Uses of Clotrimark cream

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1. What is Clotrimark cream?

What is Clotrimark cream? The drug Clotrimark cream contains the main ingredient is Clotrimazole 1% and excipients just enough provided by the manufacturer. The drug is prepared in the form of a skin cream, packaged in a box of 1 tube of 15g.
Mechanism of action of the drug Clotrimark cream:
The drug has broad-spectrum antifungal properties, capable of inhibiting the growth of most pathogenic fungi such as dermatophytes, yeasts and Malassezia furfur. Interferes with membrane lipids by affecting the permeability of the fungal cell wall. At therapeutic doses, the drug inhibits cell wall ergosterol synthesis, but at higher concentrations it has an additional mechanism of membrane damage that has nothing to do with sterol synthesis.

2. Uses of Clotrimark cream

Clotrimark cream is indicated for the treatment of the following cases:
Topical treatment of tinea pedis (dermatophytosis, interstitial fungus), tinea cruris (inguinal fungus), tinea corporis (dermatophytosis, strabismus) by T.rubrum, T. Mentagrophytes, E.floccosum and M.canis. Treatment of fungal skin diseases caused by Candida such as C.albicans and tinea versicolor caused by M.furfur. In some cases of non-fungal skin infections such as erythrasma caused by Corynebacterium minutissimum, the drug also has a positive effect in the treatment. Clotrimark cream is contraindicated in patients allergic to topical clotrimazole or imidazole.

3. Dosage and how to use Clotrimark cream

Clotrimark cream is used twice a day, morning and night, continuously for 1 month or at least 2 weeks when symptoms are gone to prevent recurrence. Clotrimark cream is made in the form of a cream, so it should be used on the skin. Patients need to wash the affected skin area to be applied the medicine, apply a thin layer, rub gently at the diseased skin and spread around 2cm. When applying the medicine, avoid scratching the affected skin. It is necessary to keep the diseased area clean and dry, combined with personal and environmental hygiene to avoid recurrence of the disease and new sources of infection. Clinical symptoms such as pruritus usually improve within the first week. However, the patient should not stop taking the drug until the course is over. If after 4 weeks of taking the drug, the symptoms do not improve, the diagnosis should be reviewed and the therapy may be changed. Discontinue use if skin condition is severe. With diseased skin areas with blood, pus, dirty fluid, and scales, it is necessary to clean before applying the medicine and avoid using gauze to cover the area due to the risk of producing anaerobic bacteria, making the diseased skin worse.

4. Side effects of Clotrimark cream

When using Clotrimark, patients may have unwanted effects such as redness, stinging sensation, blisters, peeling skin, edema, itching, urticaria, burning sensation, skin irritation all over the body. , especially when applied to open wounds and overdosed as directed.
If the side effects do not improve, it is necessary to stop the drug and tell the doctor or pharmacist whether to continue or use an alternative therapy is essential.

5. Clotrimark cream drug interactions

Please list and tell your doctor about all the medicines you are taking to avoid possible harmful interactions when taking different drugs together. Drugs that may interact with Clotrimark cream such as:
Antagonistic effects between imidazoles (including clotrimazole) and polyene antibiotics in vitro have been reported. Probably because imidazole inhibits ergosterol synthesis while polyene antibiotics exert their antifungal action by binding to cell membrane steroids. The effect of clotrimazole on liver mitochondrial enzymes is not a problem for topical formulations.

6. Some notes when using Clotrimark cream

While using Clotrimark cream, patients should pay attention:
The drug is only for external use, avoid contact with eyes. In case of contact with eyes, rinse immediately with water. In case of eye irritation, the patient should be taken to the Hospital for timely appropriate intervention. In the course of taking the drug, if the patient has an allergic or sensitive reaction, the doctor or pharmacist should be consulted for more information to stop treatment with Clotrimark cream and change to another therapy. Pregnant women: In clinical studies, using Clotrimark cream for vaginal application to pregnant women for 3 months or more, clinical observations did not occur unwanted effects. However, it is important to have a clear indication from the doctor that the benefits of taking the drug outweigh the risks in the first 3 months of pregnancy and to avoid large-scale application. Lactation: It is not known whether Clotrimark cream is excreted in breast milk, so caution should be exercised when using the drug in this group of subjects. Above is the important information of Clotrimark cream, carefully reading the instructions before use and strictly following the doctor's instructions will bring the best treatment results to the patient.
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