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Dolarac 500mg belongs to the group of pain relievers, antipyretics, non-steroidal anti-inflammatory drugs whose main ingredient is Mefenamic acid, which participates in the process of preventing the formation of prostaglandin precursors. The drug is often indicated for the treatment of pain symptoms in rheumatoid arthritis, muscle pain, menstrual pain or other types of pain during movement injuries.
1. What does Dolarac 500 do?
Dolarac's main ingredient is Mefenamic acid, a non-steroidal anti-inflammatory drug of the Fenamate group, which has analgesic, anti-inflammatory effects and inhibits the synthesis of prostaglandins. Dolarac is usually indicated in the following cases:Relief of mild to moderate neuropathic pain symptoms; Headaches, migraines, pain from trauma; Postpartum pain, pain after surgery; Toothache, pain and fever followed by inflammation, dysmenorrhea, menorrhagia; Pain due to spasm or pain in the lower abdomen; Rheumatoid arthritis (including Still's disease), osteoarthritis, and myalgia. Contraindications of Dolarac 500:
Patients with hypersensitivity to any of the components of Dolarac; Patients with inflammatory bowel disease; Patients with a history of gastrointestinal bleeding or gastric perforation due to previous NSAID use; Patients with progression or history of recurrent gastric or duodenal ulcer/bleeding; Patients with severe heart failure, liver failure and kidney failure; Mefenamic acid should not be used in patients who have had a hypersensitivity reaction to aspirin or ibuprofen because of the risk of cross-sensitization; Treatment of pain after coronary artery bypass graft (CABG) surgery; Pregnant women are in the last 3 months of pregnancy.
2. Dosage of the drug Dolarac 500
Depending on the subject and the goal of treatment, the dose of Dolarac 500mg will be different, specifically as follows:
For adults:
Use 1 tablet 500mg x 3 times/day; Patients with menorrhagia take the drug on the first day of heavy bleeding and continue taking Dolarac according to response; Patients with dysmenorrhea take the drug at the onset of abdominal pain. For the elderly (over 65 years old):
Dolarac dose is the same as for adults; Elderly patients are at increased risk of serious adverse effects when taking Dolarac, so the lowest effective dose should be used at initiation and for the shortest duration; Mefenamic acid should be used with caution in elderly patients with dehydration and renal disease; Renal failure and proctitis have been reported in elderly patients who did not discontinue mefenamic acid after the onset of diarrhea. For children:
Children under 12 years of age should take mefenamic acid suspension (50 mg/5 ml); Should be taken with or after meals at the lowest effective dose for the shortest time to control symptoms.
3. Dolarac side effects:
In some patients when using Dolarac 500 may experience side effects such as:
Nausea, vomiting, diarrhea, abdominal pain, indigestion; rash, itching, headache, dizziness; Depression ; Convulsions in overdose should therefore be avoided in epileptic patients; May make asthma worse.
4. Be careful when using Dolarac
Some general notes when using Dolarac include:
During long-term treatment with Dolarac, special attention should be paid to liver dysfunction, rash, blood disorders or diarrhea; Caution should be exercised when mefenamic acid is co-administered with other NSAIDs including COX-2 inhibitors; Long-term use of any pain reliever can make a headache worse; Use caution when using the drug for patients with dehydration and kidney disease, especially the elderly; Dolarac should be used with caution in patients with acute gastrointestinal ulceration, in patients with existing or history of bronchial asthma; Mefenamic acid may decrease fertility in women and is not recommended in women trying to conceive; Dolarac should be used with caution in patients with epilepsy.
5. Doralac 500 . Drug Interactions
Dolarac may increase the effects of anticoagulants such as Warfarin. Prothrombin time should be monitored when mefenamic acid is co-administered with oral anticoagulants; Dolarac may decrease renal clearance of lithium and increase plasma concentrations of lithium; Avoid concurrent use of two or more NSAIDs, including Aspirin, as this may increase undesirable effects; Selective serotonin reuptake inhibitors increase the risk of gastrointestinal bleeding when co-administered with Dolarac; Co-administration of Dolarac may decrease the effectiveness of antihypertensive drugs and diuretics. Diuretics may increase the nephrotoxicity of NSAIDs. Above is information about uses, dosage and precautions when using Doralac 500. To ensure safety for health and maximize the effectiveness of treatment, patients need to take Doralac 500 exactly as directed by their doctor.
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