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Knotaz contains the main ingredient is Pantoprazole, which is used in the treatment of some gastrointestinal diseases. So what is Knotaz and how should it be used properly?
1. What is Knotaz?
Knotaz medicine contains the active ingredient Pantoprazole Sodium with a concentration of 40mg in the form of enteric coated tablets. It is a selective proton pump inhibitor and a derivative of Benzimidazole. The drug is rapidly absorbed from the gastrointestinal tract but may vary depending on dose and gastric pH. When used orally, the drug can be absorbed up to 70% with repeated administration.
2. Effects of Knotaz
Knotaz drug has the ability to specifically and irreversibly inhibit the proton pump thanks to its highly selective mechanism of action on the gastric cell wall, so it works faster and more effectively than other drugs. Ulcer healing can reach 95% after 8 weeks of treatment.
An advantage of Knotaz is that it has little effect on pepsin secretion, gastric juice volume as well as intragastric factors and gastric contractility.
3. Indications for use of the drug Knotaz
Knotaz drug is indicated in the treatment of a number of conditions such as:
Patients with gastric ulcer or duodenal ulcer. Gastroesophageal reflux disease or acid reflux disease. Use in combination with antibiotics to eliminate Helicobacter pylori infection.
4. How to use Knotaz
The drug is used by taking whole tablets with the following dosage:
Treatment of peptic ulcers with a dose of 40mg/day, lasting 4-8 weeks. Treatment of gastroesophageal reflux with a dose of 40mg / day, lasting 8 weeks. After this time, if the ulcers do not heal, consult a doctor for another 8 weeks.
5. Contraindications to the use of Knotaz
Do not use Knotaz for patients with a history of sensitivity to Pantoprazole. Currently, research documents on the effectiveness of Pantoprazole when used during pregnancy are limited. Therefore, do not use the drug for pregnant and lactating women to limit possible risks.
6. Side effects when using Knotaz
During the use of Knotaz medicine may occasionally occur headache or mild diarrhea. Some rare cases such as: Nausea, flatulence, upper abdominal pain, skin rash, itching and dizziness.
There are some more isolated cases where a reaction of fever, edema, thrombophlebitis may occur.
Above is all information about the uses, indications, usage, dosage and notes and precautions when using Knotaz. This is a prescription drug, so the patient should not arbitrarily use it under any circumstances.
