This is an automatically translated article.
Cophatrim 480 is a bactericidal and antiviral, antifungal drug with the ingredient Sulfamethoxazol. The main effect of this drug is to inhibit the synthesis of folic acid, thereby killing bacteria and viruses.1. What is Cophatrim 480?
Cophatrim 480 is a prescription medicine, used to treat bacterial infections in the body. Cophatrim 480 is prepared in the form of tablets, including two packaging specifications in boxes and bottles, with boxes of 10 x 10 tablets and bottles of 100 tablets.
In one tablet Cophatrim 480 contains Sulfamethoxazol 400 mg and Trimethoprim 80 mg; The mixture of these two drugs causes a two-stage inhibition of folic acid metabolism, thereby hindering the growth of bacteria, thereby killing bacteria.
2. What are the effects of Cophatrim 480?
Cophatrim 480 is made up of a mixture of two active ingredients, Sulfamethoxazol 400 mg and Trimethoprim 80 mg and other excipients, just enough for one tablet. This is a group of anti-parasitic, anti-infective and anti-viral drugs. The drug with the effect of being a broad-spectrum treatment with infections such as urinary tract infections, respiratory tract infections, bacillus dysentery,...Sulfamethoxazol has a molecular structure similar to aminobenzoic acid. Once in the body, Sulfamethoxazol binds to dihydropteroate synthetase instead of aminobenzoic acid, causing the first stage inhibition of folic acid synthesis in bacteria.
The effects of Cophatrim 480 include:
Treatment with a broad spectrum of antibacterial activity against gram-negative and gram-positive aerobic bacteria such as: Staphylococcus, E.coli, Enterobacter, Proteus indol positive, Klebsiella,... Article Treatment for patients with bacterial and viral infections: gonococcal infection, urinary tract infection, urinary tract infection, bacillus dysentery, infectious prostatitis, ...
3. How to use Cophatrim 480
3.1. How to use Cophatrim 480 Patients should use the drug orally. Swallow Cophatrim 480 tablets whole with an appropriate amount of liquid, such as cooled boiled water. Patients should not alter the state of the drug, such as breaking, chewing, or crushing the drug, as these actions may result in a loss of the pharmacodynamics of the product.
Follow and use according to the recommended dose and prescribed by the doctor, absolutely do not adjust the dose of oral medication by yourself.
3.2. Dosage of Cophatrim 480 Used to treat respiratory tract infections: Chronic bronchitis : Adults use 2 to 3 tablets, each time, twice a day.
Acute otitis media and acute pneumonia in children: The recommended dose for children depends on the weight of this subject. Please consult your doctor for further advice.
Treatment of urinary tract infections: Treatment of uncomplicated urinary tract infections: Patients use 2 tablets once, twice daily for 10 days. Or can use 1 tablet per day for a period of 4 days.
Treatment of chronic recurrent urinary tract infections: take from half a tablet, consider double or quadruple dose and take 1 to 2 times per week
Each patient with different pathology will have different dosage and own usage. Therefore, ask your doctor about the dosage of Cophatrim before taking it.
3.3. Treatment when forgetting, overdosing Missed dose: Patients should take Cophatrim 480 as soon as they remember. But if it's almost time for your next dose to remember, take it as usual and skip the missed dose. Do not take a double dose of Cophatrim 480 to make up for the missed dose.
Overdose: Symptoms of Cophatrim 480 overdose have been recorded including: loss of appetite, nausea, headache and more seriously can cause unconsciousness. Patients may have hematopoietic disorders and jaundice: these are two late manifestations of Cophatrim overdose.
In case of overdose symptoms, treat symptomatically, such as induce vomiting, gastric lavage; Acidification of urine to increase elimination of Trimethoprim.
3.4. Contraindications Cophatrim 480 Absolutely not used with patients:
Hypersensitivity or irritation to Sulfamethoxazol, Trimethoprim or any other drug or ingredient in the drug. Patients with severe renal impairment for whom drug levels cannot be monitored, because drug concentrations in urine are 150 times higher than in serum. Patients with severe folic acid deficiency causing erythroblastic anemia Do not use for infants under 2 months of age Women are breast-feeding.
4. Notes when using Cophatrim 480
4.1 Side effects of Cophatrim 480 Cophatrim 480 will cause some unwanted side effects on the organ systems in the body. Side effects of Cophatrim include: nausea, diarrhea, Stevens Johnson and Lyell syndrome, or causing a lack of cells in the blood such as white blood cells and platelets, lack of folate in the body.
4.2 Cophatrim 480 Drug Interactions Cophatrim 480 is not recommended to be co-administered with diuretics, because it may cause thrombocytopenia in the elderly.
Do not use together Sulfamethoxazol with drugs that help eliminate methotrexate, because it can reduce elimination and increase the effect of methotrexate.
Caution should be exercised when pyrimethamine 25 mg/week is co-administered with Cophatrim 480, as it may increase the risk of megaloblastic anemia.
Inhibits phenytoin metabolism in the liver, increases the effect of phenytoin.
The patient tells the medical history and the drugs he is taking and taking in the previous 3 months to the treating doctor to make a decision whether to use Cophatrim 480 with other drugs or not.
4.3 Storing Cophatrim 480 Medicines Store Cophatrim 480 in a dry, well-ventilated place, in the original packaging of the manufacturer, protected from light.
The appropriate storage temperature for Cophatrim 480 is from 15 to under 30 degrees Celsius
Cophatrim 480 should not be used after the expiry date printed on the package.
Keep medicine out of reach of children and pets.
Hope the article has helped you know more about the use and dosage of Cophatrim 480. This is a prescription medication that treats bacterial infections. Read the instructions carefully and follow the instructions of your doctor when using.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
