This is an automatically translated article.
Nergamdicin is an effective treatment for urinary tract infections, in the form of film-coated tablets and administered orally. However, the drug is not suitable for people with renal failure, hematopoietic disorders, epilepsy, increased intracranial pressure and children under 3 months of age.1. What is Nergamdicin?
Nergamdicin 500mg drug main ingredient is Nalidixic acid - antibiotic with bactericidal effect with broad antibacterial spectrum. From here, the use of the drug Nergamdicin is highly appreciated by users, especially promoting its effect on most gram-negative anaerobic bacteria such as E. Coli proteus, Klebsiella, Enterobacter, helping to eliminate easily.However, Nalidixic acid has no effect on intestinal anaerobic bacteria, thereby ensuring not to upset the balance of intestinal flora when taking the drug orally.
2. Indications and contraindications Nergamdicin
2.1. Indications Nergamdicin is indicated for use in the treatment of the following problems:
Acute lower urinary tract infections or uncomplicated recurrent infections. In addition, bacillus dysentery, diarrhea caused by infection. Treatment of urinary tract and genital tract infections caused by gram-negative bacteria including cystitis, pyelonephritis, urethritis... Treatment of gastrointestinal infections caused by negative bacteria including inflammatory diseases stomach, enteritis... 2.2. Contraindications Nergamdicin 500mg is contraindicated in the following subjects:
People who are allergic or have a history of allergy to Nalidixic acid or other quinolone derivatives. Patient has or has a history of convulsions or epilepsy. Contraindicated in children under 3 months of age. People with kidney failure, disorders of blood formation, increased cranial pressure should also not use Nergamdicin. People with impaired liver function or G6PD deficiency, because of the potential risk of drug accumulation in the body, leading to drug poisoning.
3. Dosage and how to use Nergamdicin
3.1. Dosage Adults: Use Nergamdicin at a dose of 2 tablets x 2-4 times/day, for at least 7 days. If the disease is not cured and treatment needs to be continued for more than 2 weeks, the dose should be reduced by half.
Children from 3 months to 12 years old: Use at a dose of 50-55 mg/kg/day divided into 4 oral doses. If treatment is prolonged, the dose should be reduced to 30-33 mg/kg/day.
In case of creatinine clearance above 20 ml/min, normal dose can be used.
In the case of creatinine clearance less than 20 ml/min, the dose should be considered to be reduced to 2 g.
3.2. How to use Nergamdicin drug is prepared in the form of long film-coated tablets, used orally. Should take the drug before meals, use water when drinking.
You should take the tablet whole, do not break, crush or chew the tablet when taking it. Take the medicine at the same time every day to get the best treatment effect.
4. Common side effects of Nergamdicin
During the use of Nergamdicin drug to treat the disease, patients may experience some unwanted reactions as follows:
Systemic reactions include feeling headache, dizziness, dizziness, visual disturbances . Gastrointestinal reactions include nausea, vomiting or diarrhea. Common skin reactions include blistering of the skin on sun exposure during and after drug treatment. In addition, some uncommon side effects when using Nergamdicin include:
Central nervous system reactions including increased pressure in the skull. Allergic reactions include urticaria, pruritus, and photosensitization. Rare side effects include:
Nergamdicin may affect the central nervous system such as confusion, hallucinations, nightmares. Effects on blood sugar such as thrombocytopenia, leukopenia, eosinophilia, anemia. Rarely, anaphylactic reactions, angioedema, pain in the joints. When experiencing the side effects of the drug, the patient just needs to rest or stop taking the drug, they will soon disappear. In case of severe allergic reaction, you need to immediately notify the treating doctor for the best support.
5. Interactions with other drugs
Some drugs have interactions when used in combination with Nergamdicin, including:
Concomitant use with nalidixic acid will cause the concentration of Theophyllin in the blood plasma to increase. Concomitant use with nalidixic acid may increase caffeine concentrations by affecting caffeine metabolism. Concomitant use with nalidixic acid enhances the effect of warfarin and its derivatives. Concomitant use with nalidixic acid also increases plasma concentrations of cyclosporin. Reduced effect when combined with Nitrofurantoin. The use of gastric antacids containing magnesium, calcium, sucralfate and divalent or trivalent cations such as zinc and iron can reduce the absorption of components present in Nergamdicin, leading to a decrease in the concentration of nalidixic acid in the urine. . This will reduce the antibacterial effect of the drug.
6. Some notes when using Nergamdicin
When using the drug Nergamdicin in the treatment of disease, you should note the following points:
Take the drug regularly every day, on time for the best treatment effect. Store the medicine at room temperature, the location for the medicine should be dry, avoid mold and moisture. Keep out of reach of children, do not let children play with the medicine, even with the packaging. Before using the drug, it is necessary to carefully check the color and taste of the drug. Absolutely do not drink when Nergamdicin has a strange smell or the tablet is watery, sticky to the surface. Tablets with broken or chipped edges should not be used to ensure safety. Be careful when using the drug for pregnant and lactating women, especially in the first and third trimesters of pregnancy. Do not use Nergamdicin for people who need to operate machinery and drive vehicles because it can cause dizziness, dizziness, headache, fatigue, visual disturbances, nausea... Above is some information about Nergamdicin drug. 500mg that you can refer to. Remember to carefully read the instructions for use of the drug as well as follow the instructions of the doctor, pharmacist to get the best treatment effect.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
