This is an automatically translated article.
Movinavir is made in the form of hard capsules, with the main ingredient being the active ingredient Molnupiravir. The drug is used in the treatment of mild and moderate COVID-19 in adults with the disease, who are at risk of worsening the disease.
1. What is the use of Movinavir?
Movinavir 200mg drug has the main active ingredient Molnupiravir (200mg content) and excipients. This is a newly licensed drug for the treatment of people with COVID-19.
Molnupiravir has the ability to inhibit the replication and replication of many virus strains, including SARS-CoV-2. Active ingredient Molnupiravir creates viral gene mutations in 2 stages:
Stage 1: Thanks to the body's metabolism, Molnupiravir is activated. This active substance penetrates into cells, converted into blocks with a structure similar to RNA; Stage 2: These blocks penetrate the viral genetic material structures, creating new viruses but contain many errors, making the virus unable to replicate anymore. Indications for use of Movinavir:
Used to treat mild to moderate COVID-19 in adults who are positive for COVID-19 and have at least 1 risk factor for severe disease progression (when present). directed by Doctor). Contraindications to using Movinavir:
Patients with hypersensitivity to the active ingredient Molnupiravir or to the excipients of the drug; Patients under 18 years old (due to the risk of affecting the bone and cartilage development of children).
2. Instructions on how to take Movinavir
Usage: Orally. Patients should take the medicine with a full glass of water, with or without food. Patients should be advised not to open, crush or chew the tablet.
Dosage:
Dosage in adults:
Recommended dose: Oral dose of 800mg Movinavir every 12 hours for 5 days; The safety and effectiveness of the drug when used for more than 5 days have not been established; Patients with COVID-19 should take Movinavir as soon as possible after being diagnosed with the virus, within 5 days of first symptom onset; Limit drug use: Do not take the drug for more than 5 days in a row; Do not use drugs for pre-exposure prophylaxis; Do not use the drug for the initial treatment of patients requiring hospitalization due to COVID-19 because the benefit of the drug has not been documented at the beginning of use in this group of patients. Patients who were already taking Movinavir before being admitted to the hospital can continue taking the drug for the full course of treatment. Dosage in other subjects:
Children: The safety and effectiveness of Movinavir in children have not been established. Therefore, it is not recommended to use the drug for this subject; Elderly: No dose adjustment is required; Patients with renal failure : No dose adjustment is required; Patients with hepatic impairment: No dose adjustment is required. Overdose: There have been no documented cases of an overdose of Movinavir. If the drug overdose, the patient should be hospitalized immediately for timely emergency treatment. Treatment is usually the application of general supportive measures, including monitoring the patient's clinical condition.
Missed dose: If you miss a dose of Movinavir within 10 hours of the time you need to take it, the patient should take it as soon as possible, continue to take the next dose as usual. If you miss a dose more than 10 hours, the patient should not take the missed dose again, but need to take the next dose as scheduled. Patients should not take a double dose to make up for a missed dose.
3. Side effects of Movinavir
When using Movinavir, patients may experience side effects such as: Insomnia, headache, dizziness, nausea, hangover, irritability, diarrhea,... If you notice any effects If any side effects are suspected to be due to the drug, the patient should contact the doctor for monitoring and treatment.
4. Notes when taking Movinavir
Some notes for patients to remember when using Movinavir:
Movinavir is not recommended for pregnant women; Movinavir is not recommended for people under 18 years of age; Do not use Movinavir for pre-/post-exposure prophylaxis of COVID-19; Do not use Movinavir for the initial treatment of patients requiring hospitalization due to COVID-19; Patients are not allowed to arbitrarily buy Movinavir for treatment without a doctor's prescription. It is recommended to buy drugs at reputable pharmacies, not to buy drugs at stores with unclear addresses, do not ensure product origin; Take Movinavir as prescribed by the doctor, do not arbitrarily increase/decrease the dose or prolong the duration of the drug (because the safety and effectiveness of the drug has not been determined for a long time); Check the expiration date, carefully read the instructions for use, do not use Movinavir if there are signs of damage or poor quality; Use caution when using Movinavir in patients with liver failure, kidney failure, immunodeficiency,... These subjects need to be monitored for their health, especially when they have COVID-19; Movinavir may affect low-risk men's sperm quality. Therefore, to ensure safety, within 3 months after taking the drug, the patient should apply contraceptive measures; Patients should keep a comfortable mind, should supplement with adequate nutrients during the course of taking the drug to quickly recover from the disease; Patients should use contraception for 5 days after taking Movinavir. Breastfeeding should not be breast-feeding during the period of taking the drug and for 5 days after the last dose.
5. Interactions of Movinavir
Drug interactions when using 2 or more drugs at the same time may cause some effect on the action of the drug or cause side effects. There are no clinical reports on drug interactions Movinavir with other drugs. Therefore, patients should inform their doctors about the drugs and functional foods they are using for advice and guidance on safe and effective drug use.
In the process of taking Movinavir, it is necessary for the patient to strictly follow all the instructions of the doctor. If the condition worsens, side effects appear, the patient should immediately notify the doctor for timely intervention and treatment. At the same time, patients should maintain a comfortable and optimistic mentality, drink lots of water, and supplement with nutrition to soon defeat COVID-19.
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