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Methionine is commonly used in the treatment of Paracetamol overdose. Complying with indications and doses of Methionine will help patients improve treatment efficiency and ensure safety for health.
1. What is Methionine?
Methionine is a pharmaceutical product manufactured by Domesco Medical Import-Export Joint Stock Company, Vietnam. Methionine belongs to the group of emergency and detoxifying drugs with the main ingredient being Methionine 250mg and other excipients. The drug is mainly used to treat paracetamol overdose, thereby preventing liver damage in the absence of Acetylcysteine.
Methionine 250mg is made in the form of tablets and packed in a box of 1 bottle x 150 tablets.
2. Methionine drug use
Effect of medicinal ingredients:
Methionine is an essential amino acid found in the composition of diets and formulations of multi-acid preparations for nourishment. Methionine has the effect of enhancing Glutathione synthesis and it is used as an alternative to Acetylcysteine to treat Paracetamol overdose to prevent liver damage. In addition, Methionine is also used orally to lower urine pH, treat liver dysfunction (or it can be said that Methionine is a liver tonic). Besides, Methionine also has the effect of improving wound healing, treating alcoholism, depression, asthma, allergies, schizophrenia ... Methionine is mainly used to treat cases of the following:
Paracetamol overdose in the absence of Acetylcysteine. In addition, the drug is also used to acidify the urine. Treatment of hepatitis caused by toxic, toxic pregnancy. Treatment of anemia, rashes, cirrhosis, viral hepatitis, jaundice. Methionine 250mg drug is recommended contraindicated in some of the following cases:
People who are allergic to Methionine or one of the other ingredients of the drug. The patient has an acidosis. Severe liver damage.
3. How to use and dose Methionine
Uses of Methionine 250mg will be fully effective if used correctly and in the dosage prescribed by a professional doctor. Below are the usage and dosage that patients can refer to.
How to use:
Methionine 250mg is made in the form of tablets, so it should be taken orally. Patients need to take the drug during or after having a full meal to avoid irritating the stomach. Patients can consult a doctor / pharmacist for advice on the best way to use and carefully read the manufacturer's instructions for use printed on the drug packaging. Reference drug dosage for each purpose and subject is as follows:
Treatment of overdose Paracetamol: It is necessary to treat at least 10-12 hours after taking Paracetamol. Adults and children over 6 years: Oral dose of 2.5g / time, starting after taking an overdose of Paracetamol and 1 time every 4 hours, taking 4 full doses depending on the concentration of Paracetamol in plasma. Children under 6 years: Oral dose of 1g / time, starting after taking an overdose of Paracetamol and taking 4 hours every 4 hours and taking 4 full doses. Note: The above dosage is for reference only, and the specific Methionine dose will depend on the condition and severity of the disease. Therefore, for the best and most appropriate dosage, you should consult a specialist doctor or pharmacist or medical professional.
Handling missed dose, overdose:
In case of missed dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and take the next dose as prescribed. When using high doses of Methionine, there is a risk of increasing blood clots, while taking Methionine in excess, patients may have signs of nausea, vomiting, and irritability. In case of overdose, the patient should wash the stomach and carry out symptomatic and supportive treatment. In case of emergency, it is necessary to take the patient to the nearest medical center and facility for timely examination and treatment.
4. Side effects of drugs
When taking Methionine 250mg, users may experience some undesirable effects such as: Nausea, vomiting, irritability, drowsiness and may cause metabolic acidosis or azotemia in people with kidney failure. .
When experiencing unwanted effects of the drug, the patient should stop taking and notify the doctor or go to the nearest medical center for timely treatment.
5. Drug interactions
Methionine may decrease the effects of Levodopa. Therefore, high doses of methionine should be avoided in patients being treated with levodopa.
To avoid drug interactions that reduce the effectiveness of Methionine, you should inform your doctor about all medications you are taking for advice on the safest and most effective medication.
6. Notes and cautions
When using Methionine, patients need to be careful and pay attention to some of the following issues:
The drug is only used under the guidance and prescription of the doctor. Never increase or decrease the dose of the drug without consulting your doctor. Methionine should be used with caution in people with severe liver disease. Because methionine can make liver damage worse in people who already have liver failure. In patients who already have liver failure or liver damage, methionine can cause progressive liver encephalopathy. Methionine should not be used to treat Paracetamol poisoning if it has been more than 12 hours since the overdose. Methionine can cause drowsiness, so it should be used with caution when driving or operating machinery. There are currently no data on methionine in pregnant and lactating women. Therefore, these subjects need to be very careful when taking Methionine.
7. How to preserve
The drug should be stored in a cool and dry place with a temperature below 30 degrees Celsius, avoiding sunlight to reduce the effectiveness of Methionine. Do not store the medicine in a place with high humidity such as a refrigerator or bathroom. The medicine should be kept out of the reach of small children.
Above is all information about the uses of Methionine as well as how to use, dosage and note when using. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Methionine exactly as directed by your doctor.
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