This is an automatically translated article.
Haemostop drug is prepared in the form of an injection solution with the main ingredient being Tranexamic Acid 50mg/ml. So what is Haemostop drug, how to use it, how to use it and how to pay attention when using it?
1. What is Haemostop?
Haemostop is a drug that acts on the blood, with the main active ingredient being Tranexamic Acid, this active ingredient inhibits the fibrinolytic system, by inhibiting the activation of plasminogen into plasmin, making plasmin not be generated. out.The effects of tranexamic acid include:
Anti-plasmin effect: Tranexamic acid binds strongly to the lysine binding site (LBS), which has an affinity for fibrin of plasmin and plasminogen, and inhibits the binding of plasmin and plasminogen. binding of plasmin and plasminogen to the fibrin molecule. Therefore, degradation by plasmin will be strongly inhibited. The presence of antiplasmin agents in the blood plasma, such as a2-macroglobulin, further enhances the antifibrinolytic effect of tranexamic acid. Hemostatic effect: Excessive plasmin will cause inhibition of platelet aggregation, inhibition of the breakdown of coagulation agents... but even a slight increase in plasmin causes specific degradation of platelets. fibrin occurs earlier. Thus, in normal bleeding situations, the presence of tranexamic acid induces hemostasis by eliminating fibrinolysis. Anti-allergic and anti-inflammatory effects: Tranexamic acid inhibits the production of kinins and other active peptides... by plasmin, these substances can cause increased vascular permeability, allergic reactions. and inflammatory lesions.
2. Indications and contraindications of Haemostop
Haemostop is indicated in the following cases:
Abnormal bleeding during and after surgery. Bleeding in obstetrics and gynecology, urology. Hemorrhagic disease. It's business. Bleeding in prostate disease. Hemolysis due to pulmonary tuberculosis. Renal bleeding. Nosebleed . Haemostop drug is contraindicated in the following cases:
People with hypersensitivity to the components of Haemostop drug. Pay attention to precautions when using Haemostop drug in the following cases:
Patients with thrombosis or coagulation-destroying diseases. Elderly.
3. Dosage and how to use Haemostop
Haemostop is used intravenously or intramuscularly, by medical staff.
Dosage of Haemostop drug should be according to the doctor's prescription, the reference dose is as follows:
The usual dose is 250 - 500mg/day intravenously or intramuscularly, used 1-2 times/day. Dose 500 - 1000 mg/time IV or 500 - 2500mg/time IV as needed during and after surgery.
4. Side effects of Haemostop
During the use of Haemostop, you may encounter side effects of the drug such as:
Digestive disorders. If you see any unusual symptoms when using Haemostop, immediately notify your doctor or medical staff at the place of treatment for timely treatment.
5. Interaction of Haemostop with other drugs
Haemostop may interact when used with oral contraceptives containing estrogen.
Above is all information about Haemostop drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Haemostop is a prescription drug, you need to use it as prescribed by your doctor, absolutely do not self-treat at home.
