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Microstat suppositories are made in the form of vaginal tablets, containing the main ingredients Miconazole Nitrate, Tinidazole and Neomycin. Microstat is indicated in cases of acute and chronic vaginal infections, prevention of recurrent vaginal yeast infections, trichomoniasis, Candida infections,...
1. The effect of the drug Microstat
Microstat is a combination of 3 active ingredients: Miconazole + Neomycin + Tinidazole to treat gynecological inflammatory diseases caused by bacteria, fungi and protozoa.
Miconazole, Neomycin and Tinidazole act directly into the vaginal tract to clear up infections. Miconazole Nitrate is a potent antifungal (including Candida spp.) and anti-bacterial (including Gram-positive microorganisms such as Streptococcus spp. and Staphylococcus spp.).
Neomycin is a broad spectrum antibiotic. Highly susceptible Gram-negative species are E. coli, Enterobacter aerogenes, Klebsiella pneumoniae, and Proteus vulgaris. Inhibited Gram-positive microorganisms include Staph. aureus and E. faecalis. M. tuberculosis is also sensitive to neomycin.
Tinidazole - a 5-nitroimidazole that works by damaging DNA strands or inhibiting their synthesis, more active and longer lasting than metronidazole. Active against protozoa (Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia) and nearly anaerobic bacteria (Bacteroides fragilis, Bacteroides melaninogenicus, Bacteroides spp., Clostridium spp., Eubacterium spp, Fusobacterium spp, Peptococcus spp) .
2. Indication of Microstat
Microstat suppositories are indicated in the following cases:
Acute and chronic vaginal infections, abnormal vaginal discharge. Uterine infection. Vaginitis caused by Candida , Trichomonas infection or another agent. Vulvaritis (appearance of burning pain in the vagina). Prophylaxis of vaginal yeast infections.
3. Dosage and how to use vaginal suppositories
How to use:
Because the drug is prepared in the form of a tablet placed in the vagina, there are notes on how to use it to promote the good effect of the drug. Putting the medicine in the evening before going to bed is the right time. Wash your hands and private area clean before placing, pay attention not to douche deep into the vagina, then dry with a clean dry towel. Dip the tablet for about 2-3 seconds in cooled boiled water and quickly remove the tablet to avoid crushing the tablet for a long time. To make it easier to put the medicine, put the medicine in the supine position, with the knees bent, place the tablet deep into the vagina and rest for 15 minutes so that the medicine dissolves and does not fall out. Dosage:
The dose below is for reference only, depending on your medical condition and doctor's prescription.
Use in the evening before going to bed dose 1 tablet / time. Use continuously for 7-10 days.
4. Pay attention when forgetting and overdosing
When you miss a dose:
Because the medicine is given in the evening, if you miss a dose, you can skip the missed dose. There is no need to take a double dose to make up for a missed dose. In case of overdose:
Symptoms: the body appears in shock and is accompanied by serious symptoms such as rash, itching, convulsions, hypotension, dizziness, shortness of breath, breathing disturbances, seizures, ... Treatment: Stop using the drug and immediately go to the nearest medical center for treatment. It is advisable to bring used medicine with you so that the doctor can quickly determine the cause.
5.Undesirable effects when using Microstat
During the course of taking the drug, patients may experience some side effects such as:
Common: Redness, burning of the vagina, itching in the private area, nausea and vomiting, headache, diarrhea. Rare: vaginal bleeding, blood disorders, dizziness, dizziness, seizures, convulsions, blisters, urticaria, glossitis, fatigue, dry mouth, fatigue, body weakness, loss of appetite , burning sensation. The above are some possible side effects, if there are other unusual signs, contact your treating doctor for further advice.
6. Microstat drug interactions
Microstat interacts with some of the following drugs:
Phenobarbital, rifampin, phenytoin, and fosphenytoin (a precursor to phenytoin), which can accelerate the elimination of tinidazole, reducing tinidazole plasma concentrations. Cimetidine and ketoconazole, which may prolong the half-life and decrease the plasma clearance of tinidazole, increase the plasma concentration of tinidazole. Phenobarbital reduces the effect of Tinidazole. Oral anticoagulants: Severe bleeding with oral miconazole, oral gel due to inhibition of warfarin metabolism and increased circulating free form in the blood. There is a possibility of eczema due to allergic contact. This occurs most often in cases of prolonged treatment. Eczema can spread to areas far from treated areas. For neomycin, cross-allergenicity with aminoside antibiotics is possible.
7. Notes when using Microstat suppositories
The duration of treatment must be limited due to the risk of drug resistance and the risk of superinfection. Exercise caution during pregnancy, especially in the first trimester, only on the advice of a doctor. This is consistent with general guidelines for drug use. Lactation: Tinidazole is excreted in breast milk after 72 hours. Use as directed by your doctor. Other special note
Prescription drugs are only used when prescribed by a doctor. Do not have sex while using the drug because it can cause bleeding in the vagina or surrounding area. Inform your doctor about your history of drug allergies and current medications. Above is all the important information about Microstat suppositories. When you intend to use it, you should actively learn about the drug and follow the instructions of a specialist doctor.
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