Uses of Lincomycin 500mg

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1. Mechanism of action of Lincomycin 500mg

What are the uses of Lincomycin 500mg? Lincomycin 500mg medicine contains the main ingredient is Lincomycin belonging to the group of lincosamide antibiotics obtained from the culture of streptomyces lincolnensis or by other methods.
What is Lincomycin 500mg and how does it work? Lincomycin 500mg is a drug to treat bacterial infections and has the mechanism of action of this compound in the drug Lincomycin 500mg: Lincomycin is similar to other lincosamides attached to the 50S subunit of bacterial ribosomes like macrolides such as erythromycin, and at the same time interferes with erythromycin. early stages of protein synthesis. The main effect of the compound Lincomycin is bacteriostatic, but at high concentrations, it can kill bacteria slowly against susceptible strains.
The spectrum of effects of Lincomycin 500mg against gram-positive aerobic bacteria including staphylococcus... However, Lincomycin 500mg has no effect on enterococcus or aerobic bacteria.
Lincomycin has a fairly broad spectrum of activity against anaerobic bacteria. At high doses, the compound Lincomycin is active against gram-negative anaerobes. Lincomycin 500mg can also have some effect on protozoa, so it is used in the treatment of pneumonia. The minimum inhibitory concentrations of vancomycin against the most susceptible strains ranged from 0.05 to 2 mcg/ml/.

2. Indications and contraindications for the use of Lincomycin 500mg

What disease does Lincomycin 500mg treat? Lincomycin 500mg medicine is indicated in the treatment of otitis, bronchitis, pneumonia, dental inflammation, dermatitis, gynecological infections, osteoarthritis, treatment after surgery flare, sepsis .
However, Lincomycin 500mg is also contraindicated for some subjects with hypersensitivity to the drug's ingredients, or cases of meningitis caused by the drug entering the cerebrospinal fluid, or pregnant women.

3. Dosage and how to use Lincomycin 500mg

Lincomycin 500mg is used orally and is taken away from meals at least 1 hour before or after meals
The dose of Lincomycin 500mg applied to adults is 500mg corresponding to one tablet for once and a day of use 3 to 4 times. For children and children from 1 month old, the dose of Lincomycin 500mg from 30 to 60mg/kg/day can be applied and divided into several times a day for oral administration. In cases of severe renal failure, the dose of Lincomycin 500mg applied may be only 25 to 30% of the normal dose. It should be noted: The above recommended therapeutic dose for Lincomycin 500mg is for reference only. Therefore, before using Lincomycin 500mg, patients need to be prescribed by a doctor.
If the patient has missed a dose of Lincomycin 500mg, use the missed dose as soon as you remember it. However, if the interval between the missed dose of Lincomycin 500mg and the next dose is too close, skip the missed dose. Patients should not double the dose of Lincomycin 500mg, because it can cause drug overdose. To overcome the situation of missing doses of Lincomycin 500mg, patients can set an alarm or ask family members to remind them.
In case the patient accidentally uses Lincomycin 500mg drug more than prescribed and shows some unwanted signs such as abdominal pain, nausea and vomiting, diarrhea, fatigue, dizziness, dizziness, low blood pressure, difficulty breathing, drowsiness, itching....then need to take the patient to see a doctor right away

4. Unwanted side effects and some notes when using Lincomycin 500mg

Felodil 5mg may cause some unwanted side effects during treatment. However, with each case, Lincomycin 500mg can occur in varying degrees from mild to severe.
Some common side effects caused by Lincomycin 500mg include: flushing, dizziness, fatigue... These side effects can occur at the beginning of treatment or after increasing the dose of the drug used. use. Usually these reactions can be transient or subside over time.
However, in some cases, Lincomycin 500mg can cause serious unwanted side effects with rare reactions. These reactions may appear within minutes of using Felodil 5mg or may be longer within a few days. When serious side effects appear, such as: anaphylaxis, neutropenia, pseudomembranous colitis, esophagitis treated with oral therapy, increased liver enzymes, hypersensitivity reactions such as edema, lymphedema serum, kidney dysfunction, uremia, oliguria, cardiac arrest... the patient should stop using Lincomycin 500mg and need immediate medical assistance.
Although this is not a complete list of unwanted side effects of Lincomycin 500mg, if the patient feels unusual signs during treatment, they should immediately notify the doctor or medical staff. .
Some notes when using Lincomycin 500mg:
Lincomycin 500mg can be used with caution in cases of diseases related to the digestive tract, especially those with a history of colitis. Or the elderly and women may have severe diarrhea, with pseudomembranous colon. For allergic cases, using Lincomycin 500mg can make the allergic condition of the disease worse. People with liver failure or severe kidney failure using Lincomycin 500mg drug need to be adjusted dosage accordingly. For cases of long-term treatment with Lincomycin 500mg or children, it is necessary to periodically monitor liver function as well as hematology. Lincomycin 500mg has a neuromuscular blocking effect, so caution should be exercised when using drugs that cause unwanted side effects. Although Lincomycin 500mg has been studied in animals, there are no data on birth defects. Lincomycin 500mg can cross the placenta and reach approximately 25% of maternal serum concentrations in the umbilical cord. In addition, there are no studies that adequately control the use of Lincomycin 500mg for pregnant women. Therefore, in these cases, caution should be exercised when using Lincomycin 500mg. Lincomycin 500mg may be secreted in milk and there is also a potential risk of side effects in nursing infants taking this medicine. The drug is unlikely to affect the pharmacokinetics of gentamicin, but the safety of combining the two drugs has not been elucidated. Lincomycin 500mg can interact with Kaolin drugs that have anti-diarrheal effects and reduce the absorption of Lincomycin content. Lincomycin 500mg does not interact with theophylline Oral contraceptives may be inhibited or reduced by disturbances of normal bacteria in the intestine, blocking the enterohepatic cycle. As for neuromuscular blocking drugs, patients must be cautious when combining with Lincomycin 500mg or similar ingredients. With erythromycin due to the antagonistic nature of erythromycin and lincomycin, caution should be exercised when these drugs are used in combination. Lincomycin 500mg is made in the form of hard capsules and is indicated in the treatment of serious infections caused by sensitive bacteria such as ENT, bronchopulmonary, dental, .. To ensure effective use and avoid Unwanted side effects, patients need to use the drug strictly according to the instructions of the doctor, professional pharmacist.
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