This is an automatically translated article.
Limatex belongs to the group of anti-parasitic, anti-infective, anti-viral, anti-fungal drugs, which are prepared in the form of film-coated tablets. The main ingredient of the drug is Lamivudine, which is indicated in the treatment of chronic hepatitis B. However, during treatment with Limatex, there may be some side effects such as headache, fatigue, ... So before using Limatex, patients need to learn carefully about drug information.
1. What is Limatex?
The Limatex component is metabolized by both infected and uninfected cells to a TP derivative, the active form of the parent substance. The intracellular half-life of triphosphates in hepatocytes was 17 to 19 hours in the in vitro assay. Lamivudin-TP binding acts as a substrate for the HBV polymerase. Once the viral DNA is formed, it is blocked by the incorporation of Lamivudin-TP into the strand and terminating the strand. This binding mainly inhibits mammalian alpha and beta DNA polymerases.
2. Indications and contraindications to the use of Limatex
Limatex belongs to the group of anti-parasitic and anti-infective drugs indicated in the treatment of chronic hepatitis B in patients with evidence of hepatitis B virus replication. The drug is also combined with Zidovudine in the treatment of HIV both in HIV and AIDS. adults and children. However, Limatex is contraindicated in cases where the patient is hypersensitive to the ingredients of the drug.
3. Dosage and how to use Limatex
Limatex drug is used orally with a therapeutic dose for hepatitis B virus infection in adults is 100mg / day, and for children over 12 years old use a dose of 3mg / day. Although the maximum dose used of Limatex is 100mg/day, it is necessary to reduce the dose during the treatment of patients with renal impairment.
In the treatment of HIV in combination with Zidovudine: In adults, use Limatex at a dose of 150mg/day and twice a day in combination with Zidovudine 600mg divided into 2-3 times. In children, use Limatex at a dose of 4mg/kg/time divided into 2 times. Use up to 300mg / day and can be combined with Zidovudin 360 - 720mg / day divided into several times. In patients with renal failure with creatinine clearance less than 30ml/min, the dosage should be adjusted according to the doctor's prescription.
Note: The recommended dose of Limatex above is for reference only. Therefore, before using Limatex, patients need to follow the doctor's prescription.
4. Management of missed dose and overdose of Limatex
If you miss a dose of Limatex, use it as soon as you remember. However, if the interval between the missed dose of Limatex and the next dose is too close, skip the missed dose. Patients should not double the dose of Limatex, as this can cause an overdose. To overcome the situation of missing a dose of Limatex, patients can set an alarm or ask a loved one to remind them.
In case of accidentally using Hapacol over the prescribed dose and showing some unwanted signs, the patient should call the doctor and ask a loved one to take him to the emergency room right away.
5. Side effects when using Limatex
Limatex may cause some unwanted side effects during treatment. However, with each case, Limatex side effects can occur in varying degrees from mild to severe.
Some common side effects caused by Limatex include: Nausea and vomiting, skin rash, digestive disorders, insomnia, cough, runny nose,... These side effects may occur at the start. at the beginning of treatment or after increasing the dose of Limatex. Usually, side effects from Limatex can be transient or subside over time.
However, in some cases Limatex can cause serious unwanted side effects with rare reactions. These reactions may appear after just a few minutes of using Limatex or longer within a few days. When serious side effects appear such as: Allergic reactions, rash, recurrent pancreatitis, cramps, peripheral neuropathic pain, etc., patients should stop using Limatex and seek medical advice. get medical help immediately.
Some notes during the use of Limatex:
For pregnant and lactating women, caution should be exercised when using Limatex. Patients should be advised to use Limatex from their doctor, and carefully analyze the benefits and risks before using. Limatex may change how it works as well as increase its side effects. Therefore, to avoid Limatex drug interactions, patients should provide their doctor with a list of previously used drugs, including prescription and non-prescription drugs, herbs,... When using Limatex, people Patients should pay attention to allergic manifestations of the drug. Notify the doctor when there are abnormal signs so that the side effects of the drug can be treated promptly. Limatex should be used with caution in patients with severe renal impairment. Lamivudin 150mg should not be used alone. When patients have signs of pancreatitis, it is necessary to stop using Limatex and periodically monitor clinical and laboratory tests, especially liver function tests. Above is important information about Limatex, patients should carefully read the instructions for use and use according to the dose prescribed by the doctor to achieve the best effect. Medicines are prescribed by the doctor's prescription, patients should not self-medicate at home because they may experience side effects that are dangerous to health.
