This is an automatically translated article.
New drug AMERHINO contains the main ingredient is Phenylephrin HCl 5mg; Loratadine 5 mg other active ingredients. The drug is applied in the treatment of symptoms of nasal congestion, sneezing ... and many other uses. Read the article below to learn about the benefits of this drug.
1. What are the uses of New AMERHINO?
Phenylephrine hydrochloride is a sympathomimetic drug that acts directly on adrenergic receptors (œ--adrenergic) to decongest the nose. Phenylephrine hydrochloride has low bioavailability when administered orally due to uneven absorption from the gastrointestinal tract. The drug undergoes first-pass metabolism in the intestines and liver by monoamine oxidase.Besides, the component Loratadin is a tricyclic antihistamine, has a selective antagonistic effect on peripheral H1 receptors and has no inhibitory effect on the central nervous system. Loratadine is effective in alleviating symptoms of allergic rhinitis, pruritus and urticaria due to histamine release. Loratadin
belongs to the class of histamine H receptor antagonists; 2nd generation (no sedation). Loratadine is rapidly absorbed from the gastrointestinal tract after oral administration. Peak plasma concentrations are reached in about 1 hour. Taking the drug with meals prolongs the time to reach peak plasma concentrations while increasing bioavailability. Loratadine is extensively metabolised. The main metabolite has potent antihistamine activity. The mean
half-life of Loratadine ranges from 8.4 to 28 hours. 98% Loratadine is bound to plasma proteins.
The combination of the two main ingredients above helps the drug to be effective in the treatment of nasal congestion, sneezing, runny nose, itchy nose, itchy eyes, watery eyes caused by allergic rhinitis.
On the other hand, the drug is not indicated in cases where the patient is sensitive to the components of the drug and antidepressants. Children under 2 years of age are also contraindicated to use the drug.
2. Dosage and how to use New AMERHINO
2.1. Dosage The drug is in the form of film-coated tablets, which should be taken orally. Patients can take the drug with or without food, before or after eating. However, to reduce stomach irritation you can take it with food and need to swallow the tablet whole with a full glass of water, do not chew or break the tablet.
2.2. Dosage Recommended dosage for adults and children over 12 years: 1 tablet a day. The recommended dosage for children 2 years to 12 years of age is weight-adjusted. Specifically: >30 kg (body weight): 1 tablet a day. <30kg (body weight): 1⁄2 tablets a day. 2.3. Overdose/missed dose management To use the medicine safely, take New AMERHINO exactly as directed by your doctor, do not use more, smaller or longer than prescribed. Use New AMERHINO regularly to get the most benefit from it and can stop taking it if any new signs of abnormality appear or the condition does not improve after 7 days. Patients absolutely do not abuse the drug for too long for a long time. This does not make the patient's condition better, but also increases the risk of unwanted effects.
In case of missed dose, the patient should take it again as soon as possible. However, if it is close to the time of your next dose, skip the missed dose and continue taking or injecting the medicine as scheduled.
There have been some cases of overdose of New AMERHINO with typical symptoms such as: Drowsiness, headache, drop in blood pressure, tachycardia, arrhythmia, extrapyramidal and movement disorders, tremor. or spasticity, restlessness, muscle spasms, changes in breathing and heart rate, nausea, vomiting... For these cases, the patient is indicated to treat each symptom.
3. Side effects of the drug New AMERHINO
Some of the side effects of New AMERHINO are as follows: Dizziness, insomnia, nervousness, headache, increase or decrease in blood pressure, palpitations, tachycardia, nausea, vomiting, dry mouth, sore throat, weak...
Inform the doctor about the unwanted effects encountered when using the drug.
4. New AMERHINO drug interactions
There have been recorded interactions between New AMERHINO and some other drugs such as:
New AMERHINO when used with antidepressants (amitriptyline, imipramine, sertraline, moclobemide), sympathomimetic drug groups (epinephrine) and anesthetic drugs (halothan) will increase toxicity. Pretreatment with adrenergic blocking agents (eg, phentolamine, phenothiazines, propranolol) will reduce the effectiveness of Phenylephrine. Cold, cough and allergy medications also have the potential to interact with New AMERHINO. Therefore, patients should consult their doctor if they are taking these drugs together.
5. Precautions while using New AMERHINO
With caution in patients with impaired liver or kidney function including patients taking drugs that affect the liver. Pregnancy and breast-feeding: Consult your doctor if you are pregnant or breast-feeding before using this medicine. Different medicines will have different storage methods, so read the New AMERHINO storage instructions carefully on the packaging, or ask your pharmacist.
