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Mepragold is indicated to help reduce total cholesterol, LDL cholesterol, triglycerides and apolipoprotein B, increase HDL-cholesterol in patients with primary hypercholesterolemia, blood betalipoprotein disorder,... So what is the use of Mepragold? ?1. What are the effects of Mepragold 20mg?
Mepragold belongs to the group of cardiovascular drugs with the active ingredient atorvastatin in the form of atorvastatin calcium. In particular, atorvastatin is a drug belonging to the group of HMG-CoA reductase inhibitors. This is a cholesterol-lowering drug. Mepragold works by inhibiting cholesterol production in the liver by inhibiting a cholesterol-producing enzyme called HMGCoA reductase. At the same time, reduces the level of total cholesterol as well as LDL cholesterol in the blood (LDL cholesterol is classified as bad cholesterol and plays a major role in coronary heart disease). Lowering your LDL cholesterol levels will slow the progression and possibly even reverse coronary heart disease. Unlike other drugs in this class, atorvastatin may also work to lower blood triglyceride levels. In addition, high blood triglyceride levels are also associated with coronary heart disease.2. Indications and contraindications of Mepragold
2.1 Indications for use of Mepragold Indications for use of Mepragold drug in the following cases:
Reduce total cholesterol, LDL-cholesterol, triglycerides and apolipoprotein V Increase HDL-cholesterol in patients with primary hypercholesterolemia Patients with disorders betalipoproteinemia does not respond adequately to diet. Mepragold is also indicated for the reduction of total cholesterol and LDL-cholesterol in patients with homozygous familial hypercholesterolemia when dietary improvement has not been achieved. Besides the above uses, Mepragold may also be used to treat some other conditions that are not listed above. Therefore, before using the drug, consult your doctor for advice and effective use of the drug.
2.2 Contraindications to the use of Mepragold The use of Mepragold is contraindicated in the following cases:
Patients with hypersensitivity to HMG-CoA reductase inhibitors Patients with progressive liver disease or persistent elevation of serum transaminases without clear cause pregnant women lactating women
3. Usage and dosage of Mepragold 20mg
Mepragold is made in the form of film-coated tablets, so the drug is taken orally. The time to take the drug can be before or after a meal, but the patient does not crush or break it. Dosage of Mepragold drug will depend on the patient's disease status and age such as:
For cases of hypercholesterolemia (heterozygous familial and non-familial) and mixed dyslipidemia In case: the recommended starting dose is 10mg - 20mg, taken once a day. Patients who require a significant reduction in LDL cholesterol (more than 45%) may be initiated at a dose of 40 mg once daily. The interval between therapeutic doses of the drug is 10-80mg once daily. After starting treatment and/or increasing the dose of Mepragold, it is necessary to assess the blood lipids at 2 to 4 weeks and to adjust the dose accordingly. Homozygous familial hypercholesterolemia: use at a dose of 10-80mg/day. In addition, it should be combined with other lipid-lowering measures. Combination therapy: Mepragold can be used in combination with resin to increase the effectiveness of treatment. Dosage in patients with renal impairment does not require dose adjustment. Patients need to use Mepragold regularly to get the most benefit from it. To use it safely, take Mepragold exactly as directed by your doctor, do not use it more often, for less or for longer than prescribed. Do not use the drug for longer than the duration of treatment or increase the dose of the drug arbitrarily. Because this will make the condition worse and increase the risk of unwanted effects.
4. Undesirable effects when using Mepragold 20mg drug
Some unwanted effects that may occur when using Mepragold include:
Constipation Flatulence Indigestion Abdominal pain Nausea, vomiting Headache Dizziness Before prescribing the drug, the doctor always considers the benefits And the effectiveness of Mepragold outweighs the risk of side effects. However, some cases when taking Mepragold can still occur unwanted effects. Therefore, when unusual signs appear after taking the drug, especially when a severe allergic reaction occurs with accompanying signs such as difficulty breathing, increased dizziness, swelling, rash or itching. face, tongue, throat,... In this case, the patient or family member should immediately notify the medical staff so that timely intervention can be made.
5. Some notes when using Mepragold 20mg drug
Some notes when using Mepragold medicine include:
Inform your doctor about a history of allergy to Mepragold or any other allergies. Mepragold may contain ingredients that are inactive and could cause an allergic reaction or other serious problems. Notice what medications you are taking including prescription drugs, over-the-counter medicines, herbal and dietary supplements, dyes or preservatives. Before treatment with Mepragold, care should be taken to rule out secondary causes of dyslipidemia and measure lipid indices. Conduct periodic quantification during the treatment period with an interval of not less than 4 weeks. During treatment with Mepragold with HMG-CoA reductase inhibitors, if creatine kinase is elevated, myositis develops, or liver enzyme levels in the blood are 3 times higher than normal, the dose should be reduced or discontinued. treatment. Use with caution in patients with liver dysfunction or patients who drink a lot of alcohol. Before treatment with Mepragold, the patient should have a reasonable diet, this regimen should be maintained throughout the course of treatment with the drug. If you forget to take a dose, take it again as soon as possible. However, if it is close to the time of the next dose, skip the missed dose and then continue taking it as scheduled. Do not arbitrarily double the dose of the drug compared to the treatment regimen. Using an overdose of Mepragold can cause serious symptoms such as nausea, vomiting, abdominal pain, weakness,...
6. Drug interactions
Drug interactions can decrease the effectiveness of Mepragold, or increase the effect of unwanted effects. Tell your doctor about all other medicines you are taking including vitamins, prescription drugs, over-the-counter medicines, and herbal products. Never stop, start or change the dose of any medicine without your doctor's consent.
Some drugs that can interact with Mepragold include:
Anticoagulants, indandione in combination with Mepragold will increase bleeding time or prothrombin time. Therefore, during treatment, it is necessary to monitor prothrombin time in patients taking in combination with anticoagulants: Cyclosporine, gemfibrozil, erythromycin, immunosuppressants, niacin: combined with Mepragold increases the risk of increased risk. myopathy. Digoxin: if combined with Mepragold causes a slight increase in serum digoxin concentration
7. How to store Mepragold 20mg
Store Mepragold at room temperature, away from light and away from moisture. Do not store Mepragold in a humid place or in the freezer. Different medicines will have different storage methods, so read the Mepragold storage instructions carefully on the packaging, or ask your pharmacist. Keep Mepragold out of the reach of children and family pets. When the medicine has been damaged or has expired, dispose of it properly. Do not arbitrarily dispose of Mepragold in an environment such as a plumbing or toilet unless requested to do so. Please consult your waste management company or pharmacist on how to safely dispose of Mepragold to help protect the environment.
In summary, Mepragold is indicated to help reduce total cholesterol, LDL cholesterol, triglycerides and apolipoprotein B, increase HDL-cholesterol in patients with primary hypercholesterolemia, dysbetalipoproteinemia,... However, Mepragold May cause some unwanted effects and drug interactions, so tell your doctor what medicines you are taking to reduce the risk of side effects and at the same time increase the effectiveness of the treatment process. treat.
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