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Intaxel is available in the form of a solution for intravenous infusion, the main ingredient is Paclitaxel 30mg/5ml. The drug is used in the treatment of advanced epithelial ovarian cancer or lung cancer, breast cancer. Complying with indications, the dose of Intaxel 30mg will help patients improve treatment effectiveness and avoid unwanted side effects.
1. Uses - Indications for Intaxel
Intaxel is often combined with the drug Doxorubicin in the treatment of cancer diseases such as:
Metastatic or recurrent breast cancer. Small cell lung cancer. Kaposi cancer associated with AIDS. Metastatic ovarian cancer.
2. Contraindications of Intaxel 30mg/5ml
Intaxel is contraindicated for:
People who are sensitive to the ingredients and excipients in Intaxel. People with neutrophils < 1500/mm3 (1.5 x 109/liter). Have motor neuron diseases. Women who are pregnant and breastfeeding. Children under 18 years old.
3. Dosage and how to take Intaxel
How to use: Intaxel is used by intravenous infusion. Note that when preparing Intaxel, it is necessary to ensure sterility.
Dosage: Intaxel infusion at a dose of 175mg/m2 over 3 hours. Can be used again after 3 weeks.
Note:
Intaxel dose is only used when the neutrophil count is > 1.5 x 109/liter (1,500/mm3) and platelets > 100 x 109/liter (100,000/mm3). In the case of patients with leukopenia <0.5 x 109/liter (500/mm3), the dose should be reduced by 20%. The dose of Intaxel should be reduced in patients with impaired or impaired liver function. In case transaminase increases 10 times higher than normal or bilirubin is greater than 7.5 mg / 100 ml (equivalent to 5 times higher than normal), do not use Intaxel.
4. Intaxel drug interactions
Intaxel may interact with:
Cisplatin drug; Ketoconazole drug. To avoid interactions, before being prescribed Intaxel, patients should inform their doctors about all the drugs they are using, including dietary supplements. The doctor will base on that to prescribe the appropriate Intaxel.
5. Side effects of Intaxel 30mg
At therapeutic doses, Intaxel is well tolerated. However, in the process of using Intaxel, patients may still experience side effects such as:
Bone marrow failure; Lower blood pressure; Increase liver enzymes ; Musculoskeletal pain; Digestive disorders; Hair loss; Peripheral neuropathy ; Anorexia; Nausea and vomiting; Diarrhea. If you experience these symptoms, the patient should stop using Intaxel and notify the doctor for appropriate treatment.
6. Notes and cautions when using Intaxel
Use caution when using Intaxel in patients with heart disease. Hypersensitivity prophylaxis should be used prior to treatment with Intaxel. People with a history of peripheral neuropathy, the elderly, and people who drive or operate machinery should use caution when taking Intaxel. Above is all information about Intaxel, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Intaxel at home because there may be unwanted side effects.
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