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Nivalin is a drug used to treat Alzheimer's disease or peripheral neuropathy associated with movement disorders. So what does Nivalin do?
1. Effects of Nivalin
Before learning about the use of Nivalin 5mg tablets, let's understand what Nivalin is? Nivalin 5mg medicine contains the active ingredient galantamine hydrobromide 5mg and other excipients such as lactose monohydrate, talc, magnesium stearate, microcrystalline cellulose, calcium hydrogenphosphate dihydrate which are effective in the treatment of mild to moderate dementia in Alzheimer's disease. . In addition, Nivalin is also used to treat peripheral neuropathy associated with movement disorders such as:
polyneuropathy radiculopathy neuritis Polyneuritis In addition, the drug Nivalin 5mg is also used in the treatment of motor paralysis after spinal cord disease, loss of mobility after stroke or muscle weakness, muscular dystrophy.
In addition, some other effects of the drug are not listed on the approved drug label, but in some cases the doctor may prescribe the use of Nivalin. Therefore, before taking the medicine, consult your doctor.
2. How to use Nivalin
Nivalin 5mg is in the form of film coated tablets. Dosage will be based on the condition and age of the patient.
Peripheral neuropathy associated with movement disorders, the dose is 10-40mg and divided into 2-4 times/day. Motor paralysis after spinal cord disease, the dose is 10-40mg and divided into oral doses 2-4 times/day 2-4 times/day Muscle weakness or dystrophy: dose from 10-40mg divided oral dose into 2-4 times/day For Alzheimer's disease: Adults daily dose from 5mg orally 2 times/day and maintained for 4 weeks then dose may be increased to 10mg twice daily. For patients with moderate hepatic impairment, the dose is from 15mg/day and not for patients with severe hepatic impairment. Patients with renal impairment should not take more than 15mg/day and should not be used for treatment in patients with severe renal impairment. The duration of treatment depends on the patient's condition and tolerability and can vary from several weeks to several years. In the event of side effects, the dose should be reduced or treatment should be stopped for 2-3 days and then restarted at a lower dose. However, in case of stopping treatment with Nivalin for a long time, when restarting the patient should start from the lowest dose, then gradually increase to reach the optimal maintenance dose.
Patients can take the drug with or without food, before or after eating. However, to reduce stomach irritation you can take it with food and need to swallow the tablet whole with a full glass of water, do not chew or break the tablet.
To use the drug safely, take Nivalin 5mg exactly as directed by your doctor, do not use more, smaller or longer than prescribed. Patients absolutely do not abuse the drug for too long for a long time. This does not make the patient's condition better, but also increases the risk of unwanted effects.
3. Undesirable effects when using the drug Nivalin
Nivalin 5mg medicine can cause some unwanted and common side effects that can be mentioned as:
Nausea, vomiting Diarrhea Loss of appetite Weight loss Abdominal pain Indigestion Slow heart rate Postural hypotension Heart failure Bloc Atrioventricular palpitations Atrial fibrillation Syncope Indigestion Gastroenteritis Gastrointestinal bleeding Before prescribing medicine, doctors always consider the benefits and effectiveness of Nivalin. When using Nivalin can still occur unwanted effects. Therefore, when there are unusual symptoms, especially when a severe allergic reaction occurs, the patient should immediately notify the doctor or nurse for immediate medical intervention.
4. Some notes when using Nivalin
Some notes when using Nivalin include:
History of allergy to Nivalin hypersensitivity reaction to any other allergy. Nivalin may contain inactive ingredients and could cause an allergic reaction or other serious problems. Report any medications you are taking including prescription and nonprescription drugs, herbal and dietary supplements, foods, dyes or preservatives. Contraindicated to use Nivalin in patients with severe liver failure, severe renal failure (creatinine clearance <9ml/min) Do not use the drug for children Nivalin can cause urinary retention. On the nervous system: Nivalin has the potential to increase the risk of convulsions, secondary epilepsy. Caution should be exercised in patients with prior asthma or chronic obstructive pulmonary disease, with mild to moderate hepatic or renal impairment. people who are taking galantamine because it may increase the effects of drugs that cause muscle relaxants. There are not enough studies to evaluate the use of Nivalin in pregnancy in pregnant women, however, animal studies have shown that galantamine slows fetal growth and new animals. birth, so still need to be careful while using the drug during pregnancy. Note, Nivalin can cause bradycardia, atrioventricular block. Therefore, special caution should be exercised in patients with supraventricular arrhythmias and those taking drugs that slow the heart rate. In addition, the drug Nivalin 5mg increases gastric secretion. Therefore, it should be used with caution in high-risk subjects such as people who have ever had peptic ulcers, are taking non-steroidal anti-inflammatory drugs.
5. Drug interactions
Some drugs that can interact with Nivalin include:
Succinylcholine-type muscle relaxants used in surgery. Anticholinergics Cholinergic stimulants (cholinergic agonists or cholinergic inhibitors): Synergistic effects when used concurrently. Non-steroidal anti-inflammatory drugs (NSAIDs) Digoxin and beta-blockers Cimetindin Paroxetin Amitriptyline Fluoxetin Fluvoxamine Quinidine
6. How to store Nivalin
Store Nivalin with film-coated tablets at room temperature below 30 degrees Celsius, protect from light and avoid humid places. Do not store Nivalin in a humid place or in the freezer and keep it away from heat and open flames. Different medicines will have different storage methods, so read the Nivalin 5mg storage instructions carefully on the packaging, or ask your pharmacist. Keep Nivalin out of the reach of children and family pets. When the medicine has expired or is damaged and cannot be used anymore, dispose of it and dispose of it properly. Do not arbitrarily dispose of Nivalin into the environment such as water pipes or toilets unless requested. Please consult your waste disposal company or pharmacist on how to safely dispose of Nivalin 5mg to help protect the environment.
In short, to use drugs safely, patients need to comply with the doctor's prescriptions. In some cases of side effects, please notify your doctor for timely treatment.
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