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Destidine is a new generation of antihistamines, with long-lasting effects and limited side effects on the central nervous system such as drowsiness compared to the previous generation. Let's learn about the use of Destidin through the article below.
1. What is the effect of Destidin?
Destidine has the active ingredient Desloratadine 5mg. Prepared in the form of tablets. Desloratadine is a second generation antihistamine. When the body is exposed to an allergen, the body responds by producing chemical mediators, of which histamine is a chemical mediator involved in the main mechanism that produces allergy symptoms. . Destidine drugs have selective inhibitory effects on peripheral histamine H1 should reduce disease symptoms and this drug almost does not cause drowsiness.When studying the drug, it was found that when taking 5mg of Desloratadine, it showed that this drug has an anti-histamine effect after taking it for 1 hour; This effect of the drug can last 24 hours.
2. Indications and contraindications when taking the drug Destidine
Indications:
The drug is indicated for symptomatic treatment in allergic diseases including:
Relief of symptoms of seasonal allergic rhinitis, year-round allergic rhinitis such as sneezing, runny nose, itchy nose, stuffy nose, cough... Allergic conjunctivitis such as eye irritation, watery eyes, red eyes, itching. Relief of symptoms of acute or chronic idiopathic urticaria. Contraindications:
Do not use Destidine in the following cases:
Hypersensitivity to drug components or a history of hypersensitivity to loratadine. Children under 6 years old.
3. Dosage and how to take Destidine
How to take Destidine:
It is taken by mouth, with or without meals, to help relieve allergy-related symptoms.
Drug administration in intermittent allergic rhinitis (symptoms present < 4 days/week or symptoms present < 4 weeks) should be based on current assessment and treatment should be discontinued when symptoms are resolved. symptoms, can be re-treated when symptoms reappear. In persistent allergic rhinitis (when symptoms appear > 4 days/week and symptoms persist > 4 weeks), treatment can be continued for the duration of allergen exposure. Dosage of Destidine:
For adults and children over 12 years: The recommended dose is 5mg once a day. Children 6 to 11 years of age: The recommended dose is 2.5mg given once daily. For patients with hepatic or renal impairment, the starting dose is 1 tablet of Destidine 5 mg. Overdose, missed dose:
Overdose In a clinical study in adults and adolescents using desloratadine up to 45 mg i.e. 9 times the clinical dose, no clinical manifestations of overdose were observed. . However, you run the risk of experiencing symptoms such as side effects from medications. Should go to the hospital to remove the unabsorbed drug. Especially for children under 2 years of age, there have been reports of children dying from an overdose of antihistamines, so be very careful when using this object.
Missed dose: If you miss a dose while on medication, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time.
4. Destidine side effects
When taking drugs besides the effect of the drug, unwanted effects may also occur. Side effects of Destidine include:
Rare: feeling tired, dry mouth, headache. Very rare: skin rash, anaphylaxis, urticaria, edema, dyspnea and elevation of liver enzymes including bilirubin. These side effects are rare but dangerous, so seek medical attention as soon as you experience them. Uncommon side effects: nausea, fatigue, dizziness, drowsiness, sore throat, slow digestion and muscle pain. Destidine can cause other side effects when used. If you have any of the above or other side effects that you think are side effects of Destidine, consult your doctor or pharmacist.
5. Notes and cautions when using Destidin
Before taking the medicine you should talk to your doctor about a history of allergies to the drug or any of its ingredients.
Caution when used for subjects such as:
Pregnant women: Drugs used during pregnancy can cause adverse effects such as miscarriage, teratogenicity, fetal malformation... to any person. any stage of fetal development, especially during the first trimester of pregnancy. Therefore, it is best not to use this medicine for pregnant women. In cases where it is necessary to use it, it is necessary to consult your doctor carefully before making a decision. Desloratadine should only be used during pregnancy if clearly needed. Lactation: Desloratadine can pass into breast milk and pose a risk of harm to a nursing infant. Therefore, a decision should be made whether to discontinue nursing or to discontinue desloratadine based on the importance of the drug to the mother. Use in Children: The safety and effectiveness of desloratadine in pediatric patients under 6 years of age with this drug have not been established. Use of drugs for the elderly: Choosing the dosage of this drug for an elderly patient should be cautious, because the elderly may have other medical problems, liver and kidney disease... Operators Hook: Because the drug causes dizziness and drowsiness, you need to avoid this activity during the first time taking the drug. Until you know how the drug affects you. This medicine is a symptomatic treatment, you try to find the allergen and stay away from it. It can bring the most effective toits and limit the use of drugs.
Drug interactions: When concomitant use of destidine drugs increases peak plasma concentrations of drugs such as antibiotics erythromycin, ketoconazole, antibiotics azithromycin, cimetidine. It may be necessary to change the dose of the medicine to avoid harming the body. Desloratadine may increase the concentration and effect of anticholinergics, CNS depressants, selective serotonin reuptake inhibitors.
When using destidine with foods or alcohol, beer, tobacco... can affect the phenomenon of antagonism or synergism with the drug. Care should be taken when using the drug with alcohol, beer and certain foods.
Storage: Store the medicine in a cool, dry place and be careful not to leave it out of the reach of children, to keep it away from pets. Before taking Destidin, you need to check the expiry date of the medicine, especially with the medicines you have at home.
Hopefully with the above information you know the uses, how to use and note when using Destidine. If you have any further questions, you should consult your doctor or pharmacist directly.
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