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Lomerate is a drug for the treatment of diseases related to increased gastric acid secretion. With anti-vomiting effect, reducing the feeling of bloating, indigestion after eating, the drug is being favored by many patients. So what is the right way to drink? The points that need to be paid attention to and noted when using will be shared through the article below.1. What are the uses of Lomerate?
1.1. What is Lomerate? Lomerate is a prescription drug, it belongs to the ETC group and is indicated for the treatment of esophageal ulcers caused by reflux, the prevention of gastric and duodenal ulcers caused by the use of non-steroidal anti-inflammatory drugs (NSAIDs). , or control of nausea and vomiting of CNS origin and treatment of Zollinger Ellison syndrome .
Lomerate drug has main active ingredients: Lansoprazole 30.00 mg, Domperidone maleate 10.00 mg (equivalent to 7.86 mg domperidone) and excipients: Saccrose sugar; Sodium starch glycolate; Sodium lauryl sulfate; Povidone K30; Hypromellose phthalate 50; Hypromellose 603; Mannitol; Diacetylated monoglycerides; Talc; Alcohol 96°: Purified water; Acetone.
Lomerate is prepared in the form of: Hard capsules containing enteric microcapsules and packaged in a box of 3 blisters, each blister contains 10 pills.
1.2. What does Lomerate do? Lomerate is used to treat ulcers of the esophagus caused by reflux. Long-term treatment of patients with healed esophagitis to prevent recurrence. Symptomatic treatment of gastroesophageal reflux disease. Combined with an appropriate antibacterial regimen for the definitive treatment of H. pylori and duodenal ulcer disease, reducing the risk of recurrence. Healing of gastric ulcers caused by the use of non-steroidal anti-inflammatory drugs. Prevention of gastric and duodenal ulcers associated with the use of nonsteroidal anti-inflammatory drugs in high-risk patients. Control of nausea and vomiting of central and peripheral nervous origin. Antiemetic in patients receiving cytostatic drugs or radiation therapy. Treatment of Zollinger Ellison syndrome.
2. How to use the drug Lomerate
2.1. How to take Lomerate medicine Lomerate when users take it should be swallowed whole, take the drug with filtered or boiled water and need to drink it at least 30 minutes before eating, if it is difficult to swallow, the capsule can be removed. and take the micro-granules, do not chew or crush the micro-granules. The duration of use of Lomerate should not exceed 8 weeks, because it is possible to encounter carcinoid tumors with prolonged use.
Lomerate is used for patients who are being treated under the prescription of a specialist.
2.2. Dosage of the drug Lomerate Adults and children under 12 years of age Treatment of ulcerative esophagitis caused by reflux: Take 1 tablet each time, 1 time a day for 4 weeks. If the patient is not completely cured, it can be taken for another 4 weeks. Long-term treatment for patients with healed esophagitis to prevent recurrence: Take 1 capsule, 1 time per day. Treatment of symptoms of gastroesophageal reflux disease: Take 1 tablet per day. In combination with an appropriate antibacterial regimen for the definitive treatment of H. pylori and duodenal ulcer disease, to reduce the risk of recurrence: Lansoprazole 30 mg, Amoxicillin 1 g, or Clarithromycin 500 mg, and Tinidazol all Use twice a day, and use within 10 days. Patients who need continuous treatment with non-steroidal anti-inflammatory drugs. Healing of gastric ulcers caused by non-steroidal anti-inflammatory drugs: The usual dose is 1 tablet, once a day, for 4 to 8 weeks. Prevention of gastric ulcer and duodenal ulcer caused by the use of non-steroidal anti-inflammatory drugs in high-risk patients: Take 1 tablet once a day. Treatment of Zollinger Ellison syndrome Recommended first dose: Take 1 tablet once a day. The dose is then adjusted according to the individual patient's response. Patients with impaired kidney function. No dose adjustment is required. Due to limited experience with the use of the drug in patients with renal disease, caution should be exercised in these patients. The patient has impaired liver function. No dose adjustment is required in patients with mild to moderate hepatic impairment. In patients with severe hepatic impairment should not overdose. Indigestion, flatulence 1 tablet per day, for 1 to 2 weeks. Usually medications can be taken 1 to 2 hours later than prescribed in the prescription. Unless it is a drug with strict regulations on the time of use, the patient can take the medicine a few hours after the missed dose is discovered. But if it is too close to the time to take the next dose, the patient should not take it, which can be dangerous for the body. It is necessary to strictly adhere to or consult a doctor before making a decision. In addition, anticholinergics, antiparkinsonian drugs, and antihistamines with antihistaminic properties may be helpful to control extrapyramidal reactions. There is no specific antidote for domperidone, but in the event of an overdose, it may be beneficial to detox with gastric lavage and oral administration of activated charcoal.
Lansoprazole is not removed from the circulation by hemodialysis. In one case of overdose, the patient took 600 mg of lansoprazole without any reaction.
3. Contraindications of Lomerate
In patients who are sensitive to any of the components of the drug or Benzimidazole derivatives and to Domperidone. Anticholinergics may inhibit the effects of domperidone. If these drugs must be used in combination, the patient can take Atropin after taking Domperidone. If domperidone is used with antacids or acid-suppressing drugs, domperidone should be taken before meals and antacids or acid-suppressing drugs should be taken after meals. Lomerate is not teratogenic. But for the safety of pregnant people should avoid taking the drug. Lomerate is excreted in breast milk in low concentrations; Do not use the drug while breastfeeding.
4. Notes when using the drug Lomerate
When gastric ulcer is suspected or present, the possibility of malignancy should be excluded, since treatment with Lansoprazole may relieve symptoms and delay diagnosis. Safety and effectiveness in children under 12 years of age have not been established. Pregnancy: There are insufficient clinical data on the use of lansoprazole in pregnant women. Caution should be exercised when prescribing to pregnant women. Lactation: It is not known whether lansoprazole is excreted in human milk. No studies in nursing women have been performed. Therefore, lansoprazole should not be used while breastfeeding. Patients experiencing dizziness or other central nervous system disturbances, including vision, should not drive or operate machinery.
5. Side effects of Lomerate
Digestive: Nausea, vomiting, diarrhea, constipation, abdominal pain, dry mouth, pharyngitis, taste abnormalities. Nervous system: Headache, dizziness, drowsiness, sleeping eyes, tremor. Skin: rash, urticaria, itching, hair loss in some cases. Hepatic reactions: Possible increase in liver enzymes Hematology: Thrombocytopenia, anemia, leukopenia, neutropenia, eosinophilia (rare). Other reactions: Fatigue, fever, joint pain, gynecomastia in men, lactation (rare), blurred vision in some cases. Prior to administration, the possibility of gastric ulcer malignancy or esophageal malignancy should be excluded, as this drug may improve symptoms of ulcerative malignancy and thus may delay the diagnosis of gastric cancer. letters.
6. How to store Lomerate
Store Lomerate in a cool, dry place, at a temperature not exceeding 30°C, in the original packaging and protected from light. Keep Lomerate out of the reach of children. Store the medicine for 36 months from the date of manufacture, for the medicine that has been exposed to the air, it should be used immediately. Users need to carefully read the instructions for use of Lomerate before using. Before using, check the expiration date on the medicine's packaging. If the drug is expired or the patient no longer uses it, it should be disposed of according to the recommended regulations.
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