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Fytobact is an antibiotic indicated in respiratory, urinary - genital infections, peritoneal infections,... So what is the use of the drug and what should be noted when using it?
1. What is Fytobact?
Fytobact drug has main ingredients: Sulbactam sodium, Cefoperazone sodium. Ingredients Sulbactam:
Is a beta-lactam antibiotic that inhibits the beta-lactamase ring of bacteria. Sulbactam has very weak antibacterial activity, so it is often used in combination with another antibiotic. When bound to beta lactamase, sulbactam inactivates this enzyme, so it protects the antibiotics with beta lactam structure from being degraded to increase the effectiveness of the drug. The Sulbactam component of Fytobact is well absorbed from the gastrointestinal tract and parenteral route, diffuses well into tissues and body fluids, and is then eliminated mainly in the urine. Ingredients Cefoperazone:
Is a 3rd generation Cephalosporin antibiotic that kills bacteria through the mechanism of inhibiting cell wall synthesis, making bacteria unable to multiply. Cefoperazone is very stable against bacterial beta-lactamases. Therefore, it has a broad antibacterial spectrum against many strains of Gram-negative and Gram-positive bacteria. The drug is not absorbed from the gastrointestinal tract, is absorbed from the intravenous route, and is widely distributed in tissues and body fluids. Finally eliminated in bile and urine.
2. Indications of the drug Fytobact
Fytobact is indicated for the treatment of the following infections:
Respiratory tract infections: Bronchitis, pharyngitis, pneumonia,...; Gastrointestinal tract infections: hepatobiliary tract infections, peritonitis.; Pathology of urinary-genital infections: urethritis, cystitis,...; Infective endocarditis ; Infections secondary to trauma, after surgery; Septicemia; Meningitis .
3. Contraindications of Fytobact
Fytobact should not be used in cases of allergy to Sulbactam, Cephalosporin antibiotics or any other ingredient of the drug.
4. Note when using Fytobact 1g
Patients allergic to Penicillin use caution. Patients with bronchial asthma, allergic rash need to test the drug in a small amount before injecting. Check renal function before and during treatment with Fytobact in patients with severe renal impairment. Drugs that cross the placenta and breast milk should consider the benefits when used for pregnant and lactating women. Patients who eat poorly, have a nasogastric tube, are elderly, and have poor health when taking drugs should be carefully monitored.
5. Fytobact drug interactions
There is no specific evidence on the interaction of Fytobact with other drugs. However, when used in combination with any drug, it is necessary to have a doctor's prescription and monitoring. Alcohol, tobacco, and alcoholic foods can change the composition and effects of medications. Therefore, consult your doctor to choose the best food during the course of medication.
6. Dosage and usage
How to use:
Fytobact is prepared in the form of a powder for injection. Mix water with a sufficient amount of distilled water, injection or intravenous infusion. Dosage:
Dosage in adults: 1-2g x 2 times/day. For severe and long-term infections, the dose can be increased to 4g x 2 times/day. Dosage for children: 20-40mg/kg x 2 times/day. In severe and long-term infections, the dose can be increased to 160mg/kg twice a day.
7. Side effects of Fytobact
Some unwanted effects may be encountered when using Fytobact:
Digestive disorders, diarrhea, nausea, burning in the epigastrium. Pseudomembranous colitis. Hives. Anaphylaxis . Mild allergic reactions: skin rash, injection site reactions, itching,... Acute renal failure. Leukopenia, decreased blood prothrombin time. Thus, Fytobact is a combination antibiotic between Sulbactam and Cephalosporin group. The drug is widely indicated in most infectious diseases because of its broad antibacterial spectrum. However, abuse and prolonged use of the drug should be avoided because it can cause drug resistance in susceptible strains of bacteria.
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