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Demencur drug belongs to the group of psychotropic drugs, indicated as adjunctive therapy in the treatment of partial seizures. Demencur is available in the form of film-coated tablets.
1. What is Demencurl?
With the main ingredient is Pregabalin (50mg or 75mg), Demencur is used to treat neuropathic pain and to support the treatment of partial seizures in adults.
What does Demencur do?
Treatment of neuropathic pain of central and peripheral origin, generalized anxiety disorder in adults. Adjunctive treatment of partial seizures with or without generalization in adults. Demencur is contraindicated in the following subjects:
People who are sensitive to Pregabalin or any of its ingredients; Women who are breastfeeding; People who often drive or operate machinery.
2. Instructions on how to take Demencur
Dosage of Demencur: From 150-600mg / day, divided into 2-3 times (Can be taken on an empty stomach or full). Specifically:
Treatment of pain of nerve origin: Take the starting dose of 150mg/day, divided into 2 or 3 times. After 3-7 days, the dose can be increased to 300mg/day depending on the level of tolerance and response. If necessary, it can be increased to 600mg (maximum dose) after the next 1 week; Treatment of epilepsy: Oral starting dose of 150mg/day, divided into 2-3 times. After 7 days, it can be increased to 300mg/day depending on the level of tolerance and response. May increase to a maximum dose of 600mg/day after the next 1 week; Treatment of generalized anxiety disorder: Oral starting dose of 150mg/day. After 7 days, it can be increased to 300mg/day depending on the level of tolerance and response. Can increase to 450mg and up to 600mg/day after 1 week. * Note:
Patients with kidney failure: Use Demencur as prescribed by your doctor; Patients with hepatic impairment: No dose adjustment is required; Children and Adolescents: There is no information available on the safety and effectiveness of Pregabalin in patients under 18 years of age. Therefore, do not use Demencur for this subject; Elderly people >65 years old: No dosage adjustment is required, unless the patient's renal function is impaired. The next treatment should be considered and re-evaluated, the patient should consult a doctor for the most accurate treatment plan.
3. Demencurl side effects
During treatment with Demencur, users may encounter the following problems:
Dizziness, drowsiness; Increased appetite; Excited, excitable mood; Erectile dysfunction, decreased sex drive; Disorientation, ataxia, abnormal coordination; Tremor, dysarthria; Memory decline ; Concentration disorder; Paresthesia, sedation; Vestibular disorders ; Edema, peripheral edema. During the treatment of neuropathic pain and epilepsy with Demencur, if you experience the above side effects or other unusual reactions, the patient should immediately notify the doctor for timely advice and support.
4. Notes when using Demencurl
In addition, conditions requiring caution when taking Demencur include:
Weight gain: Diabetic patients who gain weight while on Pregabalin treatment may require an adjustment in the dose of the hypoglycemic agent; Hypersensitivity reactions: Demencur should be discontinued immediately when signs of angioedema are observed such as: swelling of the face, swelling around the mouth or upper respiratory tract; Dizziness and drowsiness: Pregabalin ingredients can cause dizziness, drowsiness, loss of consciousness, so it is not recommended for people who often drive, do work that requires high concentration; Suicidal thoughts and behaviors: Antiepileptic drugs (including Pregabalin) often increase the risk of suicidal thoughts or behavior in patients. Therefore, when patients are taking medication, family members should be carefully monitored for signs or worsening of depression, suicidal thoughts or behavior; Drug abuse and dependence: Patients should be carefully evaluated for potential drug abuse and closely observed for signs of pregabalin abuse; Discontinuation: When pregabalin is discontinued for short-term and long-term treatment. Users may experience typical Pregabalin withdrawal symptoms such as: insomnia, headache, anxiety, nausea, profuse sweating and diarrhea. If necessary, the drug should be discontinued gradually for a minimum of 1 week; Congestive heart failure : Pregabalin should be used with caution in patients with heart failure or peripheral vascular disease ; Visual impairment : Demencur may cause transient blurred vision and other vision changes; Peripheral Angioedema: Pregabalin should be used with caution in patients with congestive heart failure; Increased creatine kinase: Pregabalin-containing drugs should be discontinued when myopathy is suspected or when creatinine kinase levels are markedly elevated; Elderly: Treatment of neuropathic pain and epilepsy with Pregabalin can cause dizziness and drowsiness, increasing the risk of accidental injury (falls) in the elderly.
5. Drug interactions Demencurl
Pregabalin component in Demencurl drug can interact with the following drugs if treated at the same time:
Increase the effect of Lorazepam and Ethanol; Aggravating cognitive and motor function impairment caused by Oxycodone; Risk of respiratory depression and coma in patients co-administering Pregabalin with other CNS depressants; Decreased function of the lower digestive system (eg, constipation, intestinal obstruction, paralytic ileus...) when used with drugs that cause constipation, typically Opioid analgesics. To avoid adverse interactions causing unwanted side effects, patients should inform their doctor, pharmacist about other drugs being used or planning to use at the same time with Demencur.
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