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Mexams 10 is a medicine that works to prevent the risk of acute asthma attacks, reduce the severity of asthma attacks and reduce the symptoms of allergic rhinitis.
1. Uses of Mexams 10
Mexams 10 medicine has the main ingredient is Montelukast 10mg.
The cysteinyl leukotrienes (LTC4, LTD, LTE4) are potent inflammatory agents secreted by a variety of cells, including mast cells and eosinophils. These important mediators involved in asthma development bind to cysteinyl leukotriene (CysLT1) receptors and induce inflammatory effects.
CysLT type 1 (CysLT1) receptors are found inside the human airways, including on airway smooth muscle cells and macrophages, in other proinflammatory cells. CysLT has been found to correlate with the physiology of asthma and allergic rhinitis. When cysteinyl leukotriene receptor mediators cause effects such as:
In asthma some effects on the airways, such as bronchoconstriction, affect mucus secretion, capillary permeability and replenishment eosinophils. In allergic rhinitis can cause allergic rhinitis symptoms. Montelukast is a compound that binds with high affinity and selectively to type 1 cysteinyl leukotriene receptors, from which Montelukast inhibits the physiological activity of LTD4 at the cysteinyl leukotriene receptor. Helps relieve symptoms of allergic rhinitis and reduce asthma exacerbations.
2. Uses of Mexams 10
Indications:
Mexams is used to prevent inflammation caused by allergic respiratory diseases and is indicated for use in the following cases:
Prophylaxis and treatment of chronic asthma, reducing the severity of asthma attacks. Prophylaxis of symptoms of exercise-induced bronchospasm. Helps relieve symptoms of allergic rhinitis (seasonal allergic rhinitis or persistent allergic rhinitis). Contraindications:
Mexams 10 is contraindicated in the following cases:
Patients with hypersensitivity to Montelukast or to any of its ingredients. Do not give this medicine to children under 6 years old, due to the inappropriate dosage.
3. Usage and dosage of Mexams 10
How to use: Mexams 10 is taken orally, before going to bed.
Dosage:
For children from 6 to 14 years old: 5mg/time/day in the evening. Patients 15 years and older: Take 10mg/time/day in the evening. Overdose: Manifestations of an overdose of Mexams 10 such as: Abdominal pain, drowsiness, thirst, headache, vomiting and increased agitation. Patients need to stop taking Mexams 10 immediately and go to the nearest medical facility for timely treatment.
4. Side effects of Mexams 10
When using Mexams 10, you may also experience unwanted effects such as:
Common: Hypersensitivity reactions including anaphylaxis, angioedema, skin itching, rash, urticaria, anxiety , hallucinations, somnolence, agitation including aggressive behavior, hyperactivity, insomnia, paresthesia or hypoesthesia, vomiting, nausea, dyspepsia and diarrhea. Uncommon: Increased AST and ALT, arthralgia, myalgia including muscle cramps, increased possibility of bleeding, subcutaneous bleeding, palpitations, edema. Very rare: Hypersensitivity reactions such as eosinophilic infiltration of the liver, convulsions, cholestatic hepatitis. When experiencing side effects of the above drugs or other effects suspected of taking Mexams 10, you need to stop using and notify your doctor or go to the nearest medical facility for timely treatment.
5. Notes when using Mexams 10
The efficacy of oral Mexams 10 in the treatment of acute asthma attacks has not been established. Therefore, oral montelukast should not be used alone for the treatment of acute asthma attacks. The patient should be prescribed the appropriate treatment available. Oral and inhaled corticosteroids should not be abruptly substituted with montelukast-containing drugs. When a dose reduction is desired, it should be reduced slowly and with caution and close clinical monitoring when reducing the dose of corticosteroids. Mexams 10 should not be used as the sole treatment for people with exercise-induced bronchospasm. For patients with symptoms of exercise-induced asthma, regular adherence to treatment with inhaled beta-blockers or as directed by a physician is still required. Agents known to cause allergic reactions should be avoided, to make the drug more effective or to increase the effectiveness of other treatments. Ability to drive and use machines: Because when taking this drug, some unwanted effects may occur such as anxiety, hallucinations, feeling drowsy, agitation. Therefore, if montelukast is prescribed, patients should be careful or if these side effects occur, they should avoid driving and operating machinery. For pregnant and lactating women, use only when absolutely necessary, and should be used with caution. Drug Interactions: Area under the curve with montelukast can be reduced by about 40% in people co-administered with Phenobarbital, no dose adjustment is required for Mexams 10. Some other drugs may cause interactions, you should report them. Talk to your doctor about medications. Avoid using combinations of drugs that can cause interactions to decrease drug effects or increase side effects. Storage: Mexams 10 should be stored in a cool place, away from direct sunlight, at a storage temperature not exceeding 30°C. Above is the information about the drug Mexams 10, you need to take it regularly and maintain it for a long time to increase the effectiveness of the treatment. If there is an abnormality during treatment, you need to report it to your doctor for treatment.
