Uses of Migomik

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1. What is Migomik?

Migomik is a new drug with the main ingredient is Dihydroergotamine mesylate used to treat a number of diseases such as: hypotension, migraine, orthostatic circulatory disorders with symptoms of fatigue, dizziness, tinnitus , languid,....
Pine Migomik is prepared in the form of long tablets.
In addition to the main ingredient is Dihydroergotamine mesylate 3mg, the drug also contains excipients: dioxyde de titane, macrogol 400, glycerol, purified water, propylene glycol, gelatine, ascorbic acid, iron oxide III.
This is a prescription drug, so patients need to be careful and use it exactly as prescribed by the doctor.

2. Effects and indications for taking Migomik

2.1 The effect of the drug Migomik In the drug Migomik contains the main active ingredient Dihydroergotamine - this is an alkaloid found in ergot mushrooms.
The mechanism is to act on both alpha - adrenergic and serotonergic receptors, which both helps to stimulate at therapeutic doses the carotid system in the outer layer of the brain, and inhibits the blocking of receptors, especially when using high doses. Reduces orthostatic hypotension: Dihydroergotamine has a selective effect on causing the vessels containing veins and venules to contract without affecting the arteries and arterioles. This helps the blood vessels to redistribute blood volume, reducing the accumulation of blood in the veins due to imbalance. Improve Migraine Condition: When the active ingredient Dihydroergotamine enters the body, the first thing is to help the body compensate for the lack of Serotonin in the blood plasma. When Serotonin is overproduced, it will counteract the loss of tone of the vascular system outside the skull, thereby preventing migraine recurrence. Therefore, oral medicine Migomik is well researched and applied to treat orthostatic hypotension and migraine.
2.2 Indications for use From the above effects, Migomik is indicated for treatment in the following cases:
Symptomatic treatment of orthostatic circulatory disorders and hypotension due to posture changes. Treatment of headaches, migraines. Treatment of migraine due to vasomotor imbalance.

3. Dosage and how to use Migomik

Migomik is a medicine and is prescribed by a specialist. Therefore, to avoid affecting the patient's health, it is necessary to take the right dose and at the right time.
3.1 Dosage Vasomotor headache: Usually, the doctor will prescribe 1mg intramuscular injection once and again after 1 hour until the symptoms are relieved, but not more than 3mg/day. Treatment of postural hypotension: 1 tablet/time x 3 times/day. 3.2 How to take Migomik Migomik is taken by drinking directly with filtered water, to ensure effective absorption, the best time to drink is before meals. After taking the drug, the patient should rest for a while and avoid vigorous exercise.
Note: For vasomotor migraine, as soon as symptoms appear, the drug must be taken as soon as possible to be effective and shorten the treatment time. The above information is for reference only. The correct dose depends on the condition of the disease and will be prescribed by the doctor accordingly.

4. Contraindications to taking Migomik

Migomik is contraindicated in the following cases:
People who are allergic to the active ingredient Dihydroergotamine Mesylate or other excipients of the drug. People with certain diseases such as: patients with uncontrolled hypertension, coronary artery disease, shock, severe liver/kidney failure, sepsis, vascular surgery, peripheral artery disease. Patient is taking other vasopressors. Pregnant and lactating women.

5. Side effects when using Migomik

During the use of Migomik, patients may experience some side effects as follows:
Common side effects: Vomiting, headache, nausea, body aches, leg cramps,... Effects Uncommon side effects: Dizziness, profuse sweating, anxiety, nervousness, abdominal pain, frequent bowel movements, increased blood pressure, vasospasm, rash, paresthesia, redness, difficulty breathing, .. Effects Rare side effects: myocardial infarction, stroke,... Usually the mild side effects will go away after a few days, but the patient is not so subjective. Take the initiative to contact your doctor immediately if you have any unusual symptoms or doubt about the drug.

6. Interactions of drugs Migomik

Drug interactions when using Migomik 3mg with other drugs is inevitable. Therefore, in order to avoid unwanted interactions, patients should be careful not to use them together with the following drugs:
Vasopressors: May cause blood pressure to rise suddenly. Nicotine: Increased risk of ischemia. Beta-blockers: Causes severe vasoconstriction and reduces blood flow. Macrolide antibiotics: Greater risk of side effects. Methysergid: Causes arteries to increase the risk of constriction. In addition to the drug interactions mentioned above, during the use of drugs, there are many other drug interactions that can occur. Therefore, in order for the treatment process to be safe and effective, patients should provide their doctors or specialists with the drugs they are taking for advice on appropriate use.

7. Notes when using Migomik

During the use of Migomik, patients should note:
Vasoconstriction, angina pectoris may occur during treatment with Migomik. Therefore, if there are abnormal signs of vasoconstriction such as loss of sensation, muscle pain, cold feet and legs, pale skin, angina, cyanosis of the hands and feet, or ischemia, the patient should stop taking the drug and go to the hospital. medical facilities for examination and treatment. Migomik is only effective for vasomotor migraines, not for normal headache relief. If there are symptoms such as itching, throbbing pain in the fingers and toes, slow heart rate, swelling, edema, .... it is not subjective but immediately notify the doctor for instructions and indications. Although only a small amount of Migomik crosses the placenta and may not harm an unborn baby. However, it can constrict uterine blood vessels, reducing blood flow to the uterus. Therefore, absolutely do not prescribe this drug to pregnant women. Active ingredient Dihydroergotamine is partially excreted in breast milk, so when breastfed babies may experience side effects such as diarrhea, abdominal pain, fussiness, weak pulse, irregular heartbeat, low blood pressure, .. .. Therefore, this subject is also not prescribed medication. Migomik has many side effects such as nausea, abdominal pain, headache, low blood pressure, itching,... Therefore, do not use before and are active in labor, driving or moving. Patients only take Migomik when prescribed by a doctor.

8. Treatment of forgetting or overdose of Migomik

Overdose: If after taking an overdose, the body appears some symptoms such as: sharp pain, blue-violet skin, convulsions, loss of sensation, delirium, blood pressure disturbances, slow heart rate, shortness of breath, confusion, coma... Stop using and apply a hot towel at the painful location and take the patient to the emergency room immediately. Missed dose: If you forget to take a dose, the patient should take it as soon as he remembers, if the time to take the supplement is far from the time of the next dose. Otherwise, if it is close or coincident, skip the missed dose and take the next dose as usual. Be careful not to overdo the dose. In summary, Migomik is a prescription drug that belongs to the group of psychotropic drugs, known for its effects on migraine headaches, lowering blood pressure caused by sudden changes in position, dizziness, orthostatic circulatory disorders and headache diseases. To ensure effective treatment and avoid unwanted side effects, patients need to take the medicine exactly as directed by the doctor and pharmacist.
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