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Hairine 40mg for intestinal and uterine spasms, contains the active ingredient alverine citrate, a smooth muscle spasm reliever, in conditions such as irritable bowel syndrome, diverticulitis of the colon and pain primary dysmenorrhea, renal colic... Knowing the information about the drug will help the process of use be more effective.1. What is Harine?
Harine contains the active ingredient alverine citrate, a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and conditions similar to diverticulitis of the colon.... In addition, it can also be used to help relieve pain. menstrual periods .Mechanism: Reduces intestinal sensitivity, inhibits 5HT1A receptors and blocks calcium channels.
2. Dosage and how to use Harine
Currently, the dosage of Hairine 40mg is recommended to be used as follows:
Oral dose for adults 1-2 tablets x 1-3 times/day. Not for use in children under 12 years of age. How to handle missed dose and overdose:
When missed dose:
Use as soon as you remember (use as soon as possible). If it is almost time for your next dose, skip the dose and take the next dose. In case of overdose:
Symptoms: May cause hypotension, appear symptoms such as dizziness, tachycardia, dilated pupils, blurred vision, dry mouth and throat, difficulty breathing or urinating similar to poisoning Atropine. Management: Treat like atropine poisoning with supportive antihypertensive therapy.
3. Common side effects when using Harine
The following undesirable effects are encountered:
Immune system disorders: allergic reactions, anaphylaxis. Nervous system disorders: headache, dizziness. Respiratory, thoracic and mediastinal disorders: wheezing, dyspnea. Gastrointestinal disorders: nausea. Hepatobiliary disorders: jaundice due to hepatitis (usually resolves spontaneously on discontinuation of the drug), abnormal liver function tests. - Skin disorders: appearance of itching, rash.
4. Notes when using Harine 40mg?
For pregnant women: The drug is not teratogenic. Preclinical data on the safety of the drug are limited in this population. Harine 40mg is not recommended during pregnancy..
For women who are breastfeeding: not recommended.
Harine 40mg contains alverine citrate is an antispasmodic that has a direct effect on smooth muscle specifically on the smooth muscle of the gastrointestinal tract and uterus, at therapeutic doses does not affect tracheal, cardiac and vascular muscles. blood.
After oral administration, alverine is absorbed and rapidly metabolized to the primary active metabolite, which is further converted to two secondary metabolites. All metabolites have high renal clearance indicating that they are eliminated by active renal excretion. Between 1 and 1/2 hours after oral administration: the active metabolite peaks in plasma concentrations.
With alverine: plasma half-life is 0.8 hours and the major active metabolite is 5.7 hours.
The above is important information about the drug Harine 40mg, but cannot completely replace the advice of a doctor or pharmacist. Therefore, when you intend to use the drug, you should consult a qualified person to use the drug to achieve high efficiency.
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