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Flazenca 750,000/125 is used in the treatment of acute, chronic or recurrent oral infections and the prevention of postoperative oral infections. The following article will help you understand the uses and uses of Flazenca effectively to treat oral diseases.
1. Uses and indications of the drug Flazenca
1.1. Flazenca drug ingredients Flazenca drug 750,000/125 includes two main ingredients:
Spiramycin with a content of 750000 IU. Metronidazole is 125mg. Dosage form: Flazenca powder for oral suspension.
1.2. Uses of the drug Flazenca With the above 2 main ingredients, Flazenca will help support the treatment of oral inflammatory diseases. Specifically as follows:
Spyramicin is a bacteriostatic agent belonging to the macrolide group - acting on the 50S subunit of bacterial ribosomes, so it has the ability to inhibit protein synthesis. Metronidazol is a bactericidal agent of the Imidazole group that is effective in the treatment of many diseases caused by anaerobic bacteria, parasites, and amoebae. The effect of Metronidazol is due to the fact that after penetrating the bacteria, it is reduced to toxic substances that disrupt the DNA of bacterial cells. Thus leading to the end result is the drug kills bacteria, parasites... 1.3. Adjustment of the drug Flazenca Flazenca drug 750,000/125 is used in a number of diseases such as:
Treatment of oral infections such as: Chronic, acute or recurrent bacterial infections. The drug has good effect in the treatment of tooth abscess, gingivitis, inflammation under the jaw, inflammation of the salivary glands ... Used to prevent infection after oral surgery. Treatment of other infections caused by susceptible organisms. 1.4. Contraindications to the drug Flazenca Contraindicated to use Flazenca 750.00/125 in the following cases:
The patient is allergic to spiramycin, Metronidazole or other antibiotics of the same group. People who are sensitive to one of the other components of Flazenca should not use the drug. Flazenca is not recommended for pregnant women, at least during the first 3 months of pregnancy. For women who are breast-feeding, in case it is absolutely necessary to use Flazenca for treatment, breast-feeding should be discontinued while taking the drug.
2. Dosage and how to use Flazenca
2.1. Dosage of Flazenca Using the right dose of Flazenca will help promote the full effect of the drug's anti-inflammatory and antibacterial properties. Depending on the subject, there will be a separate dose:
For people aged 15 years and over: Take 2 packs each time, 2-3 times a day. Children from full 10 years old to under 15 years old: Take 3 times a day, 1 pack/time. Children from full 5 years old to under 10 years old: 1 pack/time x 3 times/day. 2.2. How to take Flazenca Flazenca is taken orally. The patient uses enough water to mix Flazenca according to the prescribed dose into an oral suspension. Flazenca suspension after mixing should be drunk immediately to ensure effectiveness, can be taken before or after eating.
3. Notes when using the drug Flazenca
3.1. Side effects of the drug Flazenca can cause some common side effects when used as follows:
Patients may have diseases related to the gastrointestinal tract such as nausea, indigestion, diarrhea, not wanting to eat, The mouth has a metallic aftertaste. Allergic reactions: urticaria. Metallic taste in the mouth, glossitis, stomatitis. Moderate leukopenia, which is reversible upon discontinuation of the drug. Rare and associated with prolonged treatment: dizziness, loss of coordination, ataxia, colds, sensory and motor polyneuritis. Urinary: Urine is reddish brown. The side effects of Flazenca on other parts or the whole body are less common such as: nosebleeds, burning sensation, leukopenia, rash... Very rarely, Flazenca causes reactions. anaphylactic reactions, superinfection due to long-term use, epilepsy, polyneuropathy, dark urine... 3.2. Drug interactions In addition to causing side effects, patients should be aware that the following compounds may react with Flazenca to cause adverse health effects or reduce the effects of the drug. There are some precautions to use the drug as follows:
The effectiveness of oral contraceptives is lost when used in combination with Flazenca. Because Flazenca contains spiramycin, which reduces the concentration of Levodopa in the blood, it reduces the therapeutic effect of levodopa when taking these two drugs together. Flazenca enhances the effect of oral anticoagulants, especially warfarin. Therefore, it is recommended to monitor indicators such as prothrombin time to adjust the dose of anticoagulants. The interaction between Flazenca and Disulfiram can cause undesirable effects on the nervous system such as confusion, psychosis. Phenobarbitan increases metabolism of metronidazole component in flazenca, so the effectiveness of the drug is reduced. Flazenca when used concurrently with terfenadine, astemizol increases the risk of undesirable effects of these two drugs on the heart such as arrhythmia ... Therefore, these drugs should not be combined. Cimetidine reduces hepatic metabolism and prolongs the elimination half-life of Flazenca, leading to an increased likelihood of Flazenca side effects. The effect of vecuronium is increased when used with Flazenca. 3.3. Other notes Do not drink alcohol while using Flazenca, because there may be reactions between alcohol and drugs that are dangerous to health. To avoid the risk of lithium toxicity, Flazenca should not be used in patients with high blood levels of lithium (due to medication). Do not use Flazenca sachets with torn packaging or powder that is damp, lumpy, or discolored. 3.4. Note when using the drug for special subjects Pregnant women: In animals, metronidazole is not teratogenic and not toxic to the fetus. In a study on many pregnant women using Metronidazole in the first 3 months, there were no cases of malformations. Spiramycin crosses the placenta but the concentration of the drug in the placental blood is lower than in the mother's blood, Spiramycin does not cause harm to the pregnant woman.
Lactating women: Spiramycin and Metronidazole both pass into breast milk, avoid using the drug while breastfeeding.
With the sharing of the drug Flazenca will help the process of using the drug in patients effectively and safely. If you have more questions about the drug Flazenca, patients should refer to it for appropriate indications.
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