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Gabanad 300 medicine has the main ingredient is Gabapentin 300 mg, belongs to the group of psychotropic drugs. Gabanad medicine 300mg is widely used in supporting the treatment of epilepsy, inflammatory diseases of peripheral nerves... Find out general information about the composition, uses, dosage and side effects of the drug. Gabanad 300 will help patients improve treatment efficiency.
1. What is Gabanad 300?
Gabanad 300 is made under hard capsules, with main ingredients including:
Active ingredient: Gabapentin 300 mg. Excipients: Just enough for 1 hard capsule of 300 mg. Gabapentin is used as the active ingredient in a number of antiepileptic drugs, but its mechanism is currently unclear. Some studies have shown that the chemical structure of the active ingredient Gabapentin is similar to the inhibitory neurotransmitter Gamma Aminobutyric Acid (GABA). However, unlike drugs that interact with Synaptic GABA receptors such as Benzodiazepines, Valproate, Barbiturates, GABA reuptake inhibitors, GABA transaminase inhibitors, GABA receptor agonists or prodrugs As a substance of GABA, Gabapentin does not act directly on GABA receptors, that is, does not alter the structure, metabolism, uptake and release of GABA.
2. What are the effects of Gabanad 300?
Gabanad 300 is indicated for treatment in the following cases:
Support treatment of partial seizures. Pain from peripheral neuritis in adults.
3. Contraindications of Gabanad 300:
Hypersensitivity to any component of the drug Gabanad 300. History of allergy to other drugs containing the active ingredient Gabapentin. Children < 3 years old.
4. Dosage and usage of Gabanad 300:
4.1. Partial epilepsy: Adults or children ≥ 12 years old
Day 1: Take 1 tablet (300 mg) / time x 1 time / day. Day 2: Take 1 tablet (300 mg)/time x 2 times/day. Day 3: Take 1 tablet (300 mg)/time x 3 times/day. Then: Slowly increase by 300 mg per day until effective. The effective dose is usually 1-2 tablets (300-600 mg)/time x 3 times/day. The maximum daily dose should not exceed 8 tablets (2400 mg). Children 6-12 years old
Starting dose Day 1: Take 10 mg/kg/day divided into 3 times/day. Day 2: 20 mg/kg/day divided into 3 times/day. Day 3: Take 25-35 mg/kg/day divided into 3 times/day. Maintenance dose Children 26 - 36 kg: Take 1 tablet (300 mg)/time x 3 times/day. Children 37 - 50 kg: Take 1 tablet (300 mg)/time x 4 times/day. Children 3 - 6 years old
Children 3 - 4 years old: Initial dose: Take 10-15 mg/kg/day divided into 3 times/day. Increase dose: Take 25-30 mg/kg/day divided into 3 times/day. Children 5-6 years old: Take 25-30 mg/kg/day divided into 3 times/day. Patients with impaired renal function
Adjust dose of Gabanad 300 based on Creatinine clearance (CrCl)
CrCl dose 50 - 70 ml/min: Take 600 - 1200 mg/day divided into 3 times/day. Dose of CrCl 30 - 49 ml/min: Oral 300-600 mg/day divided into 3 times/day. Dose of CrCl 15 - 29 ml/min: 300 mg/day divided into 3 times/day. CrCl dose < 15 ml/min: 300 mg every other day, divided into 3 times/day. Dose for patients on peritoneal dialysis: Initial dose: 300-400 mg orally. Then: 200-300 mg every 4 hours on hemodialysis. 4.2. Pain due to peripheral neuritis: Adults
Initial dose Day 1: Take 1 tablet (300 mg)/time x 1 time/day. Day 2: Take 1 tablet (300 mg)/time x 2 times/day. Day 3: Take 1 tablet (300 mg)/time x 3 times/day. Thereafter: Increase gradually by 300 mg daily until a maximum dose of 6 tablets (1800 mg)/day is reached.
5. Note when using Gabanad 300:
Side effects encountered when using Gabanad 300
Treatment with Gabanad 300mg at high doses or for a long time, can cause side effects such as:
Common: Neurological signs such as fatigue, dizziness, edema, drowsiness, memory loss, loss of coordination, nystagmus. Young children may experience fussiness, feelings of euphoria or depression, oppositional attitudes, agitation... Digestive disorders such as dry mouth, indigestion, abdominal pain, diarrhea or constipation. Respiratory symptoms such as pharyngitis - pharyngitis, rhinitis, cough, pneumonia. Other symptoms such as rash, skin rash, joint pain, muscle pain, dizziness, vision loss, impotence, viral infection, leukopenia. Uncommon: Neurological symptoms such as depression, irritability or mental changes, memory loss, aphasia, decreased or lost libido, headache, mild paralysis. Digestive disorders such as loss or disturbance of taste, bleeding gums, stomatitis, weight gain, hepatomegaly. Cardiovascular symptoms such as palpitations, angina, peripheral vascular disorders, hypotension. Rare: Neurological symptoms such as personality disorder, motor dysfunction, psychosis, nerve palsy, hypersexuality. Gastrointestinal symptoms such as esophagitis, peptic ulcer, colitis, proctitis. Respiratory symptoms such as airway mucosal inflammation, cough, hoarseness, pulmonary hypoventilation, pulmonary edema. Visual symptoms such as lacrimation, retinopathy, itchy eyes, iritis. Other symptoms such as Stevens-Johnson syndrome, fever or chills, leukopenia, prolonged bleeding time, back pain, cartilage inflammation, osteoporosis. When detecting the above undesirable effects or any other abnormalities after taking Gabanad 300, patients and relatives should promptly inform their doctor or pharmacist about the use of Gabanad 300 or go to the hospital immediately. medical facility for prompt treatment.
Note the use of Gabanad 300 in subjects
Caution when using Gabanad 300 in the elderly, people with a history of mental disorders and patients with severe liver and kidney dysfunction, patients on dialysis . Pregnancy: According to the classification of the US Food and Drug Administration (FDA), the active ingredient Gabapentin in Gabanad 300 belongs to group C, there is evidence of a risk to pregnancy. Therefore, only use Gabanad 300 on subjects in necessary cases. Lactation: There are no data to determine the harmful effects of Gabapentin in breast milk. It is recommended that Gabanad 300 be used only after a risk-benefit assessment has been made. Drivers or machine operators often experience side effects such as dizziness, vision loss, dizziness, fatigue, drowsiness... after using Gabanad 300.
6. Gabanad 300 drug interactions:
Interactions with other drugs
The following drugs are not altered in pharmacokinetics when co-administered with Gabanad 300: Carbamazepine ; Phenytoin ; valproic acid ; Phenobarbital ; Diazepam ; Birth control pills containing Norethindrone with or without Ethinylestradiol. Gabanad 300 may be reduced bioavailability when taken with antacids, so Gabanad 300 should be taken at least 2 hours after taking the antacid. Drugs Probenecid, Cimetidine affect the secretion of drug Gabanad 300 in the kidney. The above is the basic information about the ingredients, uses, dosage and notes when using Gabanad 300. In order to bring the best treatment effect, patients and their relatives should carefully read the instructions for use. of the drug Gabanad 300, and strictly follow the treatment instructions of the doctor.
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