has the main ingredients: Paracetamol 400mg, Thiamin nitrate 50mg, Chlorpheniramine maleate 2mg and other excipients just enough for 1 tablet.
2. What are the uses of Nobantalgin?
Cases where patients are indicated when using Nobantalgin to treat diseases such as:
Pain relief for patients with: Arthritis, myositis. Headache, neuralgia, toothache, back pain caused by kidney stones or gallstones. Pain in otorhinolaryngology. Treatment to cool down when the patient has: cold, fever, runny nose, flu, pneumonia, tuberculosis.
3. Dosage - How to take Nobantalgin
3.1. How to use Nobantalgin Nobantalgin drug is prepared in the form of tablets, to be tolerated in the body by oral route, according to tablets.
3.2. Dosage Nobantalgin drug dosage depends on each subject and the course of the disease, there will be an appropriate dose. Below is the dosage of Nobantalgin for reference as follows:
For adults:
Dosage of Nobantalgin is 0.3g - 0.5g/day, divided into 1 to 3 times a day by taking Nobantalgin. The maximum dose of Nobantalgin is 1 time / 1g in 1 day, 24 hours / 3g. Use Nobantalgin in batches, avoid prolonged use. For children from 6 to 15 years old: Nobantalgin dosage is 0.1g - 0.2g/day, divided into 1-3 times a day.
Note: Patients do not arbitrarily calculate, apply or change the dose. Users need to pay attention to apply the exact dose of Nobantalgin 500mg as stated in the drug instruction leaflet or as directed by a doctor or pharmacist.
4. Contraindications of Nobantalgin
Nobantalgin drug is not used in the following cases:
Patients with hypersensitivity or history of allergy to pyrazolone and salicylates derivatives (especially Amidopyrin and Noramidopyrin). Nobantalgin should not be used in children under 15 years of age. Nobantalgin should not be used in patients with the following accompanying pathological symptoms: Patients with a history of agranulocytosis regardless of cause, liver porphyria, multiple anemia or heart disease, lung, kidney or liver disease. Patients with deficiency of Glucose - 6 - Phosphate dehydrogenase, having an asthma attack of grade W 4 have just enough 1 tablet, have symptoms of prostate enlargement, have narrow-angle glaucoma, peptic ulcer disease, pyloric - duodenal obstruction. Nobantalgin should not be used by women who are breastfeeding. Do not use Nobantalgin in patients who are taking Monoamine oxidase inhibitors within 14 days.
5. Precautions when using Nobantalgin
Here are some notes for patients before taking Nobantalgin for treatment:
Nobantalgin can cause agranulocytosis which is very dangerous. If you use Nobantalgin and have a fever, sore throat or mouth sores, you must immediately stop taking the drug and check the blood chart urgently, if agranulocytosis has to go to the hospital for emergency and timely treatment. Nobantalgin should be used with caution in patients with liver-renal failure, cardiac arrhythmia, acute myocardial infarction, coronary insufficiency, hyperthyroidism, chronic bronchitis, toxic colonic hypertrophy, paralytic ileus, glaucoma. closed angle, prostatic urethral disorders. Nobantalgin causes agranulocytosis (10% of deaths). Nobantalgin can cause drowsiness, so it should be used with caution when driving a train and operating machinery. Avoid or limit alcohol while taking Nobantalgin. Use Nobantalgin with caution in patients with pre-existing anemia; people with chronic lung disease, shortness of breath or difficulty breathing; patients with myasthenia gravis; patients with glaucoma; elderly (>60 years old). Pregnancy: Nobantalgin should be used during pregnancy only when clearly needed. Taking Nobantalgin during the third trimester of pregnancy can lead to serious reactions (such as seizures) in the newborn baby. Lactation: The active ingredient chlorpheniramine in the drug can be excreted in breast milk and inhibits lactation. Therefore, consideration should be given to either not breastfeeding or not taking Nobantalgin, depending on how necessary the drug is to the mother.
6. Undesirable effects when taking Nobantalgin thuốc
During the use of Nobantalgin, patients may experience some unwanted side effects such as:
Dry mouth, drowsiness, dysregulation, urinary retention. Skin rash, nausea/vomiting, pancytopenia, neutropenia, leukopenia, anemia, nephrotoxicity with long-term use. Hypersensitivity reactions have rarely occurred. Patients should inform the doctor about the undesirable effects encountered when using Nobantalgin.
7. Nobantalgin drug interactions with other drugs
The following are some reported Nobantalgin drug interactions such as:
Long-term use of paracetamol in high doses may slightly increase the anticoagulant effect of coumarin and indandion derivatives. Attention should be paid to the potential for severe hypothermia in patients receiving concomitant antipyretic therapy and phenothiazines. Patients who use alcohol too much and for a long time can increase the risk of paracetamol causing liver toxicity. Anticonvulsants such as phenytoin, barbiturates... can induce enzymes in the liver microsomes and may increase the hepatotoxicity of paracetamol. Monoamine oxidase inhibitors prolong and potentiate the anticholinergic effects of antihistamines. Ethanol or other sedative-hypnotics in combination with Nobantalgin may potentiate the CNS depressant effects of chlorpheniramine. Clopheniramine in combination with phenytoin may inhibit phenytoin metabolism. Note: Nobantalgin is prescribed by a doctor, patients should not use Nobantalgin without indication for use.
