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Fasmuc drug has the main active ingredient Acetylcysteine and other excipients in a sufficient amount. The drug is used in the treatment of respiratory pathologies, specifically the treatment of mucolytic therapy in acute and chronic bronchopulmonary diseases accompanied by increased mucus secretion. Fasmuc is also used in high doses to effectively detoxify Paracetamol.
1. What is Fasmuc?
What is Fasmuc drug? Fasmuc drug has the main active ingredient is Acetylcysteine 200mg and other excipients in sufficient quantity. The drug is used in the treatment of respiratory pathologies, specifically the treatment of mucolytic therapy in acute and chronic bronchopulmonary diseases accompanied by increased mucus secretion. Fasmuc is also used in high doses to effectively detoxify Paracetamol.
Fasmuc drug is made in the form of capsules, suitable for direct oral use. Packing is a box of 10 blisters and each blister contains 10 capsules.
1.1. Pharmacokinetics of the active ingredient Acetylcysteine Main active ingredient Acetylcysteine is a mucolytic agent in the manner of thinning and dissolving phlegm. The drug acts on the gel phase of the mucus by cleavage of disulfur bonds of glycoproteins.
1.2. Pharmacokinetics of the active ingredient Acetylcysteine After oral administration, the active substance Acetylcysteine is rapidly absorbed from the gastrointestinal tract and is deacetylated by the liver to cysteine and subsequently metabolized. The active substance reaches peak plasma concentrations about 0.5 to 1 hour after oral therapeutic doses of 200 to 600 mg. Bioavailability with oral administration of Acetylcysteine is low and may be due to metabolism in the intestinal wall and first-pass metabolism in the liver. 1.3. Effect of active ingredient Acetylcysteine Acetylcysteine (N - acetylcysteine) is a N - acetyl derivative of L - cysteine, a natural amino - acid. Acetylcysteine is used as a mucolytic or expectorant and an antidote to paracetamol overdose. The active ingredient Acetylcysteine reduces the viscosity of sputum in purulent or non-purulent lungs by cleaving the disulfide bridge in the mucoprotein and facilitating the expulsion of sputum by coughing, postural drainage or by mechanical means. The active ingredient Acetylcysteine is also used topically for tear-free treatment. Acetylcysteine is used to protect against hepatotoxicity caused by overdose of the active ingredient Paracetamol. In the treatment of paracetamol overdose, a large amount of this metabolite is produced, since the main metabolic pathway (glucuronide and sulfate conjugates) becomes saturated. Acetylcysteine is converted to cysteine, which stimulates the liver to synthesize glutathione. Therefore, the drug Acetylcysteine can protect the liver if treatment is started within 12 hours after paracetamol overdose. Start detoxification treatment as soon as possible.
2. What diseases does Fasmuc drug treat?
Fasmuc drug is used in the treatment of diseases, as follows:
Treatment of reducing mucus, thin sputum in specific respiratory diseases such as acute or chronic bronchitis, bronchial obstruction to help ventilation airway. Use high doses of antidote when overdose of drugs containing the active ingredient Paracetamol.
3. Usage and dosage of Fasmuc
3.1. Dosage of Fasmuc If there is no other indication, the usual therapeutic dose, specifically as follows:
The therapeutic dose for adults and children over 7 years old is 200mg x 2-3 times/day. The therapeutic dose for children from 2 to 7 years old is 200mg x 2 times/day. Therapeutic dose for children under 2 years old: 100mg x 2 times/day. Dosage as an antidote in the treatment of paracetamol overdose: The initial dose is 140mg/kg, followed by a dose of 70mg/kg every 4 hours and a total of 17 times. Acetylcysteine is most effective when taken within 8 hours of an overdose of Paracetamol. After this time, the effect will decrease. However, starting overdose treatment more than 24 hours later may still be beneficial. 3.2. How to use Fasmuc drug Fasmuc drug is made in the form of capsules, suitable for direct oral drug use. You need to dissolve the medicine in water and then drink it. 3.3. Treatment of overdose/forgotten dose Fasmuc overdose case: There are currently no reports of harmful effects of Fasmuc when used in excess. You need to take the initiative to immediately contact the treating doctor and call an ambulance to the nearest hospital or medical station. In case of forgetting a dose of Fasmuc: Usually, drugs, including Fasmuc, can be taken within 1-2 hours compared to prescribed in the prescription. Unless the treating doctor has a strict rule about the time of use, the patient can take the medicine a few hours after forgetting it. However, if the time of taking the drug is too far from the time it should be taken, it is not advisable to take a supplement, because it can be dangerous to the body. You need to pay attention to strictly follow or consult your doctor before deciding to use the drug.
4. Undesirable effects of the drug Fasmuc
During the use of Fasmuc, you may experience some unwanted effects, specifically as follows:
Nausea, diarrhea, abdominal pain or digestive disorders. Canker sores, tinnitus, dry mouth, bitter mouth, metallic taste in mouth. Nausea, loss of appetite, paleness. Hypersensitivity reactions: Bronchospasm, angioedema, skin rash and pruritus, hypotension or occasionally hypertension may occur. Other undesirable effects: Flushing, nausea and vomiting, fever, fainting, sweating, joint pain, blurred vision, liver dysfunction, acidosis, convulsions, respiratory arrest or stop breastfeeding for children. When there are signs of suspicion due to unwanted effects of Fasmuc, you should take the initiative to immediately go to the hospital for timely treatment, avoiding long-term serious consequences.
5. Fasmuc drug interactions
Interactions of Fasmuc drugs may occur during use as follows:
Patients should take Tetracycline pills away from the time of taking drugs containing the active ingredient Acetylcysteine at least 2 hours. Fasmuc should not be used concurrently with cough suppressants, as it may cause severe mucus congestion due to decreased cough reflex. You should actively consult your doctor before combining use. Fasmuc contains the main active ingredient, Acetylcysteine, which can increase the vasodilator effect and inhibit platelet aggregation of nitroglycerin. The main active ingredient Acetylcysteine is a reducing agent – should not be combined with oxidizing agents.
6. Some notes when using Fasmuc
6.1. Contraindications of the drug Fasmuc People who are sensitive or hypersensitive to the main active ingredient is Acetylcysteine or one of the drug ingredients.
6.2. Note when using Fasmuc Drug Fasmuc use for pregnant or lactating women
For women who are pregnant or breast-feeding: It is best to be cautious if you are considering using the drug. Fasmuc for women who are pregnant or women who are breastfeeding. To make the right decision, you should consult your treating doctor before deciding to use the drug. Treatment of paracetamol overdose with drugs containing the active ingredient Acetylcysteine in pregnant women is effective, safe and has the ability to prevent liver toxicity in the fetus as well as for the mother. Fasmuc can be used by breast-feeding women. Using Fasmuc for those who drive and operate machinery
Undesirable effects when using Fasmuc have been reported to be dizziness, headache. Therefore, patients should not drive or operate machinery if they experience dizziness or lightheadedness. Above is all information about Fasmuc drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Fasmuc to treat diseases at home, because there may be unwanted side effects to health.
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