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Ezinapc is an antiallergic drug, used in cases of year-round or seasonal allergies. Let's learn the uses and how to use Ezinapc through the article below.
1. Uses of Ezinapc
Ezinapc 10mg is a drug belonging to the H1 antihistamine group, with the main ingredient being Cetirizine 10mg. Prepared in the form of film-coated tablets.Cetirizine is a strong antihistamine and has anti-allergic effects, but because it is the next generation, it usually has reduced side effects and does not cause drowsiness at usual doses.
Cetirizine has a selective antagonistic effect at the H-receptor and usually has negligible effect on other receptors. Therefore, the drug has almost no antagonistic effect on Acetylcholine and does not have an antagonistic effect on Serotonin, thereby reducing side effects on the nervous system. Cetirizine inhibits the initial phase of histamine-mediated allergic reactions and reduces the migration of inflammatory cells, reducing the release of mediators of the allergic reaction.
Therefore, Ezinapc is indicated for use in the following cases:
Seasonal allergic rhinitis and perennial allergic rhinitis: the drug helps relieve the symptoms of seasonal allergic rhinitis and allergic rhinitis. year round caused by various allergens (allergens) such as pollen, dust, animal dander, mold. Symptoms that medication can effectively treat include sneezing, runny nose, runny nose, itchy nose, itchy eyes, watery eyes, and red eyes in adults and children over 6 years of age. Chronic Idiopathic Urticaria: Ezinapc is indicated for the treatment of the cutaneous manifestations of chronic idiopathic urticaria in adults and children over 6 years of age without other complications. The drug also significantly reduced the appearance and severity, duration of the rash, and significantly reduced itching. Allergic conjunctivitis: Allergic conjunctivitis, conjunctivitis spring conjunctivitis can be used to relieve allergic conditions such as itchy eyes, watery eyes and red eyes in adults and children over 6 years old.
2. Contraindications of Enzinapc
Contraindicated to use Ezinapc in the following cases:
Do not use the drug in people with a history of allergy to cetirizine, to hydroxyzin or any other ingredient of the drug. End stage renal failure when creatinine clearance is less than 10 ml/min. Not for children under 6 years old, not for pregnant women. Use caution when using the drug in the following cases:
Drugs containing lactose: Should not be used in patients with galactose intolerance, lactase deficiency or glucose-glucose malabsorption. Medicines containing other ingredients such as Allura red, Ponceau 4R lake, Sunset yellow lake: May cause allergic reactions and rash, difficulty swallowing or breathing, swelling of lips, face, mouth or tongue. Caution should be exercised in those with a history of allergy to this substance.
3. Usage and dosage of Ezinapc
How to use: The drug is taken orally, the patient needs to take the drug with water can be taken at any time, with or without food.
Dosage:
Usual dosage for adults and children from 6 years of age and older: Take 1 tablet of Ezinapc 10mg and use it once a day.
Dosage for patients with liver failure: The oral dose should be reduced by half compared to normal people.
Dosage for patients with renal impairment: The dose should be adjusted according to the creatinine clearance as follows:
If the creatinine clearance is above 50ml/min, use as normal. If creatinine clearance is 30-49ml/min, use 5mg once daily. If creatinine clearance is less than 30ml/min, use 5mg once every 2 days. If creatinine clearance is less than 10ml/min or hemodialysis is required, do not use.
4. Side effects when using Ezinapc
What are the possible side effects when you take any medicine. Like other drugs, the use of Ezinapc can cause side effects including:
Common side effects: drowsiness, fatigue, dry mouth, sore throat, feeling dizzy, headache, nausea . Uncommon side effects: Anorexia or increased appetite, urinary retention, flushing, increased salivation. Rare: Some rare side effects may occur such as hemolytic anemia, thrombocytopenia, causing severe hypotension, anaphylaxis, hepatitis, cholestasis, glomerulonephritis. The above may not be completely exhaustive of the side effects of the drug, if you have other problems while taking the drug, you should stop taking it and inform your doctor.
5. Notes when using Ezinapc
Some notes you need to know when taking Ezinapc:
Tell your doctor if you have a history of allergy to any of the substances in the drug and your medical condition. When using the drug, if you see adverse or dangerous side effects, you need to notify your doctor or go to a medical facility for advice and treatment soon. When using the drug, some patients have drowsiness and dizziness. , so be very careful when driving, or operating machinery while in use to reduce the risk of accidents. Overdose can occur, manifesting mainly in adults as drowsiness and in children may be agitation. There is no specific treatment, so patients are usually prescribed gastric lavage and symptomatic treatment. If you forget to take a dose, you can take the missed dose whenever you remember, and if it is almost time for the next dose, skip the missed dose and do not take a double dose. Note in pregnant women, although not teratogenic in animals, but there are no adequate studies in pregnant women, so it is best not to use the drug during pregnancy. The drug is excreted in milk, so breastfeeding women should be careful when using it, it is best not to use it at the same time as breastfeeding. Avoid concomitant use of Cetirizine with alcohol and other CNS depressants, as it may potentiate the effects of these drugs. Note that in the case of short-lived allergic symptoms, you should stop taking the drug when the symptoms have disappeared or subsided. The drug should be stored in a cool place, the temperature is below 30oC, away from direct light and moisture. Keep the medicine out of the reach of children. Do not use when the medicine has expired or shows signs of deterioration. Hopefully through the article you have learned the effects of Ezinapc and the notes when taking it, if you have any questions, please consult your doctor or pharmacist for specific advice.
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