This is an automatically translated article.
Gumitic medicine is made in the form of soft capsules, with the main ingredient being alpha lipoic acid. It is used in the treatment of sensory disturbances caused by diabetic polyneuropathy.
1. What does Gumitic do?
What disease does Gumitic medicine treat? The main ingredient of the drug is alpha lipoic acid 200mg. Alpha lipoic acid is a coenzyme with strong antioxidant effects. After attacking the free radicals, it can return to its active form and restore other antioxidant compounds (e.g. vitamin C, vitamin E, glutathione, coenzyme Q10,...).
Besides, this ingredient also has many uses such as: Participate in the synthesis of glutathione; combined with Omega - 3 to prevent cognitive decline and brain activity related to Alzheimer's disease; stimulates the production of cAMP, inhibits the cytotoxicity of NK cells and inhibits the synthesis of Interferon gamma; enhances collagen biosynthesis in human skin structures; inhibiting the influence of Chrysene in cigarette smoke, improving function after stroke or cerebrovascular accident,...
Indications for using Gumitic:
Treatment of sensory disorders caused by diabetic polyneuropathy. Gumitic is contraindicated in people with hypersensitivity, allergies to excipients, drug components and children under 18 years of age.
2. Usage and dosage of Gumitic
The drug is taken orally. Patients should take the tablet whole with a sufficient amount of water on an empty stomach (approximately 30 minutes before eating) because food may reduce the absorption of the drug if taken concomitantly. Patients should take the drug regularly, maintain with a suitable frequency because diabetic polyneuropathy is a chronic disease that requires long-term treatment.
The recommended dosage of Gumitic is as follows:
Adults: Take a dose of 3 tablets/time/day or 1 tablet/time x 2-3 times/day; Elderly: No need to change dosage; Patients with liver failure: Take Gumitic as prescribed by your doctor. In the case of an overdose of Gumitic, the patient may experience nausea, vomiting and headache. After drinking large amounts of alpha lipoic acid (about 10-40g) with alcohol, severe toxicity or death can occur. Clinical signs of toxicity are usually psychomotor disturbances, impaired consciousness, development of generalized seizures, and lactic acidosis. In addition, patients may experience shock, hemolysis, muscle breakdown, hypoglycemia, disseminated thromboembolism, multi-organ failure and bone marrow failure,...
When using Gumitic drug overdose and suspected If severe toxicity is suspected (eg, doses above 6g in adults and over 50mg/kg body weight in children), immediately take the patient to the emergency room to manage the poisoning by inducing vomiting, gastric lavage, the use of activated charcoal,... The treatment of generalized seizures, lactic acidosis or other serious conditions should be carried out on the principles of supportive care and symptomatic treatment. The benefit of peritoneal dialysis, hemodialysis, or other alpha lipoic acid exclusion filtration methods is not conclusive.
If you forget to take Gumitic once, you should take it as soon as you remember (take it 30 minutes before or 2 hours after eating). If the above time is exceeded, do not take the supplementary dose, but continue with the dosing schedule as previously planned.
3. Side effects of the drug Gumitic
When using Gumitic, patients may experience some side effects such as:
Digestive system: Nausea, vomiting, stomach - intestinal pain, diarrhea; Immune system: Allergic reactions (rash, urticaria, itchy skin), insulin autoimmune syndrome; Nervous system: Change or disturbance of taste; Metabolism and nutrition: Hypoglycemia, dizziness, headache, sweating, vision changes,... When experiencing side effects of the drug, especially allergic reactions such as rash, difficulty breathing, swelling of the lips, tongue, throat or face, the patient should be taken to the emergency room immediately. Gumitic should be stopped and a doctor should be called at once if the patient has weakness, hunger, low blood sugar, headache, sweating, dizziness, irritability, confusion, heart palpitations, restlessness or sensation. dizzy.
4. Be careful when using Gumitic
Before and during the use of Gumitic, patients should note:
The use of Gumitic can cause insulin autoimmune syndrome in patients with genotype sensitive leukocyte antigens (mainly Japanese people). and Korea); Gumitic contains Sorbitol, so it should not be used in patients with hereditary problems of fructose intolerance; Gumitic contains soybean oil, which may cause allergic reactions (including anaphylaxis) in patients who are allergic to soybean oil. If you are allergic to beans or peanuts it is best not to take this medicine; You should consult your doctor if: You are taking Gumitic but your condition does not improve or worsens, you experience side effects of the drug, are pregnant or breast-feeding, when you want to stop taking the drug, you have liver or kidney failure. , who is suffering from another illness; Pregnant and lactating women, if using Gumitic, should use it with caution under the supervision and advice of a doctor; The side effects of Gumitic drugs such as headache, dizziness, sweating, visual disturbances may affect the ability to drive, operate machinery, so caution should be exercised when used in this group of subjects; Blood glucose should be checked and the dose of Gumitic adjusted if necessary (although hypoglycaemic side effects are rare).
5. Gumitic drug interactions
Some drug interactions of Gumitic patients should be aware of:
Diabetes drugs or insulin, if used concurrently with Gumitic drugs, have the potential to increase the hypoglycemic effect. It is advisable to monitor the patient's health when using Gumitic together with antidiabetic drugs, especially in the early stages of treatment. In special cases, the dose of insulin or antidiabetic agents can be reduced to prevent the manifestation of hypoglycemia; Alpha lipoic acid when used concurrently with Cisplatin will lose the effect of Cisplatin; Metal compounds such as iron, magnesium or calcium-containing dairy products can also interact with Gumitic (because alpha lipoic acid is a metal complex). If the patient is prescribed to use Gumitic every day about 30 minutes before breakfast, products containing iron, magnesium and calcium should be used at noon or in the afternoon; Concomitant use of alpha lipoic acid with valproic acid, sodium valproic will reduce the bioavailability of alpha lipoic acid; Regular alcohol use increases the risk of developing neurological diseases, reducing the effectiveness of treatment with alpha lipoic acid. Therefore, patients with diabetic polyneuropathy should avoid alcohol, even during drug-free periods. The use of Gumitic drug needs to be persistent for a long time, so patients need to pay attention to follow all instructions and instructions of the doctor. If experiencing side effects or have any questions, patients should contact their doctor immediately for appropriate advice.
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