Uses of Dorocetam 800

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1. What is Dorocetam?

The main active ingredient of Dorocetam 800 is Piracetam 800mg and the system of excipients includes: Microcrystalline cellulose PH 101, Povidone K30, croscarmellose sodium, Magnesium stearate, Colloidal silicon dioxide A200, Hydroxypropyl methylcellulose 15cP, Hydroxypropyl methylcellulose 6cP , Polyethylene glycol 6000, Talc, Titanium dioxide.
Dorocetam 800 medicine is made in the form of white film-coated tablets, oval, mo-faced, one side engraved with lines, edges and healthy tablets Dorocetam 800, white inside.

2. Indications of Dorocetam 800

Dorocetam 800 is indicated in adult patients with myoclonic tremor of cortical origin, regardless of etiology, who should be used in combination with Dorocetam 800 with other anticonvulsant therapies:
Damage brain injury, symptoms of brain surgery and brain injury: psychosis, stroke, hemiplegia, ischemia; Peripheral and central brain disorders: dizziness, headache, severe delirium; Brain disorders: coma , symptoms of senility, impaired consciousness; Cerebrovascular accident, CO poisoning and sequelae; Declining cognitive function and chronic sensory neuropathy in the elderly; Difficulty learning in children, chronic alcoholism, myoclonic tremor.

3. Contraindications of Dorocetam 800

Hypersensitivity to Piracetam or any component of Dorocetam 800 or other derivatives of pyrrolidone; Patients with severe renal impairment - creatinine clearance < 20 ml/min); Patients with cerebral hemorrhage; Patient has Huntington's chorea.

4. Dosage of Dorocetam 800

Always take Dorocetam 800 at the correct dose prescribed by your doctor, the reference dose is as follows:
Dorocetam 800 daily dose starts at 7.2 g, then increases by 4.8 g every 3-4 days to Maximum dose is 24g, divided into 2-3 times. Combination therapy of Dorocetam 800 with other anticonvulsants should be maintained at the same dose, depending on clinical benefit, the dose of the combination drug should be reduced. Elderly: Dosage adjustment of Dorocetam 800 is recommended in elderly patients with impaired renal function. During long-term dorocetam 800 treatment in the elderly, regular assessment of creatinine clearance is required to adjust the dose accordingly. Patients with hepatic impairment: No dose adjustment of Dorocetam 800 is required in patients with hepatic impairment only. How to use: Dorocetam 800 is used orally, can be taken with or without food, should divide the daily dose from 2 to 4 small doses.
In case you forget to take a dose of Dorocetam 800: Take it as soon as you remember, if it is almost time for your next dose of Dorocetam 800, skip the missed dose and take the next dose at the usual time, do not take it. double dose to make up for the missed dose.
No adverse effects related to Dorocetam 800 overdose have been reported with piracetam. The highest dose of Dorocetam 800 overdose with piracetam is 75g. A case of diarrhea with abdominal pain when taking a daily dose of 75g Piracetam may be related to a high dose of sorbitol in another drug used.

5. Dorocetam 800 side effects

Bleeding disorders; Anaphylactic reactions, hypersensitivity; Stress; Depression ; agitation, anxiety, hallucinations; Hyperactivity; Sleepy; Loss of balance, worsening seizures, headache, insomnia; Dizzy ; Abdominal pain, diarrhea, nausea, vomiting; Angioedema, dermatitis, pruritus, urticaria; Attenuate; Weight gain.

6. Drug interactions of Dorocetam 800

Piracetam does not inhibit the human liver cytochrome P450 enzyme Thyroid hormone: Confusion, irritability and sleep disturbance have been reported during concomitant treatment of Piracetam with thyroid serum (T3 + T4). Acenocoumarol: In a single-blind study published in patients with severe recurrent venous thrombosis, the dose of Piracetam 9.6g/day did not alter the dose of Acenocoumarol required to achieve an INR of 2.5-3.5, but Compared with the effect of Acenocoumarol when used alone, the addition of Piracetam 9.6g/day significantly reduced platelet aggregation, beta-thromboglobulin release, fibrinogen levels, Von Willebrand factors, whole blood and plasma viscosity. Antiepileptics: A daily dose of 20 g of piracetam for 4 weeks did not alter peak and trough concentrations of antiepileptic drugs (carbamazepine, phenytoin, phenobarbital, valproate) in epileptic patients on stable doses. Alcohol: Concomitant administration of piracetam with alcohol did not affect the serum concentration of piracetam and alcohol concentration was not altered by an oral dose of 1.6 g of piracetam.

7. Be careful when using Dorocetam 800

Dorocetam 800 affects platelet aggregation: Due to the effect of piracetam on platelet aggregation, caution should be taken when administering Dorocetam 800 to patients with major bleeding, patients at risk of bleeding such as sugar ulcers gastrointestinal disorders, potential hemostasis disorders, a history of hemorrhagic cerebrovascular accident, patients requiring major surgery including dental surgery, and those taking anticoagulants or antiplatelet drugs bridge; Renal Impairment: Dorocetam 800 is eliminated by the kidneys and therefore the same dose should be used in the case of renal failure; Elderly: When long-term treatment with Dorocetam 800 in the elderly, it is necessary to regularly assess the creatinine clearance to adjust the dose accordingly if necessary; Withdrawal: Abrupt discontinuation of Dorocetam 800 should be avoided as this may cause myoclonus or generalized convulsions in epileptic patients. Warning regarding excipients: Dorocetam 800 contains approximately 98.89 mg of sodium per 24 g of piracetam, so it should be considered when using Dorocetam 800 in patients on a sodium diet. Use of Dorocetam 800 in pregnancy and lactation:
Piracetam should not be used during pregnancy unless clearly needed, when the benefits outweigh the risks. Since Piracetam is excreted in human milk, Dorocetam 800 should not be used while breastfeeding or breast-feeding should be discontinued while being treated with Dorocetam 800. Ability to drive, operate machinery: with a dose of Dorocetam 800 from 1.6 - 15g per day increases hyperactivity, drowsiness, nervousness and depression. There have been no reports of ability to drive with doses of Dorocetam 800 of 15 to 20 g per day; however, piracetam should still be used with caution in patients who intend to drive or use machines.

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