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What is Eszol tablet, is it an antifungal drug? In fact, Eszol tablet is a popular anti-parasitic drug, with antifungal action with a broad spectrum of antifungal activity.
1. What is Eszol tablet?
Eszol tablet belongs to the group of drugs against infections, parasites, antivirals and antifungals, with the main ingredient being Itraconazole 100mg. The active ingredient Itraconazole has antifungal activity with a broad spectrum of fungi.
Eszol tablet is prepared in the form of film-coated tablets and is indicated for the treatment of the following cases:
Candidiasis of the mouth and oropharynx. Fungal infections of the skin, tinea versicolor between fingers, toes, fingernails, toenails, groin. Visceral fungal infections (Aspergillus, Blastomyces, Candida, Cryptococcus, Histoplasma, Paracoccidioides, Sporothrix). In addition, Eszol tablet is also used in the maintenance treatment in AIDS patients to prevent latent and recurrent fungal infections, prevent fungal infections when the patient has a long-term decrease in neutrophil count.
2. Usage and dosage of Eszol tablet
Eszol tablet is taken orally, take the drug with a sufficient amount of water and should be taken immediately after a meal.
Dosage of Eszol tablet is calculated according to 100mg tablets, specifically as follows:
Candida infections in the mouth and oropharynx: 1 tablet/time/day, the duration of treatment is 15 days. For patients with AIDS, neutropenia or organ transplant surgery, the dose is 2 tablets/time/day and the duration of treatment is also 15 days. Candida infections in the vagina and vulva: 2 Eszol tablets/time and use 2 times/day, only for 1 day; or can use 2 tablets / time / day but the treatment time is 3 days. Ringworm: 2 tablets/time/day, treatment time is 7 days. Ringworm: The usual dose is 2 Eszol tablets/time/day, the duration of treatment is 7 days; or can use 1 tablet / time / day but the duration of treatment is 15 days. For highly keratinized areas of the palms or feet, the dose should be 2 tablets / time and 2 times / day. Duration of treatment is 7 days or can be used at a dose of 1 tablet / time / day but the duration of treatment is 30 days. Toenail fungus: The duration of treatment with Eszol tablet is from 2 to 3 times, each treatment lasts 7 days with a dose of 2 tablets / time and 2 times / day, taking 2 tablets every morning and afternoon after eating. Each treatment should be spaced 3 weeks apart. Or can be treated continuously for 3 months but with a dose of 2 tablets / time / day. Visceral fungus: Depending on the type of fungus, the dose of Eszol tablet and the duration of treatment will be different. For Aspergillus fungus, use 2 tablets/time/day for 2-5 months, increase the dose to 2 tablets/time and 2 times/day if the disease is widespread. For Candida, the dose is 1-2 tablets/time/day and the duration of treatment is from 3 weeks to 7 months. For Cryptococcus ectoparasites, the dose is 2 tablets/time/day, the duration of treatment is from 2 months and can be up to 1 year. For Cryptococcus that causes meningitis, the dose of Eszol tablet is 2 tablets/time, 2 times/day and maintenance treatment with a dose of 2 tablets/time/day. For Histoplasmosis, use 2 tablets/time, 1-2 times/day and the average duration of treatment is 8 months. For the fungus Sporothrix schenckii, the dose is 1 tablet/time/day, the duration of treatment is 3 months. For the fungus Paracoccidioides brasiliensis, the dose is 1 tablet / time / day, the duration of treatment is 6 months. For Chromomycosis, use Eszol tablet dose from 1 to 2 tablets / time / day, the duration of treatment is 6 months. For the fungus Blastomyces dermatitidis, the dose is 1 tablet/time/day or 2 tablets/time but 2 times/day, the duration of treatment is 6 months. Although Eszol tablet overdose has not been recorded, if there are serious symptoms of overdose, the patient should be taken to a medical facility immediately or contact a doctor for timely treatment.
3. Side effects of the drug Eszol tablet
Eszol tablet may cause some unwanted side effects with the frequency of occurrence as follows:
Common: Gastrointestinal disturbances, abdominal pain, nausea, constipation, headache, dizziness. Uncommon: Eszol tablet rarely causes menstrual disorders, hepatitis, reversible elevations of liver enzymes, hypokalemia, edema, hair loss, hair loss (treatment for more than 1 month), allergic reactions, urticaria urticaria, exanthema, pruritus, Stevens Johnson syndrome, angioedema, Rare: Peripheral neuropathy. If you see any strange symptoms after taking Eszol tablet, the patient should immediately notify the doctor or go to the medical facility soon to be checked.
4. Some notes when using Eszol tablet
Do not use Eszol tablet in people with hypersensitivity to the drug's ingredients, pregnant women and patients taking astemizol, cisapride, midazolam, terfenadine, triazolam. Before using Eszol tablet to treat systemic candidiasis, the patient's sensitivity to Itraconazole should be checked. People with a history of liver disease or liver toxicity due to taking drugs should not use Eszol tablet. If the drug is used for more than 1 month, the patient should be checked for liver function periodically. Women who are pregnant or breastfeeding should not take Eszol tablets because of limited data on the drug in this population. Pregnant women should only take the drug when it is absolutely necessary because the fungal infection is serious and life-threatening, the use of the drug should be weighed by the benefits to the mother and the risks and risks to the fetus. pediatric. If women who are breast-feeding want to take the drug, they should stop breastfeeding. Although there are not many studies on Eszol tablet on driving and operating machines, caution should be exercised when performing these activities. Eszol tablet may interact with the following drugs: increased anticoagulant effect when used with the anticoagulant Warfarin; tinnitus and edema if used concurrently with calcium blockers; increases the concentration of HMG - CoA reductase inhibitors if used together and also causes myopathy and myositis. Eszol tablet also interacts and increases the concentration of Digoxin in the blood plasma if taken with Digoxin; cause severe hypoglycemia if used in combination with oral antidiabetic drugs; reduce drug bioavailability and reduce antifungal efficacy if used concomitantly with antacids, H2-receptor antagonists, Omeprazol and Sucralfate; Decreased plasma concentrations of the drug if co-administered with enzyme inducers. Before taking Eszol tablet, patients need to prepare a list of current or previous medications, including prescription or non-prescription drugs, dietary supplements and herbal products. The use of the drug Eszol tablet is antifungal. With a broad spectrum of antifungal activity, Eszol tablet is used in the treatment of fungal infections of the mouth, throat, skin, internal organs, ...
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