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Dasutam is a combination product of Terbutaline and Guaifenesin, so it is indicated for the treatment of diseases with respiratory spasms such as asthma or COPD. So how much should patients use Dasutam?
1. What is Dasutam brand-name drug?
Dasutam medicine is manufactured by Central Pharmaceutical Joint Stock Company, prepared in the form of syrup for oral use and packed in a box of 1 bottle with a volume of 75ml.
Ingredients in each bottle of Dasutam include the following ingredients:
Terbutalin sulfate content 22.5mg; Guaifenesin content 997.5mg; Some excipients have a sufficient concentration of 1 bottle of 75ml.
2. Effects of Dasutam
The effect of Dasutam is a synthesis of the main ingredients in the drug, specifically as follows:
Terbutalin sulfate: This active ingredient stimulates beta receptors of the sympathetic nervous system, thereby causing bronchial smooth muscle relaxation. and peripheral vasodilation. Thereby, Terbutaline will reduce respiratory resistance, so it helps to increase the patient's forced expiratory volume in 1 second; Guaifenesin: Stimulates airways to increase secretions to thin sputum. With the above effects of two active ingredients Terbutaline and Guaifenesin, Dasutam is indicated in the following cases:
Treatment of bronchial asthma; Chronic Obstructive Pulmonary Disease (COPD); Treatment of exacerbations of chronic bronchitis; Treatment of emphysema caused by bronchospasm is still reversible.
3. Instructions on how to use and dose Dasutam
How to use Dasutam:
Patients need to follow the manufacturer's instructions for using the drug to achieve the highest effectiveness; Dasutam is in the form of a syrup for oral use; Patients should use the syringe to receive the most accurate dose of Dasutam and can take it at any time of the day, as the effects of Dasutam are independent of meals. The recommended dosage of Dasutam is as follows:
Patients need to follow the dosage prescribed by their doctor or pharmacist; Dasutam needs to be used 2-3 times per day; Adults and children over 15 years old: Each time take 10-15ml of Dasutam syrup; Children under 3 years old: Each time take 2.5ml of Dasutam syrup; Children 3-6 years old: Each time take 2.5-5ml of Dasutam syrup; Children 7-15 years old: Each time take 5-10ml of Dasutam syrup. What to do when you miss a dose of Dasutam: The patient should take the missed dose of Dasutam as soon as he remembers. However, skip the missed dose if it is almost time for the next dose.
Dasutam overdose and treatment:
Dasutam overdose symptoms include headache, anxiety, tremors, cramps, palpitations or arrhythmias. Some patients with an overdose of Dasutam may experience a drop in blood pressure due to excessive vasodilation; Test results sometimes show hyperglycemia and lactic acidosis. Sympathomimetic beta-2 receptor agonists can cause hypokalemia due to redistribution of potassium but most do not require treatment; Treatment of Dasutam overdose: In mild to moderate cases, the dose of Dasutam should be reduced, then increased more slowly if the antispasmodic effect is not achieved. In severe cases, it is necessary to conduct gastric lavage or give the patient activated charcoal. Note the need for blood tests to check acid-base balance, blood sugar and electrolyte levels; In case of overdose of Dasutam, the heart rate and blood pressure should be monitored continuously, and changes in metabolism should be corrected in time before complications arise; In cases of Dasutam overdose and cardiac arrhythmias, cardioselective beta-blockers (eg, metoprolol) should be used.
4. Contraindications of Dasutam
Do not prescribe Dasutam to patients with a history of allergy or hypersensitivity to Terbutaline, Guaifenesin or any of the ingredients in the formulation. Concomitant use of Dasutam syrup is contraindicated in patients allergic to other sympathomimetic drugs.
5. Undesirable effects of the drug Disutam
Some possible side effects when taking Dasutam include:
Common: Increased heart rate, feeling nervous, palpitations; Changes in blood pressure; Dizziness, muscle tremors; Nervous agitation; Uncommon: Nausea, vomiting; Restlessness, trouble sleeping, or lethargy, somnolence; Headache, hot flushes; Sweating, chest tightness; Tinnitus, muscle spasms; Rare: Hypersensitivity reactions; Convulsions; Increase liver enzymes ; Vasculitis. If during the use of Dasutam any adverse effects appear, the patient should notify a qualified doctor or pharmacist for appropriate assistance.
6. Disutam . Drug Interactions
The following drugs should be paid attention to when used in combination with Dasutam, including:
Sympathomimetic stimulants: When combined with Dasutam may increase the risk of cardiovascular events; Concomitant use of Dasutam with theophylline derivatives is contraindicated; MAO, tricyclic antidepressants may increase the cardiovascular side effects of Dasutam; Halothan: Causes uterine atony, risk of bleeding, risk of severe ventricular arrhythmia when used concomitantly with Dasutam. To ensure safety and minimize adverse interactions, patients need to inform their doctor about all medications they are taking before being treated with Dasutam.
7. Some notes when using Dasutam
Caution when appointing Dasutam for the following cases:
Patients with diabetes; Hyperfunction of the thyroid gland; History of cardiovascular disease, including myocardial ischemia and arrhythmia; History of seizures; High Blood Pressure . For the treatment of asthma attacks, studies have had enough time and evidence to conclude that Terbutaline inhaled, oral, or subcutaneously is not harmful to pregnant women.
When used during pregnancy, Dasutam often makes the fetal heart rate faster, parallel to the mother's heart rate. But at birth, there are very few cases of babies with tachycardia, and blood sugar levels are also very rarely disturbed. However, if Dasutam is used during labor, the peripheral vasodilating effect of beta-2 sympathomimetic agents should be taken into account, as it may cause uterine atony.
Terbutaline is excreted in breast milk, but usually in small amounts and not sufficient to cause harm to a nursing infant. However, it is still necessary to use Dasutam with caution and weigh the benefits of treatment for the mother and the harm to the baby. If the mother wants to take Dasutam without affecting the baby, she should stop breastfeeding.
Dasutam does not affect the ability to drive and use machines, so it is recommended to use it on these subjects.
Conditions for storing Dasutam drugs:
It is necessary to store Dasutam in a dry place, the temperature is below 30 degrees Celsius; Avoid direct sunlight and keep Dasutam out of reach of children; When the drug has expired or is no longer used by the patient, it should be discarded according to the manufacturer's recommendations. Dasutam is a combination product of Terbutaline and Guaifenesin, so it is indicated for the treatment of conditions with respiratory spasms such as asthma or COPD. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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