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Nevirapine Stada 200mg is a drug belonging to the group of anti-parasitic, anti-infective, anti-viral, anti-fungal drugs used to treat HIV-infected patients. Let's find out the information about the drug Nevirapine Stada 200 mg in the following article.1. What is Nevirapine Stada 200 mg?
What is Nevirapine Stada 200 mg? Nevirapine Stada 200 mg belongs to the group of antiretroviral drugs, indicated for use in combination with other antiretroviral drugs in the treatment of HIV-1 infected patients; prevention of transmission from HIV-infected mothers to their children.Nevirapine Stada 200 mg is made in the form of tablets, with the packing specification is a box of 3 blisters, 6 blisters x 10 tablets, or a box of 1 bottle of 30 tablets, 60 tablets. Each tablet contains 200 mg.
Nevirapine Stada 200mg is composed of the main active ingredient, Nevirapine 200mg and excipients in sufficient strength.
2. What are the uses of Nevirapine Stada 200 mg?
The main active ingredient Nevirapine contained in the drug is one of the substances that inhibit the HIV non-nucleoside reverse transcriptase (NNRTI) enzyme - 1. Helps to inhibit and inhibit the growth and replication of the HIV virus in HIV-1. different stages in the life of the virus.Indications of the drug Nevirapine Stada 200 mg:
Nevirapine is indicated for the treatment of HIV-1 infection, but must be combined with at least 2 antiretroviral drugs. Nevirapine is indicated for use in pregnant women infected with HIV-1 at the time of labor if they have not been previously treated with antiretroviral agents. Reduces the risk of mother-to-child transmission of HIV-1. It is recommended to use in combination with other antiretroviral drugs for pregnant women before giving birth to minimize the possibility of transmission.
3. How to use Nevirapine Stada 200 mg:
3.1. How to use Nevirapine Stada 200 mg For the drug Nevirapine Stada 200 mg, users use it orally. You need to prepare a full glass of water, drink exactly as prescribed and the dose prescribed by your doctor.3.2. Dosage of Nevirapine Stada 200 mg Adults: It is recommended to take 1 tablet per day for the first 14 days (the correct dose should be taken initially to help reduce the frequency of skin rashes), then increase to 2 tablets per day. Note to use in combination with at least 2 other antiretroviral drugs.
Children aged 2 months to 8 years: The recommended dose is 4mg/kg, orally once a day for the first 14 days, then (if there is no rash) increase to 7mg/kg, orally 2 times /day. Children aged 8 years and older: dose is 4mg/kg, orally once a day for the first 14 days, then 4mg/kg, twice a day. For pregnant women: A single 200 mg dose of Nevirapine should be administered prior to labor in female patients for whom highly active antiretroviral therapy is not indicated or available. Combined oral administration with a single dose of zidovudine and lamivudine to protect the parturition. For neonates: A single oral dose of 2mg/kg is administered within 72 hours of birth. The total daily dose should not exceed 400 mg, applicable to all patients. 3.3. Missing dose: If the patient forgets to take the medicine within 8 hours, the missed dose should be taken as soon as possible. If it is more than 8 hours, the patient takes the next dose and skips the missed dose at the time prescribed by the doctor. Do not take 2 doses at the same time.
Overdosage: There is no documented antidote to nevirapine in case of overdose. Cases of nevirapine overdose have been reported with patients taking 800-1,800mg/day for 15 days. Patients with overdose have signs of edema, erythema nodosum, fever, headache, insomnia, nausea, pulmonary infiltrates, rash, dizziness, vomiting, increased transaminases, weight loss. These symptoms will be relieved when the drug is stopped.
In case of emergency or overdose with dangerous manifestations, the patient should immediately notify the nearest local health facility for timely handling.
3.4. Contraindications Nevirapine Stada 200mg Drug Nevirapine Stada 200mg is contraindicated in the following cases:
People with a history of hypersensitivity to any ingredient of the drug, or especially allergic to the active ingredient Nevirapine. The patient had to be permanently discontinued because of severe rash with systemic symptoms, hypersensitivity reactions or clinical hepatitis due to nevirapine. Patients with severe hepatic impairment or patients with ALT or AST levels greater than 5 times the normal value (ULN). Patients had a history of AST or ALT elevations above 5 times the normal value (ULN) during treatment with nevirapine and a rapid reappearance of liver function abnormalities upon re-administration of nevirapine.
4. Notes when taking Nevirapine Stada 200 mg
Caution when using Nevirapine Stada 200 mg:Care should be taken to use the drug in patients with impaired liver and kidney function. The necessary clinical chemistry tests of liver function should be performed periodically during treatment with Nevirapine. Care should be taken when operating vehicles or machinery. Pregnant women: Note not for pregnant women in the first 3 months of pregnancy. Breastfeeding: HIV-infected mothers should not breastfeed if they are taking nevirapine to avoid the risk of HIV transmission after delivery. Read the instructions for use carefully and follow exactly as directed by your doctor. If any skin reaction is detected, the drug should be discontinued immediately and the treating physician reported because patients taking nevirapine or any antiretroviral drug are very susceptible to opportunistic infections. Side effects when using Nevirapine Stada 200 mg When using Nevirapine Stada 200mg, patients may experience unwanted side effects such as:
Common, ADR > 1/100
Body as a whole: Fatigue, pain head, sleepy. Skin: Rash usually appears in the first 5 weeks of taking the drug, itchy skin. Gastrointestinal: Abdominal discomfort, abdominal pain, nausea, diarrhea. Uncommon, 1/1000 < ADR < 1/100
Hypersensitivity reactions: Itching with fever, myalgia, arthralgia, swollen lymph nodes. Kidney: Renal dysfunction. Rarely, 1/10000 < ADR < 1/1000
Anaphylaxis possibly life-threatening: Angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis, Lyell's syndrome. Severe hepatotoxicity: Hepatic necrosis. When experiencing any side effects of the drug, the patient should stop using it and promptly notify the doctor or go to the nearest medical facility.
Drug Interactions Nevirapine Stada 200 mg Nevirapine STADA 200mg is mainly composed of the ingredient Nevirapine, which is a substance that can reduce the concentration of some HIV enzyme inhibitors such as saquinavir when used in combination with together. However, these drugs do not affect the effects of Nevirapine Stada 200mg, so no dose adjustment may be necessary when taken together. Methadone concentrations may be decreased when Nevirapine Stada 200mg is co-administered. Concomitant use of Nevirapine and Ketoconazole is not recommended, as a decrease in its plasma concentration may reduce its potency. Note that the interaction of Nevirapine Stada 200mg with Prednisolone may increase the incidence of rash during the first 6 weeks of nevirapine administration. Storage of Nevirapine Stada 200 mg Keep the medicine in an airtight container. Keep the medicine in a dry place, the temperature does not exceed 30°C. Do not expose the medicine to direct sunlight. Keep out of reach of children This is the complete information about Nevirapine Stada 200 mg . This drug is indicated for the treatment of HIV-infected patients. Patients are absolutely not allowed to buy drugs for treatment without their doctor's instructions.
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