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Liapom is indicated to help reduce the risk of stroke, heart attack, or other metabolic heart disease complications. Belonging to the group of prescription drugs, to ensure the effective use of Liapom, patients need to follow the instructions of a specialist, and refer to the information in the article below.1. What are the uses of Liapom?
1.1. What is Liapom? Liapom drug belongs to the group of cardiovascular drugs, with registration number VN-16679-13, manufactured, imported and distributed by M/s Bio Labs (Pvt) Ltd - Pakistan in Vietnam by DOHA Pharmaceutical Co., Ltd. . With the main active ingredient is Atorvastatin (as Atorvastatin calcium) 10mg.
Liapom drug is prepared in the form of film-coated tablets, blisters of 10 tablets, boxes of 3 blisters.
Liapom is recommended for use by adults and children 10 years of age and older.
1.2. What does Liapom do? Liapom is used to lower the level of "bad" cholesterol in the blood (low-density lipoprotein or LDL), increase the level of "good" cholesterol (high-density lipoprotein or HD), lower triglycerides, and treat the symptoms of diabetes. high cholesterol (hyperlipidemia). Lipid-modifying Atorvastatin should only be part of a multifactorial intervention in individuals at risk for atherosclerotic vascular disease with significant hypercholesterolemia.
Liapom is prescribed for use in the following cases:
Lowering total cholesterol, LDL-cholesterol, triglycerides and apolipoprotein B; increased HDL-cholesterol in patients with primary hypercholesterolemia. Patients with dysbetalipoproteinemia do not respond adequately to diets restricted in saturated fat and cholesterol. In adult patients with no clinically apparent cardiovascular disease, but with multiple risk factors for coronary artery disease such as retinopathy, albuminuria, smoking, or hypertension, Adults with clinically manifest coronary heart disease: Liapom reduces the risk of non-fatal myocardial infarction, reduces the risk of fatal and non-fatal strokes, reduces the risk of hospitalization for CHF, reduces the risk of chest pain. Contraindications:
Patients who are allergic to the main active ingredient Atorvastatin, HMG-CoA reductase inhibitors or any of the excipients. Patients with progressive liver disease or persistent elevations of serum transaminases with no known cause. Pregnant and lactating women. Children under 10 years old.
2. How to use Liapom
2.1. How to take Liapom Drug Liapom is taken orally, can be taken at any time of the day, regardless of meals. Swallow the tablet whole with water, do not crush or break it, and mix it with any solution or mixture for oral administration. Follow exactly as directed by your doctor or the manufacturer's recommendations. 2.2. Dosage of Liapom Adult:
Treatment of hypercholesterolemia (with or without familial) and mixed dyslipidemia: The recommended starting dose is 10 or 20 mg once daily. Patients who need a significant reduction in LDL cholesterol (approximately above 45%) can start with a dose of 40 mg once daily. The therapeutic dose range of Liapom is 10 - 80 mg orally once a day. Blood lipids should be assessed within 2 to 4 weeks after initiation of therapy or increasing the dose of Liapom so that the dose can be adjusted accordingly. Treatment of homozygous familial hypercholesterolemia: 10-80mg daily. Liapom should be combined with other lipid-lowering measures. Combination therapy: Liapom can be used in combination with Resin to increase the effectiveness of treatment. Dosage of Liapom in patients with renal impairment: No dose adjustment is required. Children:
Treatment of heterozygous familial hypercholesterolemia in pediatric patients (aged 10 to 17 years): The recommended starting dose of Liapom is 10mg/day; The usual dose range is 10 - 20mg orally 1 time per day. In cases of good response, the dose can be increased to 80 mg. Dosage for children should be individualized to achieve a therapeutic effect. Handling missed dose:
Because the drug is only used once a day, choose a fixed time to take it to limit missed doses. If you miss a dose, take it as soon as you remember, and take it at the same time the next day. Treatment of Overdose:
There is no specific treatment regimen for Atorvastatin overdose, the direction of treatment is mainly based on the patient's condition. Blood biochemical tests to check liver function and serum CK levels should be performed.
3. Note when using Liapom
Before starting treatment with Liapom, it is necessary to pay attention to exclude the causes of secondary dyslipidemia and periodically check the lipid index, it is recommended to conduct the test less than 4 weeks. Use Liapom with caution in patients with liver dysfunction, patients with heavy alcohol consumption. During treatment with Liapom, patients still need to have a reasonable diet like before treatment with the drug. If you are taking Liapom and find out you are pregnant, stop taking it immediately. Liapom should be used with caution in patients with prior hemorrhagic stroke or lacrimal infarction, due to the potential risk of hemorrhagic stroke. In rare cases, the active ingredient Atorvastatin can affect skeletal muscle causing myalgia, myositis and possibly progression to rhabdomyolysis - a potentially life-threatening condition characterized by high concentrations Significantly elevated creatine kinase (CK) (10 times ULN), myoglobinuria and myoglobinaemia can lead to renal failure.
4. Side effects of Liapom
Atorvastatin was generally well tolerated, side effects were usually mild and transient.
The most common side effects of Liapom include:
Joint pain; Stuffy nose; Sore throat; Nausea or vomiting, diarrhea. Liapom can cause serious side effects such as:
Pain or burning when you urinate; Upper abdominal pain; Feeling tired, weak; Loss of appetite; Dark urine, little or no urinating; Yellowing of the skin or eyes; Swelling in your feet or ankles; Short of breath .
5. Liapom drug interactions
Anticoagulants, Indandione in combination with Liapom will increase bleeding time or prothrombin time. Prothrombin time should be closely monitored in patients receiving concomitant anticoagulants. Digoxin: Co-administration with Liapom causes a slight increase in serum digoxin concentrations. Concomitant use of Liapom and oral contraceptives increases plasma concentrations of Norethindrone and Ethinyl estradiol. Atorvastatin plasma concentrations are significantly increased when Liapom is co-administered with Azole antifungals or selective Macrolide antibiotics. Consider whether the benefit of administering a lipid-modified dose of Niacin concurrently with Liapom outweighs the increased risk of myopathy and rhabdomyolysis. If concurrent use is still decided, signs and symptoms of myopathy should be observed, especially during initiation of Liapom therapy and during titration of more or more doses of either drug. Note the same with Cyclosporine, Gemfibrozil, Erythromycin, immunosuppressive drugs.
6. How to store Liapom
The shelf life of Liapom is 24 months from the date of manufacture. The medicine should be stored in a cool, dry place, away from direct sunlight, or places that are too humid, such as bathrooms, refrigerators. Reasonable storage temperature is below 30 degrees Celsius. Keep out of reach of children. Above is all information about Liapom drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Liapom is a prescription drug, you need to use it as prescribed by your doctor, absolutely do not self-treat at home.
