Uses of Fudolac

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Fudolac drug is effective in the treatment of chronic hepatitis B in adults with the main ingredient is Entecavir. So how effective is the use of Fudolac? The notes when using Fudolac will be shared through the article below.

1. What is Fudolac?


Fudolac drug belongs to the group of drugs that treat parasites, anti-infectives, antivirals, antifungals. Fudolac is prepared in the form of film-coated tablets packed in aluminum blisters (1 blister, 2 blisters, 3 blisters, 6 blisters, 10 blisters x 10 tablets) and HPDE bottles (20 tablets, 30 tablets, 60 tablets and 100 tablets) tablets).
Fudolac medicine has the main ingredient of Entecavir (in the form of Entecavir monohydrate) 0.5mg and other excipients.

2. What are the effects of Fudolac?

Fudolac is used in the treatment of chronic hepatitis B virus infection in adults with evidence of persistent elevation of serum aminotransferases (ALT or AST), viral replication activity, or leprosy. tissue activity.

3. Dosage - How to take Fudolac


Patients should take Fudolac on an empty stomach about 2 hours after eating and 2 hours before the next meal. Recommended dosage of Fudolac for adults and adolescents 16 years of age and older with chronic hepatitis B virus infection, who have not used Nucleotide: 0.5 mg of Entecavir once daily. Recommended dose of Entecavir for adults and adolescents (16 years of age) with a history of hepatitis B virus infection while taking Lamivudine or with a Lamivudine resistance mutation: 1 mg Entecavir once daily. Patients with hepatic impairment: No dose adjustment of Entecavir is required in this case.

4. Contraindications to using Fudolac


Fudolac drug is not used for patients with hypersensitivity, history of allergy to Entecavir or to any of its ingredients.

5. Fudolac drug interactions


Fudolac is eliminated mainly by the kidneys, so co-administration of Entecavir with drugs that have the potential to decrease renal function or compete for active tubular secretion with Entecavir may increase serum concentrations of Fudolac. drugs that are co-administered or of Entecavir.
Co-administration of Adefovir dipivoxil, Tenofovir disoproxil fumarate and Lamivudine with Entecavir did not cause significant drug interactions. Co-administration of Entecavir with drugs that are excreted by the kidney or drugs that affect renal function has not been evaluated, therefore patients should be closely monitored for adverse effects of Entecavir when the drug is administered orally. used in conjunction with these drugs.

6. Side effects when using Fudolac for treatment


During the use of Fudolac, patients may experience some unwanted side effects such as:
Lactic acidosis Severe fatty liver disease Death Increases the risk of acute hepatitis B becoming Patients taking Fudolac should continue to closely monitor liver function for at least several months in patients who have discontinued anti-hepatitis B therapy. If the patient develops any suspicious symptoms. Due to the side effects of Fudolac, please notify your doctor or pharmacist immediately.

7. Precautions when using Fudolac


Before using Fudolac for treatment, patients should carefully consult the drug instructions or follow the instructions of the doctor, pharmacist. In addition, patients can refer to some of the following notes before using Fudolac for treatment.
In addition, the use of Nucleoside analogues alone or in combination with antiretrovirals has been reported to cause lactic acidosis, severe fatty liver disease, including fatal cases.
In addition, there are cases where patients have stopped anti-hepatitis B therapy, causing acute hepatitis B to worsen, including treatment with Entecavir. Patients should continue to have close clinical and clinical monitoring of liver function for at least several months in patients who have discontinued anti-hepatitis B therapy. If appropriate, anti-hepatitis inhibitor therapy can be initiated. Hepatitis B.
Heparin dose adjustment is recommended for patients with creatinine clearance <50ml/min, including those on hemodialysis or continuous outpatient peritoneal dialysis (CAPD). . The safety and efficacy of Heparin in liver transplant patients are unknown. If heparin treatment is necessary for a liver transplant patient who has been taking an immunosuppressive drug that may affect renal function, such as tacrolimus or cyclosporin, renal function should be checked before and during treatment with Hepariv. Cases to note before taking Fudolac: Elderly people, pregnant women, lactating mothers, children <15 years old, people with liver / kidney failure, patients allergic to Entecavir or any substance in the composition of the drug, the patient has myasthenia gravis, peptic ulcer, hepatic coma.

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