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Dovamed eye drops are used in the active treatment of eye diseases such as allergies, uveitis... The main ingredients are Ciprofloxacin and Dexamethasone. Read the article below to get more useful information about this drug.
1. Uses of Dovamed
Each ingredient in Dovamed has its own uses. Specifically:
Ingredients Ciprofloxacin is a new active ingredient in the quinolone group but has broad-spectrum bactericidal ability and strong activity. At the same time, Ciprofloxacin interferes with the growth of bacteria by blocking information from the chromosomes (genetic material) necessary for normal bacterial metabolism. It is also thanks to the mechanism of cran information from chromosomes that this component is not resistant to parallel with other antibiotics that do not belong to the group of gyrase inhibitors.
Ciprofloxacin can be combined with beta-lactam antibiotics and aminoglycosides. however, the effect produced was only complementary or unchanged under in-vitro conditions. But in-vivo this combination has a synergistic effect (as in combination with azlocillin), especially in neutropenic animals.
Some drugs can be combined with Ciprofloxacin such as:
Pseudomonas: azlocillin, ceftazidime. Streptococci: mezlocillin, azlocillin and other potent beta-lactam antibiotics. Staphylococci: beta-lactam antibiotics, especially isoxazolylpenicillin, vancomycin. Anaerobic bacteria: metronidazole, clindamycin. Regarding absorption, Ciprofloxacin is absorbed from the gastrointestinal tract. The composition is partly affected by food, as evidenced by the presence of food or antacids, the drug will be absorbed slowly.
Regarding distribution, when entering the body, ciprofloxacin will reach the maximum concentration in the blood after about 1 - 1.5 hours. This component is distributed in high concentrations at the site of infection and takes 3 to 5 hours to half-life. Ciprofloxacin excretion time during the first 24 hours. Components Ciprofloxacin is metabolised in the liver
In addition to Ciprofloxacin, Dovamed also contains the main ingredient, Dexamethasone. This ingredient has the main effect of anti-inflammatory, anti-allergic, immunosuppressive. Dexamethasone's mechanism of action is to bind to receptors in the cell, translocate to the cell nucleus, and there affect a number of genes to be translated.
Dexamethasone is 30 times more anti-inflammatory than hydrocortisone and 7 times more effective than prednisolone.
About absorption: This ingredient is absorbed through the gastrointestinal tract and at the drug site, especially in the liver and kidney...
About distribution: The drug can pass through breast milk and placenta. pregnant. Therefore, pregnant and lactating women should exercise caution when taking the drug. The extent of metabolism of Dexamethasone through the liver is slow.
Elimination: Dexamethasone is eliminated in the urine and half-life is 36 - 54 hours.
The combination of Ciprofloxacin and Dexamethasone is effective for Dovamed in the following cases:
Eye allergies Recurrent ulcers caused by toxic or allergic reactions Heat or chemical burns of the eyes Acute anterior uveitis Anterior uveitis Chronic Iritis Blepharitis Eye disease caused by Herpex zoster. However, in some cases below, the drug is not indicated for prescription:
Patients with hypersensitivity to Ciprofloxacin and Dexamethasone or any of its ingredients. Patients with a history of hypersensitivity to quinolones Ocular tuberculosis Ocular fungal disease
2. Dosage and usage of Dovamed
Depending on the purpose of treatment, the patient's condition, the doctor will prescribe different doses of drugs, specifically:
Corneal ulcer disease: Put 2 drops of Dovamed in the eye with corneal ulcer every 15 minutes for a period of time. the first six hours. For the remainder of the first day still instill 2 drops in the affected eye but every 30 minutes. Day 2, every 1 hour will drop 2 drops of medicine. From the 3rd to the 14th day, 2 drops of the drug will be instilled after about 4 hours. Treatment of bacterial conjunctivitis: Instill 1 or 2 drops into the conjunctival sac every 2 hours while awake, for 2 days; Instill one or two drops into the conjunctival sac every 4 hours while awake, for the next 5 days. Some notes when instilling Dovamed in the eyes:
Clean hands with soap and water before applying Dovamed eye drops. Immediately after instillation, close the lid of the vial tightly, avoiding contact with air and dust. Do not share eye drops with other sick people to avoid infection. In case of drug overdose can be treated by using warm water to wash the eyes.
3. Dovamed side effects
Dovamed drug is well tolerated, but during the treatment of the disease, the drug can still cause some adverse effects such as: local discomfort or burning, white crystalline precipitate...
Some other less common side effects such as: hard eyelids, scabs/crystals, foreign body sensation, itching, corneal congestion... More rare side effects such as: conjunctivitis, allergic reactions allergies, eyelid swelling, lacrimation, photophobia, corneal infiltration, nausea, and decreased visual acuity. When these unusual signs appear, the patient should notify the doctor for prompt treatment. Note that do not arbitrarily use other drugs to treat side effects of Sotramezol.
4. Dovamed drug interactions
Currently, there are no specific drug interaction studies of Dovamed. However, you should not subjectively combine drugs without a doctor's prescription. At the same time, to avoid drug interactions, patients should actively make a list of all medications they are taking (including prescription, non-prescription, herbal and dietary supplements) and show it to their doctor or pharmacist. view and advise.
5. Be careful when taking Dovamed
To use the drug safely, patients need to "take to heart" some of the following notes:
Dovamed eye drops should be used with caution in children under 1 year of age. Parents are not allowed to self-medicate their children without consulting a doctor. Carefully read the instructions on the storage of the drug on the box and read the instructions for use of the medicine. Store the medicine in a cool, dry place, avoid direct sunlight or high temperature, it can convert the ingredients in the medicine. Above is information about the uses, dosage and precautions when using Dovamed. To ensure safety for health and maximize the effectiveness of treatment, patients need to use Dovamed exactly as directed by their doctor. Note, Dovamed is a prescription drug, patients absolutely cannot use it without a prescription from a specialist.
