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Deslora is a medicine used in the treatment of allergic rhinitis and chronic idiopathic urticaria. So what does Deslora drug work, and how to use this drug?1. What are the effects of Deslora?
Deslora medicine is an antihistamine drug, which is made in the form of film-coated tablets, with the main ingredient including Desloratadine 5mg. Desloratadine is a metabolite of loratadine, which selectively antagonizes peripheral histamine H1 receptors. Thereby inhibiting the binding of histamine in the circulation to the receptor sites.Deslora does not prevent the release of histamine. Desloratadine inhibits the smooth muscle contractions of the respiratory, digestive, and circulatory systems, and reduces the secretion of activated histamine from the lacrimal and salivary glands, thus having an anti-inflammatory effect.
Deslora drug also works to reduce capillary permeability, so it reduces itching and reduces inflammation caused by allergies. Because desloratadine does not cross the blood-brain barrier and it has only a selective effect on peripheral histamine receptors, Deslora has only a low sedative and anti-sympathetic effect.
Deslora drug is indicated in the following cases:
Allergic rhinitis: Deslora drug is effective in reducing the symptoms of seasonal allergic rhinitis and chronic allergic rhinitis in patients from 12 years of age. or more, those symptoms include: Sneezing, runny nose, itching, stuffy nose, accompanied by eye irritation, watery eyes, and red eyes. Chronic idiopathic urticaria: Deslora is effective in reducing the symptoms of pruritus and erythema in patients 12 years of age and older with chronic idiopathic urticaria. Deslora drug is contraindicated in the following cases:
People with hypersensitivity to any ingredient of the drug. Note when using Deslora drug in the following cases:
Patients with liver failure, severe renal failure. Elderly. Pregnant and lactating women. Children under 12 years old.
2. Dosage and how to use Deslora
Since food does not affect the bioavailability of Deslora, you can take it at any time, regardless of the meal.Dosage of Deslora drug should be according to the doctor's instructions, the reference dose is as follows:
Adults and children ≥ 12 years old: Use 1 tablet x 1 time / day. Patients with liver and kidney failure: The starting dose is 1 tablet/day, every other day. In the event of an overdose of Deslora, you need to immediately remove the unabsorbed drug from the body, then symptomatic and supportive treatment is needed. In a clinical trial, desloratadine 45 mg was administered multiple times, i.e. 9 times the usual dose, but no adverse effects were observed.
If you forget a dose of Deslora, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next Deslora dose at the scheduled time. Do not take twice the prescribed dose to make up for the missed dose.
3. Side effects of the drug Deslora
Common side effects of Deslora include:Headache Dry mouth Fatigue Very rare side effects of Deslora include:
Hallucinations. Dizzy . Sleepy. Insomnia . Mentally hyperactive. Convulsions. Fast paced. Chest palpitations. Stomachache. Nausea, vomiting. Undigested. Diarrhea. Increase liver enzymes. Increased bilirubin Hepatitis. Muscle pain. Hypersensitivity reactions such as anaphylaxis, dyspnea, angioedema, pruritus, rash and urticaria. Side effects of unknown frequency with Deslora 5mg include:
QT prolongation. Jaundice. Light sensitive. Adynamia. If you experience any side effects of Deslora medicine, immediately inform your doctor or go to the nearest medical facility for timely treatment.
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