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Laferine has the main ingredient of dried ginkgo biloba leaves, which is used in the treatment of peripheral arterial circulatory disorders, improving cerebral blood circulation. The following article provides you with information about the uses and precautions when using Laferine.
1. What does Laferine do?
What does Laferine do? Laferine is prepared in the form of an oral solution, each 20ml tube contains 80mg of dried Ginkgo leaf extract. Other excipients include: D - Sorbitol solution 70%, corn syrup, poloxamer, sodium benzoate, enzymatically modified stevia, pineapple flavor, anhydrous citric acid, purified water.
Mechanism of action: PAF antagonist: Ginkgo biloba leaves have a strong inhibitory effect on PAF, a substance that promotes platelet aggregation. Therefore, the drug improves cerebral and peripheral blood circulation thanks to its antithrombotic effect, improves blood circulation, prevents angioedema.
Effect of scavenging free radicals: Ginkgo leaf extract has a strong effect on scavenging free radicals, through which the drug improves cell wall damage and impaired blood circulation syndrome, especially damage to nerve cells and blood vessels.
Impact on energy metabolism: Ginkgo leaf extract has the effect of increasing glucose utilization in ischemic conditions, and Laferine helps to avoid damage to brain cells caused by disorders of energy metabolism. .
2. Indications and contraindications of the drug Laferine
2.1.Indications Indications for the use of Laferine in the following cases:
Dementia such as memory loss, depression and headaches, decreased concentration. Especially in the elderly, tinnitus, hearing loss, dizziness. Cerebral circulatory insufficiency Treatment of circulatory disorders of peripheral arteries, with symptoms of claudication. Support treatment of sequelae of traumatic brain injury, cerebrovascular accident. Some cases of retinal ischemia. Negative positive. 2.2.Contraindications Laferine is contraindicated for use in the following cases:
Patients with hypersensitivity to any ingredient of Laferine. Acute phase of cerebrovascular accident, acute myocardial infarction, low blood pressure. Intellectual disability, mental retardation, behavioral disorders in children. Pregnant women. Patients with coagulopathy or bleeding. Children under 12 years old.
3. How to take Laferine?
3.1.Using method and dosage Laferine is used orally, not by infusion. The patient can dilute the drug solution with half a glass of water to drink.
Dosage of Laferine is as follows:
Treatment of peripheral arterial circulation disorders, tinnitus, dizziness: Dosage: 20mg/time (1 tube) x 2-3 times/day. Improve cerebral blood circulation (decreased concentration, memory loss, depression, dementia): 20mg - 40mg/time (1-2 tubes) x 3 times/day; or use a dose of 40mg / time (2 ampoules) x 2 times / day. It should be noted: Laferine dosage can be adjusted according to the age and symptoms of each patient.
Laferine overdose and management: Currently, there are no reports of Laferine overdose. In case of overdose of Laferine, the patient should immediately go to the nearest medical facility for timely treatment.
Missing a dose of Laferine and what to do: If you forget to take a dose of Laferine, take it as soon as possible. If it is almost time for the next dose of Laferine, skip the missed dose and take the next dose as scheduled. In addition, care should be taken not to double the dose of Laferine for treatment.
4. Undesirable effects when using Laferine drug
Some undesirable effects when using Laferine have been reported such as digestive disorders, headache or skin rash; however these side effects are usually mild and rarely occur. In some cases, bleeding time may be prolonged.
In case of using the drug, the patient experiences serious side effects, it is necessary to stop using Laferine and go to the nearest medical facility for timely treatment.
5. Notes when taking Laferine
In the course of using Laferine, patients should note some of the following issues:
Should stop using Laferine before 36 hours before surgery. Laferine should not be used in patients with coagulopathy. Caution should be exercised in concomitant use of Laferine with anticoagulants such as Heparin, Warfarin, Coumarin. Patients with a hypersensitivity reaction to Ginkgo leaf extract should not take this medicine. Laferine contains sodium benzoate, which can irritate the skin, eyes and mucous membranes. Pregnant women and children under 12 years of age: Laferine should not be used. Breast-feeding: There is no complete information on the safety and efficacy of Ginkgo leaf extract in nursing women. Be careful and read the instructions carefully before using Laferine for this subject.
6. Drug interactions
Increased risk of bleeding when Laferine is used concomitantly with anticoagulants, antithrombotic drugs such as warfarin, aspirin, heparin... Antiepileptic drugs carbamazepine, valproic acid: When used concomitantly with high doses of Laferine, reduce the effectiveness of these drugs. Ginkgo may increase the effectiveness of treatment as well as the side effects of MAOIs (Phenelzine, Isocarboxazid, Tranylcypromine), and selective serotoin inhibitor antidepressants (Sertralin). Laferine medicine has the main ingredient is dried ginkgo leaf extract, which is used in the treatment of peripheral arterial circulatory disorders, improving cerebral blood circulation. The drug is contraindicated to use Laferine for pregnant and lactating women, children under 12 years of age. Dosage is adjusted according to the condition and clinical response of the individual patient. Before taking Laferine, it is best to consult with your doctor for instructions on safe and effective use of the drug.
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