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Daitos Inj is used to relieve the pain of surgery, trauma, toothache and joint pain. To ensure the effectiveness of using Daitos Inj medicine, users need to follow the instructions of their doctors and consult more information about the uses of Daitos Inj.
1. What are the uses of Daitos Inj?
1.1. What is Daitos Inj? Daitos Inj drug belongs to the group of analgesics, antipyretics, non-steroid anti-inflammatory drugs, drugs for the treatment of Gout and osteoarthritis.
Daitos Inj medicine includes the following ingredients:
Main active ingredient: Ketorolac tromethamine 30 mg. Excipients: Ethanol, Sodium hydroxide, Sodium Chloride, distilled water for injection. The drug is prepared in the form of a solution for injection of 1ml ampoules, box of 10 ampoules.
Daitos Inj is recommended for use by children 16 years of age and older and adults.
1.2. What are the uses of Daitos Inj? Ketorolac is a non-steroidal agent with moderate anti-inflammatory and strong analgesic effects. Widely used in the treatment of moderate to severe pain after surgery and can also be used in the treatment of acute musculoskeletal pain or anti-inflammatory in the eye. Daitos Inj is essentially a trometamol salt (tromethamine salt), which has anti-inflammatory, analgesic, and antipyretic effects, but the analgesic effect is better than the anti-inflammatory effect.
Daitos Inj is prescribed by doctors to relieve pain in moderate or severe pain such as:
Pain after surgery: abdominal, orthopedic surgery, in gynecology. Acute musculoskeletal pain such as sprains, injuries, fractures or soft tissue injuries Toothache and pain after oral surgery. Postpartum pain (but not indicated for pain relief during labor). Contraindications:
Patients with hypersensitivity to the main active ingredient Ketorolac or excipients in Daitos Inj. Patients allergic to aspirin or prostaglandin synthesis inhibitors. People with a history of stomach ulcers or gastrointestinal bleeding. Have suspected or have had a brain hemorrhage. People who are prone to bleeding, or have blood clotting disorders. Patients at high risk of bleeding or requiring surgery. The patient is on anticoagulant therapy. Patients with angioedema, nasal polyposis syndrome or bronchospasm. The patient is hypovolemic due to dehydration or any other cause. Moderate to severe decrease in kidney function. Pregnant and lactating women. Children under 16 years old
2. Usage of Daitos Inj
2.1. How to use Daitos Inj drug Daitos Inj for intramuscular or intravenous injection:
Intravenous injection must be injected slowly for at least 15 seconds. Intramuscular injection must be injected slowly, deep into the large muscles 2.2. Dosage of the drug Daitos Inj The recommended single dose is 30 mg. Or 30mg every 6 hours, up to a maximum of 120mg/day. In adults, Daitos Inj treatment lasts no more than 5 days with any route of administration. The analgesic effect of the drug begins to take effect after 30 minutes of injection, the strongest effect is about 1 to 2 hours after injection. The duration of pain relief is from 4 to 6 hours.
Elderly people, people with kidney failure and weighing < 50kg: take 1/2 of the normal dose. Treatment when missed dose:
Drugs to treat symptoms, moreover, is done by medical staff, so it is almost impossible to forget a dose.
Treatment of overdose:
Overdose of Daitos Inj can cause abdominal pain or gastrointestinal ulceration, these symptoms usually disappear after stopping the drug. The physician should carefully monitor the patient and treat the patient according to the clinical symptoms. If kidney failure is present, hemodialysis may be needed. However, hemodialysis is unlikely to completely remove ketorolac from the body after an overdose, because it has been reported in patients on hemodialysis, to have decreased creatinine clearance and prolonged half-life. ketorolac.
3. Notes when using Daitos Inj
Do not use long-term pain relievers (easy to cause stomach, intestinal, kidney complications). Do not use in obstetrics (especially pain relief during labor) will affect uterine contractions and fetal circulation. Use with caution if used in patients with renal failure (affecting drug clearance), hypertension, heart decompensation (due to possible urinary retention, edema). Use caution if you feel dizzy or drowsy while taking Daitos Inj. Do not drive, operate machinery, or perform tasks that require extreme concentration. Caution should be exercised when administering the drug to the elderly, because in these patients ketorolac is eliminated more slowly by the kidneys and they are often more sensitive to nephrotoxic or gastrointestinal adverse effects. Do not combine ketorolac with other non-steroidal anti-inflammatory drugs, with corticosteroids and also with aspirin. When treating patients with reduced renal function, moderate heart failure or liver disease, especially in the case of concomitant diuretics, the risk of fluid retention and the risk of for worse kidney function. Always remember to read the instructions for use that come with the product carefully before using it. Pay attention to check the expiry date of Daitos Inj, do not use if the product is abnormally discolored or past the expiry date or the tube is stamped or broken. Daitos Inj can be effective quickly or slowly depending on the location and body of each person.
4. Side effects of Daitos Inj
Most of Daitos Inj's adverse reactions are in the central nervous system such as dizziness, headache and somnolence. In addition, some common gastrointestinal reactions such as nausea, dyspepsia, pain and irritation. It should be noted that people treated with nonsteroidal anti-inflammatory drugs such as ketorolac may develop hyperkalemia, acute renal failure, or both. Use extreme caution in case the patient has had kidney failure before. Common:
Edema, fatigue, headache, dizziness, sweating, nausea, dyspepsia, abdominal pain, diarrhea. Uncommon:
Asthenia, pale Depression, excitement, difficulty concentrating, agitation, insomnia, paresthesia Black stools, vomiting, flatulence, stomatitis, gastric ulcer, persistent constipation , rectal bleeding Itching, urticaria, purpura Asthma, myalgia, dyspnea Frequent urination, urinary retention, oliguria Visual disturbances. Rare:
Anaphylactic reactions, including hypotension, bronchospasm, laryngeal edema, skin rash. Pulmonary edema, hallucinations of delirium, Lyell's syndrome, postoperative bleeding Stevens-Johnson syndrome, maculopapular skin rash, exfoliative dermatitis, Convulsions, hyperactivity blood, hearing loss.
5. Daitos Inj . drug interactions
Do not use Daitos Inj with drugs:
ACE inhibitors, Tacrolimus, Cyclosporine, diuretics: due to the impact on kidney function, the risk of nephrotoxicity is high. ACE inhibitors and some diuretics, including potassium-sparing diuretics: due to increased risk of hyperkalemia. Antihypertensives, including Beta-blockers, ACE inhibitors, diuretics: due to reduced antihypertensive effect. Quinolones: increased risk of convulsions. Antidiabetic sulfonylurea and Phenytoin: due to increased effects of these drugs. Drugs in the NSAID group together (including Aspirin): due to increased side effects or overdose. Corticosteroids, Bisphosphonates, Pentoxifylline, SSRIs, alcohol, Venlafaxine SNRI, Erlotinib, Iloprost, Clopidogrel ticlopidine antiplatelets, Sibutramine: May cause stomach ulcers and bleeding. Ritonavir: increases the plasma concentration of Daitos Inj. Mifepristone: due to reducing the therapeutic effect of Mifepristone. Misoprostol: increases the adverse effects of Daitos Inj. Prophylactic or therapeutic anticoagulants, such as low-dose heparin Pentoxifylline: increased risk of bleeding Probenecid: increased half-life and plasma concentrations of both drugs.
6. How to store Daitos Inj
The shelf life of Daitos Inj is 36 months from the date of manufacture. Store in a cool, dry place, away from moisture, at a temperature not exceeding 15 to 30°C, in the original packaging and out of direct sunlight. Keep out of reach of children and pets. Hopefully, with the sharing of Daitos Inj drug, it will help the patient's medication process to be effective, safe and improve the medical condition.
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