Uses of DigoxineQualy

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1. What is the use of DigoxineQualy?

Each DigoxineQualy 0.25mg tablet has the main ingredient Digoxine 0.25mg and excipients. Digoxin is a cardiac glycoside with the mechanism of action is to increase the force of myocardial contractility, causing positive muscle fiber contraction. Since then, it reduces pulse rate in patients with heart failure, because increasing myocardial contractility improves circulation. In addition, Digoxin also reduces heart rate through stimulation of the parasympathetic nerve (stimulation of the vagus nerve) and slowing conduction in the atrioventricular node.
Indications to use DigoxineQualy:
Treatment of heart failure, atrial fibrillation, atrial flutter, especially when there is too fast ventricular rate; Treatment of paroxysmal supraventricular tachycardia. Contraindications to the use of DigoxineQualy:
Patients with hypersensitivity to Digoxine or other components of the drug; People with intermittent complete heart block; Patients with 2nd degree atrioventricular block; Patients with obstructive hypertrophic cardiomyopathy; Patients with atrioventricular dysfunction due to Wolff - Parkinson - White syndrome; Children under 5 years old.

2. How to use and dose DigoxineQualy

Usage: Orally. Patients should take DigoxineQualy with 1 glass of filtered or boiled water. Patients should not take the medicine with other liquids (carbonated soft drinks, fruit juices) without the doctor's permission. The best time to take the medicine is after eating.
Dosage: Depending on the patient's health condition. Specifically:
Dosage for adults:
Initial dose: Take a dose of 2 - 4 tablets/day, divided into several times; Maintenance dose: Take 1-2 tablets/day, divided into 1-2 times. Dosage for children:
During the initial treatment, children take 1 dose/day, the dose depends on the child's weight: Children over 24kg: Use a dose of 7mcg/kg; Children 12 - 24 kg: Use dose 10mcg/kg; Children 3 - 6kg: Use a dose of 20mg mcg/kg; Children under 3kg: Use dose 15mcg/kg. During maintenance therapy: It is recommended to take the drug every 8 hours, taking a dose equal to 1⁄3 of the original dose. Missed dose: If you miss a dose of DigoxineQualy, you should take it as soon as you remember. In the event that it is almost time for the next dose to be remembered, the patient should skip the missed dose, continue with the previous scheduled dosing schedule, do not take 2 doses at the same time.
Overdose: Symptoms of overdose of DigoxineQualy include: Muscle weakness, mental confusion, adrenal insufficiency, increased appetite, increased blood sugar,... In addition, prolonged drug overdose also has can cause dizziness, tinnitus, depression, low blood pressure, even death. When seeing the above abnormal symptoms, the patient should immediately go to the nearest medical facility for timely symptomatic treatment and supportive treatment.
If symptoms are not important, just stop taking DigoxineQualy, use activated charcoal, cholestyramine or colestipol to promote glycoside clearance, use potassium salts if patient has hypokalemia and decreased renal function, do not use if there is hyperkalemia or complete heart block. Other drugs used to treat arrhythmias caused by Digoxin toxicity are procainamide, Lidocaine, Phenytoin, and Propranolol. Alternatively, a chelating agent such as calcium-binding EDTA can be used to treat arrhythmias caused by digoxin toxicity. In the event of a life-threatening overdose of Digoxin, the patient should be given intravenous injection of the anti-Digoxin-resistant Fab drug.

3. DigoxineQuality side effects

When using DigoxineQualy, patients may experience some side effects such as:
Common: Digestive disorders, nausea, vomiting, loss of appetite; Uncommon: Bradycardia, ventricular arrhythmias, atrioventricular block, atrial or nodal extrasystoles, double, triple, ventricular arrhythmias, atrial tachycardia with atrioventricular block, headache, somnolence, dizziness, dizziness, fatigue, diarrhea, food intolerance, abdominal pain, lethargy, disorientation, blurred vision, halo, double vision, flashes of light, yellow or green vision, photophobia , hyperkalemia with acute poisoning, neuralgia,... When experiencing side effects of DigoxineQualy, the patient should immediately notify the doctor and be hospitalized for timely treatment.

4. Precautions while using DigoxineQualy

Before and during the use of DigoxineQualy, patients should be aware:
Hypokalemia may increase digitalis toxicity. Therefore, serum potassium should be checked before initiating therapy, correcting hypokalemia if present. After that, regularly check blood potassium during drug administration; Reduce the dose of DigoxineQualy for elderly patients, hypothyroidism, respiratory failure, hypercalcemia, progressive heart failure, liver failure, renal failure, hypokalemia, who have used 1 drug before starting treatment. other digitalis; There should be close supervision of a doctor when using DigoxineQualy for people with increased blood calcium levels, decreased blood potassium levels; When using DigoxineQualy, the patient's electrocardiogram should be monitored in case of first degree atrioventricular block; Do not use DigoxineQualy tablets for children under 5 years old; There are data on babies born with low birth weight or premature birth when mothers use DigoxineQualy during pregnancy. Therefore, its use in pregnant women is not recommended. If you really need to take medicine, it is necessary to weigh the benefits and risks, use the drug exactly as prescribed by the doctor; DigoxineQualy may pass into breast milk, but there is no information on adverse effects in a nursing infant. However, women who are breastfeeding should not self-medicate without a doctor's prescription; DigoxineQualy drug acts on the central nervous system, causing visual disturbances. Therefore, caution should be exercised when administering the drug to people who drive or operate machinery.

5. DigoxineQuality drug interactions

Drug interactions that may affect the therapeutic effect of DigoxineQualy or other drugs; increase side effects. Therefore, before taking the drug, the patient should inform the doctor about the medicines he is taking and has recently taken. At the same time, patients should not self-medicate, stop taking or change the dose of any medicine without the permission of the doctor.
Some of DigoxineQualy's drug interactions include:
Caution when combining DigoxineQualy with sennosides, as it may increase the risk of Digoxin toxicity; Use caution when combining DigoxineQualy with Suxamethonium because it may increase blood potassium; Caution should be exercised when DigoxineQualy is co-administered with antacids, phenytoin, neomycin, salbutamol, rifampicin, adrenaline because it may reduce the bioavailability of DigoxineQualy. When using DigoxineQualy, patients should strictly follow the doctor's instructions on the way and dose of the drug. If you have any questions, you should contact your doctor for answers, do not change the dose on your own to avoid the risk of adverse reactions.
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