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Codalgin forte is a non-steroidal anti-inflammatory drug (NSAIDS), which relieves mild to moderate pain, and reduces fever when the fever is over 39 degrees, in addition to helping to relieve cough, sedation, and sleep. So how should Codalgin forte be used?1. What is Codalgin forte?
Codalgin forte is a drug belonging to the group of non-steroidal anti-inflammatory drugs (NSAIDS), containing 2 main ingredients including: Paracetamol 500mg content has analgesic, antipyretic effects, no anti-inflammatory effect. Pain relief is due to the inhibition of COX enzyme, which inhibits the conversion of arachidonic acid into prostaglandin, an inflammatory substance; and because of its ability to inhibit the transmission of pain nerve impulses from the peripheral nerves to the central nervous system. Antipyretic is due to its ability to inhibit the hypothalamic thermoregulatory center causing peripheral vasodilation. Codeine phosphate belongs to the group of opioid analgesics, a derivative of morphine, which has analgesic effect by inhibiting the transmission of pain sensation nerve impulses from the CNS to the CNS. In addition, there are sedative effects causing sleep, dependence when used for a long time and withdrawal syndrome when stopping use, reducing intestinal motility, constipation, respiratory depression. In general, Codalgin forte 500mg + 30mg has the effect of relieving mild to moderate pain such as rheumatoid arthritis, sore throat, headache; reduce fever in cases of fever over 39 degrees due to earache, migraine; increase the body's pain threshold; In addition, it also helps to reduce cough, sedation, induce sleep but very little.2. How to use, dose of Codalgin forte
Codalgin forte drug has a tablet form, used orally, after eating. Dosage varies according to age;
Adults, children over 12 years old take 1-2 tablets / time, repeat at least after 4 hours, not more than 8 tablets / day. Children 7-12 years old take 1⁄2 tablets / time, repeat at least after 4 hours, not more than 3 tablets / day. Do not give the medicine to children under 7 years old
3. Codalgin forte . side effects
Side effects of Codalgin forte are side effects when overdose of paracetamol and codeine phosphate, they include:
Paracetamol in high doses can cause stomach complications, acute liver failure, allergies, rash, leukopenia neutropenia, thrombocytopenia, shock, fatigue. High doses of codeine phosphate can cause drowsiness, euphoria, dependence when used for a long time, in addition to constipation and respiratory depression.
4. Contraindications Codalgin forte
Codalgin forte is contraindicated in subjects allergic to drug ingredients, people with liver diseases such as hepatitis, liver failure, cirrhosis, people with severe renal impairment, alcoholics, G6PD deficiency , people with abdominal pain of unknown cause.5. Caution when using Codalgin forte
During the use of Codalgin forte, it is necessary to adhere to the correct dosage and time of taking the drug, not to abuse the drug to avoid side effects including drug abuse.
Subjects that need to be cautious in the course of drug use include people:
Severe liver and kidney failure, viral hepatitis Brain damage caused by codeine causes respiratory depression, which can cause respiratory failure and increased complications. Intracranial pressure Heart failure, respiratory failure, respiratory diseases, patients with asthma, chronic obstructive pulmonary disease History of epilepsy or high fever Not recommended for women pregnancy and lactation, because the drug has the ability to cross the placental barrier and the mammary epithelial cell barrier The elderly are very sensitive to the main and side effects of the drug, the elderly body tolerates the drug poor and the mechanism of regulation of homeostasis is reduced, therefore, frequent monitoring and dose adjustment as necessary.
6. Codalgin forte . drug interactions
The risk of side effects is higher when Codalgin forte is used in combination with the following drugs:
Drugs with CNS depressants such as diazepam, phenobarbital Drugs that increase hepatic metabolism such as phenobarbital, carbamazepine , rifampicin Opioid analgesics Other drugs in the composition contain paracetamol In addition, during drug use, it is necessary to avoid drinking alcohol and alcoholic beverages to limit the risk of liver damage.
If in the process of taking the drug, the patient has more questions or problems, it is necessary to discuss with the doctor for examination and appropriate indications.
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