Uses of Lyrasil 0.3%

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1. What is Lyrasil?

What is Lyrasil? Each 5ml solution of Lyrasil contains 15mg of Tobramycin and excipients just enough. Tobramycin is an aminoglycoside antibiotic obtained from the culture of Streptomyces tenebarius; the drug has a bactericidal effect. Mechanistically, Lyrasil inhibits protein synthesis in susceptible strains of bacteria.
Tobramycin is active against many aerobic Gram-negative bacteria and some aerobic Gram-positive bacteria including: E.coli, Ps.aeruginosa, Enterobacter and Serratia. Tobramycin has good effects on strains of S.flexner, S.typhi, Proteus spp. In addition, Tobramycin is not active against fungi, chlamydia, viruses and most anaerobes.
Tobramycin penetrates very poorly into aqueous humor. Topical amounts of Tobramycin will be removed from the ocular surface over a period of 15 to 30 minutes. Systemic concentrations of Tobramycin remained below detectable levels in humans when treated with Tobramycin 0.3% ophthalmic solution. Indications: Lyrasil is used in the treatment of eye infections caused by strains of bacteria sensitive to Tobramycin such as: lacrimal sac, eyelid inflammation, keratitis, conjunctivitis, corneal ulceration, eyelid acne. .
Contraindications : Do not use Lyrasil 0.3% for patients with hypersensitivity to the drug's components or bacitracin or aminoglycoside antibiotics.

2. Usage and dosage of Lyrasil

How to use : Use Lyrasil by eye drops. Note that each vial should not be used together for many people to avoid infection, and do not use the medicine more than 15 days after the first opening to ensure effective treatment.
Dosage:
For mild and normal cases: Instill 1-2 drops every 4 hours; For severe cases: Instill 2 drops every hour until symptoms improve, then gradually reduce the dose and stop the drug. Overdose and treatment: Keratitis, increased lacrimation and erythema are possible symptoms of an overdose of Lyrasil. Since Lyrasil is for external use only, there is no risk of systemic toxicity. In case of overdose, the patient should consult a doctor for appropriate advice.
Missed dose: In case of forgetting to take 1 dose of Lyrasil 0.3%, patients should consult a doctor, do not arbitrarily double the prescribed dose.

3. Lyrasil side effects

Lyrasil is generally well tolerated. However, during the use of Lyrasil, patients may still experience some unwanted symptoms such as: Irritation, eye itching, eyelid swelling and conjunctival redness.
Patients should notify their doctor when experiencing side effects of Lyrasil for timely handling instructions.

4. Be careful when using Lyrasil

Some issues patients need to be cautious about before and while using Lyrasil are:
To prevent drug-resistant conditions, during treatment, patients should be tested for bacterial susceptibility and only use Lyrasil with the minimum dose and time required; When Lyrasil is used concomitantly with other systemic aminoglycosides, it is advisable to monitor the total serum aminoglycoside concentration; Use caution when using Lyrasil for pregnant women; Lyrasil is only used for breastfeeding women in cases of real need; The effects of Lyrasil on the ability to drive and use machines have not been studied. While driving and operating machinery, attention should be paid to the possibility that sometimes blurred vision may occur immediately after instillation of Lyrasil in the eyes. Drug Interactions: Concomitant use of Lyrasil with ototoxic and nephrotoxic agents may increase the toxicity of aminoglycosides.
During the use of Lyrasil 0.3%, patients should pay attention to listen and follow the doctor's instructions, carefully read the necessary instructions and ask immediately if they have any questions. This ensures the most effective treatment and minimizes the risk of dangerous side effects.
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