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Levocetirizine DIHCI-Teva 5mg is a second generation antihistamine used in the treatment of hay fever-induced allergic rhinitis and long-term rash of unknown cause.1. What is Levocetirizine dihcl?
Levocetirizine DIHCI- Teva 5mg has the ingredient Levocetirizine (as Levocetirizine dihydrochloride) 5mg, used in the treatment of diseases such as:Treatment of symptoms of non-seasonal allergic rhinitis, seasonal allergic rhinitis and chronic idiopathic urticaria. Treat allergy symptoms such as watery eyes, runny nose, sneezing, hives and itching.
2. Dosage and usage
How to use: The drug is prepared in the form of film-coated tablets, so the drug should be taken orally, the patient can take it during or after a meal. Duration of use: Long or short duration of medication will depend on the progression of the disease. With hay fever and cases of patients exposed to pollen, the drug is usually used for a short time of less than a week, for a long time, from 3 to 6 weeks. However, there have also been recorded patients taking levocetirizine dihcl for up to 6 months. Dosage: Dosage for adults and children over 12 years: Use the recommended dosage of 5 mg once daily. For children 6 to 12 years of age: Use the recommended daily dose of 5mg, taken once daily. Note: For children under 6 years of age, Levocetirizine is not recommended because there are not enough clinical trials to demonstrate the safety and effectiveness of the drug in these subjects. Elderly patients: Currently, there are no data to suggest that a dose reduction is necessary in elderly patients when renal function is normal. For patients with renal impairment: The amount of drug used and the interval between doses should be adjusted, depending on the creatinine clearance rate (CLcr). Specifically as follows: Creatinine clearance rate above 80 ml/min using the drug dosage is 1 tablet, once per day. Creatinine clearance rate from 50 - 79 ml/min using a dose of 1 tablet, once daily. Creatinine clearance rate from 30 to 49 ml/min using a dose of 1 tablet, once every 2 days . For patients with end-stage renal failure and on hemodialysis, the use of levocetirizine dihcl is not recommended. For patients with liver failure: No need to adjust the dose of the drug, apply the same dosage as the normal person. For patients with both liver and kidney failure: Need to adjust the dose of the drug, the patient can refer to the dosage for patients with renal failure above. Contraindications: Patients with hypersensitivity to levocetirizine, piperazine derivatives or any of the ingredients. Do not administer to patients with severe renal impairment with creatinine clearance less than 10 ml/min.3. Overdose and how to handle it
When using overdose will experience symptoms such as drowsiness, this expression is common in adults, with children will have more diverse manifestations such as agitation and restlessness, drowsiness.Treatment of overdose : Currently, there is no specific antidote for levocetirizine overdose. If the drug overdose is allowed, the patient should be treated with symptomatic and supportive treatment. In case of severe reactions, the doctor will prescribe gastric lavage if the patient has only taken the drug for a short time. Dialysis to remove Levocetirizine from the body is not an effective way.
4. Be careful when taking medicine
Patients should be careful not to exceed the recommended dose. Doctors do not recommend using levocetirizine dihydrochloride in children under 6 years of age. During the use of the drug should not drink alcohol because it can affect the effectiveness of the drug or cause unwanted reactions. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take levocetirizine dihcl. Pregnancy: Data from several clinical trials have shown that the use of the drug by pregnant women will not affect the health of the mother or the fetus. However, these data are incomplete, so caution should be exercised when levocetirizine is administered to pregnant women. For lactating women: Levocetirizine is likely to be excreted in breast milk. Therefore, the use of Levocetirizine Teva is not recommended during lactation. Effects on ability to drive and use machines: Levocetirizine has no or negligible influence on the ability to drive and use machines. However, some patients may experience drowsiness, fatigue and weakness after taking the drug. Therefore, patients intend to drive, participate in activities that may be dangerous, so patients should carefully consider whether to take the drug or not.5. Side effects
Affects liver function test results, although this is very rare, patients should also note:Cardiovascular: Causes arrhythmia reactions with palpitations, this is also a Very rare reaction. Causes nervous system disorders with somnolence, headache. Causes eye disturbances with visual disturbances. Causes respiratory, thoracic and mediastinal disorders with symptoms such as dyspnea. Gastrointestinal disturbances with dry mouth, abdominal pain and nausea. Causes skin and soft tissue disorders with angioedema, pruritus, rash and urticaria Systemic disturbances and reactions at the site of application such as fatigue and asthenia. Immune system disturbances with anaphylaxis and hypersensitivity reactions. Hepatobiliary disorders with manifestations of hepatitis.
6. Interactions with other drugs
There are also not many drug interaction studies of levocetirizine with other drugs, including the interaction between levocetirizine and inducers of CYP3A4. The extent of absorption of levocetirizine is not decreased when taken with meals, although the rate of absorption is slowed. In susceptible patients, concomitant use of cetirizine or levocetirizine with alcohol or other CNS depressants may affect the central nervous system.Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.