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Ibandromex is a drug that helps reduce bone resorption, reducing the risk of fractures. It is used in a controlled manner to reduce the risk of osteoporosis and fractures in people at high risk.
1. What is Ibandromex?
Ibandromex medicine has the main ingredient is Ibandronic Acid (in the form of Sodium Ibandronate monohydrate 168.75mg) 150mg, prepared in the form of film-coated tablets.
Ibandronate is a nitrogenous aminobisphosphonate, which has potent, selective action on bone tissue and specifically inhibits osteoclast activity without directly affecting bone formation. The selective action of ibandronate on bone tissue is based on the compound's high affinity for hydroxyapatite, the basic bone mineral.
When taken with the drug Ibandronate may lead to actual bone mass enhancement and reduction in fracture rates through decreased bone turnover in postmenopausal women.
2. Uses of the drug Ibandromex
The drug is effective in the prevention and treatment of postmenopausal osteoporosis. Reducing the risk of pathological fractures in postmenopausal people at high fracture risk.
Contraindications: Do not use Ibandromex for the following subjects.
Hypersensitivity to the main active substance or to any other excipients. Esophageal abnormalities that delay the passage of food in the esophagus, such as esophageal stricture, achalasia. Severe kidney failure; Hypocalcemia and vitamin D deficiency. Unable to stand or sit upright for at least 60 minutes; The drug contains Lactose, so it should not be used for people with lactase deficiency, galactose intolerance, glucose-galactose malabsorption.
3. Dosage and how to use Ibandromex
How to use: The drug is taken orally, should be taken on an empty stomach. When swallowing the tablet whole with a glass of water, be careful not to take mineral water, coffee, juice, food, supplements or other medications or liquids other than water. Do not chew, crush or allow the medicine to dissolve in the mouth. Take the medicine in the morning, do not lie down after taking the medicine, but sit or stand for at least 1 hour after taking it and do not eat within that 60 minutes.
Dosage:
Adults: take 150mg, one 150mg tablet per month. Should choose the most memorable day of the month to take, limit missed doses. Patients with renal impairment: Ibandromex is not recommended for use in patients with creatinine clearance less than 30 ml/min due to limited clinical experience. No dose adjustment is required for patients with mild or moderate renal impairment when creatinine clearance is equal to or greater than 30 ml/min. Patients with hepatic impairment or the elderly (> 65 years old): No dosage adjustment necessary Children under 18 years of age: have not been studied in this population, therefore should not be used. How to handle missed dose: If you forget to take your medicine on the selected day, you should not take it after that. If you remember the missed dose, there are more than 7 days left before taking the next dose: You should take 1 pill in the morning as soon as you remember, then take 1 pill on the day you remember. marked. If remembering when the next dose is less than 7 days away: Skip the missed dose, wait until the next dose, then take 1 tablet on the date marked on the calendar. Do not take 2 pills in the same week. Overdose: When taking the drug, if you take more than 1 tablet by mistake, you should immediately drink a large glass of milk or antacids and notify the doctor immediately, do not induce vomiting or lie down because there is a risk of causing real irritation. esophagus and vomiting. Some symptoms of nausea, vomiting, abdominal pain, heartburn, esophagitis, gastritis or stomach ulcer may occur with overdose.
4. Side effects of the drug Ibandromex
Some possible side effects when taking the drug include:
Common: Hypocalcemia; Esophagitis, abdominal pain, indigestion, nausea; Uncommon: Anemia; Psychosis, neurological dysfunction; taste disturbances; Blood in urine, duodenal ulcer, gastritis, dysphagia, dry mouth; Itchy; Rare: Eye inflammation; Atypical and parafemoral fractures of the femur; Asthma exacerbations; In which, the most serious are femur fractures and hypersensitivity reactions. Need to go to a medical facility immediately for timely treatment. Also, tell your doctor if you experience any side effects.
5. Things to note when taking Ibandromex
Be aware of the risk of hypocalcaemia: Ibandronic acid, like other bisphosphonates, may cause a temporary decrease in serum calcium values. Treat hypocalcaemia, bone and mineral metabolism disorders, if present, before starting ibandronic acid. All patients need to be supplemented with calcium and vitamin D when taking it.
Should check dental problems before taking the drug, minimize dental procedures during the drug use. Take care of your teeth during and after taking the medicine.
Osteonecrosis of the jaw has been reported in very small numbers in premenopausal patients.
Pregnant and lactating women: The drug should not be used by pregnant and lactating women.
Ibandromex tablets can cause serious problems in the stomach or esophagus. Stop taking the medicine and seek medical attention right away if you have chest pain, new or worsening heartburn, or pain when swallowing.
Limit smoking, alcohol or should quit smoking and drinking alcohol, because it can reduce mineral density in bones, increasing the risk of fractures.
Drug interactions: Drugs and food supplements (vitamins, minerals, Ca, Fe, Mg supplements), food, drinks, medications, aspirin, non-steroidal anti-inflammatory drugs (NSAIDs) are all dangerous. potential for drug interactions. Be careful not to use them at the same time.
Storage: Store in sealed packaging, the storage temperature is below 30 degrees Celsius. Keep the medicine out of the reach of children.
Hopefully, with the above information about the drug, you know what Ibandromex is and what to note when using it. This is a drug prescribed by a doctor and is closely monitored. If you have any problems while taking the medicine, you should inform your doctor for the best advice.
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