This is an automatically translated article.
Nemipam is a prescription drug, with a strong analgesic effect, the drug is indicated in cases of pain relief after surgery, pain due to cancer.... To ensure the effectiveness of using Nemipam, the patient also needs to follow the instructions. Follow the instructions of a specialist, and refer to more information about the uses of Nemipam in the article below.
1. What are the uses of Nemipam?
1.1. What is Nemipam? Nemipam belongs to the group of analgesics, antipyretics, non-steroid anti-inflammatory drugs, drugs for the treatment of Gout and osteoarthritis.
The drug is prepared in the form of a blister tablet of 10 tablets, a box of 1 blister, with the main ingredient being Nefopam Hydrochloride 30 mg.
Nemipam is recommended for use by adults, and children 12 years of age and older.
1.2. What are the uses of Nemipam? The active ingredient Nefopam is classified as one of the most powerful and fast acting pain relievers. Nefopam has a completely different effect from other centrally acting analgesics such as codeine, morphine, pentazocine and propoxyphene. At the same time, nefopam has also been shown to not cause respiratory depression.
Nemipam is prescribed by doctors for the following cases:
Need to relieve acute and chronic pain, including toothache, musculoskeletal pain, postoperative pain, acute pain caused by trauma and pain caused by cancer. Contraindications:
Patients who are allergic to the main active ingredient Nefopam or any of the excipients of Nemipam. Patients with a history of seizures Patients with angle-closure glaucoma Patients taking a mono-amine-oxidase (MAO) inhibitor. Children under 12 years of age Group of pregnant and lactating women.
2. How to use Nemipam
2.1. How to take Nemipam Nemipam is taken orally, to avoid stomach irritation, patients should take the drug after eating. Take Nemipam tablets whole with a glass of filtered or boiled water, do not crush or break them, or mix them with any solution or mixture. Use strictly according to the doctor's prescription, do not arbitrarily calculate the dose, do not take more than the prescribed dose, it may increase side effects or be less, leading to the concentration of Nemipam in the blood not being enough to promote the full effect. 2.2. Dosage of the drug Nemipam Adults: 1 tablet each time x 3 to 4 times/day. If pain is severe, a single dose of 90 mg can be used. Maximum level: 300 mg of Nemipam in 24 hours. Elderly: Elderly subjects may require a dose reduction due to their slower metabolism. In particular, it is recommended that the starting dose not exceed 1 tablet x 3 times daily. Because there have been few reports of CNS adverse effects with nefopam and some cases of hallucinations or confusion. Renal Impairment: During treatment with Nemipam, patients with end-stage renal disease may experience increased peak serum concentrations. To avoid unwanted effects, the manufacturer recommends reducing the daily dose for the elderly and patients with end-stage renal failure. Treatment when missed dose: To achieve the best pain-relieving effect, the patient should try not to forget the medicine, if he forgets the medicine, take it as soon as he remembers, but it is necessary to have a snack before taking the medicine. Especially with indications for taking several times a day, the time between 2 doses should be at least 6 hours apart. If it is almost time for your next dose, do not take the dose you missed and wait until the scheduled time for the next dose. Remember the time to take your next dose will apply from the time you took the missed dose. Do not take a double dose of Nemipam to make up for a missed dose.
Treatment of overdose: Clinical symptoms of nefopam overdose cause toxicity mainly with the nervous system (hallucinations, convulsions, coma and agitation) and cardiovascular system (hyperactive circulation, heart rate). fast).
Management: Quickly take supportive measures and remove the ingested drug by gastric lavage or induce vomiting with Ipecacuanha Syrup. Taking activated charcoal can help prevent the absorption of the drug into the digestive system. Seizures and hallucinations should be controlled (diazepam may be given intravenously). Beta-adrenergic blockers can help control cardiovascular complications.
3. Notes when using Nemipam
The side effects of Nemipam may depend on the side effects of drugs with anticholinergic or sympathomimetic activity when taken together. Hepatic and renal failure may interfere with the metabolism and excretion of the active substance nefopam. Nemipam should be used with caution in patients with existing or at risk of urinary retention. Rarely, a temporary pink coloration of the urine has occurred. The active substance Nefopam in Nemipam is excreted in breast milk. The drug concentration in the plasma of the breastfed infant is approximately the same as that in the maternal plasma. Because of the potential for side effects, breastfeeding should be discontinued during treatment with Nefopam. Do not use Nefopam when the expiry date indicated on the package has passed, the tablet changes color, is watery, has signs of mold or the blister pack is unsealed.
4. Nemipam side effects
Nemipam side effects that may occur during use are as follows:
Immune system: Allergic reactions, anaphylactic reactions Psychiatric: Anxiety, convulsions, confused state, hallucinations , insomnia Nervous system: Dizziness, syncope, dizziness, dysarthria, tremor, drowsiness, headache, coma Eyes: blurred vision Heart: Palpitations, tachycardia, low blood pressure Digestion: Nausea , vomiting, dry mouth, gastrointestinal disturbances (including abdominal pain and diarrhea) Skin and tissues: Angioedema, sweating Kidneys and urinary tract: Urinary retention
5. Nemipam drug interactions
Caution should be exercised when using Nemipam concomitantly with tricyclic antidepressants.
Note: Nefopam may interfere with some biochemical tests that screen for benzodiazepines and opioids. These tests for benzodiazepines and opioids may give false-positive results in patients receiving preparations containing nefopam.
6. How to store Nemipam
The shelf life of Nemipam is 36 months from the date of manufacture. Store medicinal products at a suitable room temperature from 15 to 25 degrees Celsius, do not expose the drug to direct sunlight, locations with high heat sources such as next to televisions, heaters or refrigerators that are easy to conduct. to the pill being modified. Avoid storing medicine in humid places such as bathrooms, or places with high humidity below 70% that easily breed mold. Medicines should be kept out of reach of small children. Nemipam is a prescription drug, with a strong analgesic effect, the drug is indicated in cases of pain relief after surgery, pain due to cancer.... To ensure the effectiveness of using Nemipam, patients also need to follow it. instructions of a specialist.
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