This is an automatically translated article.
Proton pump inhibitors are a group of drugs that are used a lot in diseases of the stomach such as gastroesophageal reflux disease or peptic ulcer disease. Rabeprazole is one of the active ingredients of this group of drugs and the main active ingredient of Eurorapi. So what effect does Eurorapi have and how should patients use it?
1. What is Eurorapi 20mg?
Eurorapi is a product of Globe Pharmaceuticals Ltd. Each box has only 1 blister x 10 tablets in the form of enteric coated tablets.
Eurorapi has the main active ingredient Rabeprazole Sodium 20mg with some excipients just enough for 1 tablet.
2. What are the effects of Eurorapi?
The active ingredient Rabeprazole in the formula of Eurorapi belongs to the group of Proton Pump Inhibitors, thus inhibiting the final stage of acid secretion through inhibiting the activity of the H+/K+ ATPase pump (also known as the H+/K+ ATPase pump). is the proton pump).The oral bioavailability of Rabeprazole in Eurorapi is approximately 52% equivalent to that of intravenous administration.
3. Indications of Eurorapi
Because of Rabeprazole's inhibitory effect on gastric acid secretion, Eurorapi 20mg is indicated in the following cases:
Gastroesophageal reflux disease (GERD); Peptic ulcer disease ; Zollinger Ellison syndrome. Contraindications Eurorapi : This product is not contraindicated for people who are hypersensitive to Rabeprazole and any of the ingredients in the drug.
4. Instructions on how to use Eurorapi
Patients need to carefully read the detailed information in the accompanying instruction sheet to understand the use and dosage of Eurorapi for the best treatment effect and minimize side effects. out.
How to use Eurorapi:
Eurorapi produces enteric coated tablets, so it is only used orally; The most suitable time to take Eurorapi is in the morning, before eating; When taking Eurorapi, the patient should swallow the tablet whole with a moderate amount of water, absolutely do not chew, crush and break; Note: When using Eurorapi to treat gastroesophageal reflux disease, an important issue is to adjust the appropriate nutrition to increase the effectiveness of the treatment.
Dosage of Eurorapi for adults is as follows:
Gastroesophageal reflux: 1 Eurorapi 20mg tablet per day for 4-8 weeks; Peptic ulcer disease: 1 Eurorapi tablet daily for a period of 4 weeks; Zollinger Ellison syndrome: 3 Eurorapi tablets orally per day, then adjusted according to disease status and patient response; No dose adjustment of Eurorapi is required in patients with mild to moderate impairment of liver and renal function. Safety when using Eurorapi in children under 18 years of age has not been established, so its use is not recommended in this population.
How to handle a missed dose or overdose of Eurorapi:
Missed dose: The patient needs to take the missed dose of Eurorapi as soon as he remembers. However, if it is too close to the time of the next dose, skip the missed dose, do not take a double dose to make up for it; Overdose: To date, there have been no reports of overdose cases when using Eurorapi in humans. However, it should be noted that the active ingredient Rabeprazole is strongly bound to plasma (about 96.3%), so hemodialysis will not be effective in overdose. If the patient has taken more than the recommended dose of Eurorapi, appropriate support and treatment of unusual symptoms should be given, and gastrointestinal lavage may be necessary if necessary.
5. Undesirable effects when using Eurorapi
When using Eurorapi 20, patients may experience some common side effects such as nausea, diarrhea, headache. However, most of these side effects are mild and transient.
Some less common side effects of Eurorapi:
Rhinitis, sore throat or flu symptoms, cough; Back pain not due to local causes; Dizzy; Insomnia; Bloating, abdominal pain, vomiting or constipation. If unusual symptoms occur while using Eurorapi, patients should immediately contact their doctor, pharmacist or go to the nearest hospital for examination, diagnosis and appropriate treatment measures.
6. Drug interactions of Eurorapi 20
Drug interactions to note during the use of Eurorapi 20:
Due to the inhibitory effect of acid secretion, Eurorapi will increase the pH in the stomach and may affect the bioavailability of some preparations containing active ingredients. Ketoconazole, Ampicillin, iron and iron-containing preparations; Eurorapi when used concurrently will prolong the metabolism and elimination time of Phenytoin and reduce the average AUC concentration of aluminum and magnesium-containing products; Rabeprazole in Eurorapi increases the concentration of Digoxin in the blood, thereby increasing the effect of Digoxin. To ensure safety and manage drug interactions effectively, the patient should inform the doctor about all the drugs, health foods being used as well as the medical history to be considered for interactions. may occur prior to treatment with Eurorapi.
7. Some notes when using Eurorapi and how to store it
Use of Eurorapi in pregnant women and nursing mothers:
There are no adequate studies on the effects of Eurorapi on the fetus, therefore this product is not indicated for pregnant women except for pregnant women. necessary cases; It is not known whether Rabeprazole in Eurorapi is excreted in breast milk, so it is best not to use the drug while breastfeeding. In case the use of Eurorapi is mandatory, the patient should stop breastfeeding. Use of Eurorapi drug for driving and operating machines
There have been no reports on the effect of Eurorapi 20 on the ability to drive and use machines. Therefore, patients can still use it but need to be cautious. Some other special notes of Eurorapi:
Caution when using Eurorapi in people with liver dysfunction; Eurorapi 20 can mask the symptoms of some malignancies such as stomach cancer, so patients should be examined to rule out these risks. Storage conditions for Eurorapi:
Store Eurorapi in cool, dry areas and avoid direct sunlight; Like any other medicine, Eurorapi should be kept out of the reach of children; Absolutely do not use Eurorapi after the expiry date printed on the package. Eurorapi has the main active ingredient Rabeprazole Sodium 20mg with some excipients just enough for 1 tablet. The drug belongs to the group of drugs called Proton pump inhibitors and is indicated for the treatment of gastric ulcers and gastroesophageal reflux disease. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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