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Clopidogrel Al 75mg belongs to the group of cardiovascular drugs, effective in the prevention of thromboembolic disorders such as myocardial infarction, stroke, and peripheral artery disease. So what is Clopidogrel Al 75mg and in what cases is it indicated?1. What is Clopidogrel Al 75mg?
Clopidogrel Al drug whose main ingredient is Clopidogrel is prepared in the form of Clopidogrel bisulfate 75mg and other excipients such as lactose monohydrate, corn starch, povidone k30, red iron cooxide, titanium dioxide, tAlc, colloidAl anhydrous silica just enough for 1 tablet .
The drug is prepared in the form of round tablets, pink film-coated, two meniscus, one smooth side, one side engraved with number 75. The drug is packed in box, each box contains 3 blisters x 10 tablets.
2. Uses of Clopidogrel Al 75mg
Prevention of arterial thrombotic events Used in adult patients with myocardial infarction (from a few days to less than 35 days), ischemic stroke (from 7 days to less than 6 months) ) or established peripheral artery disease. Adults with acute coronary syndromes: Acute coronary syndromes presenting with unstable angina or non-Q-wave myocardial infarction, including patients with stents (coronary stents) during percutaneous coronary intervention, used in combination with aspirin. Acute ST-segment elevation myocardial infarction in combination with aspirin in medically eligible patients for thrombolytic therapy. Prevention of possible arterial thrombotic and thromboembolic events in atrial fibrillation For adult patients with atrial fibrillation with at least one risk factor for vascular events, not suitable for In patients with vitamin K antagonists (VKAs) and at low bleeding risk, clopidogrel is indicated in combination with aspirin for the prevention of arterial thrombotic and thromboembolic events, including stroke. Some cases are contraindicated to use Clopidogrel Al
People with hypersensitivity to the active ingredient clopidogrel or any of its ingredients. People who are having pathological bleeding such as peptic ulcer, intracranial hemorrhage. The patient has severe liver failure.
3. Usage and dosage of Clopidogrel Al 75mg
3.1 How to take Clopidogrel Al is a film-coated tablet that should be taken orally. Patients need to take the medicine with a sufficient amount of water. The duration of use of the drug does not depend on the meal.
3.2 Dosage Users should use according to the doctor's prescription or can refer to the following dosage:
For adults and the elderly: Use the usual dose with a single dose of 75mg/day. For patients with acute coronary syndromes: Acute coronary syndromes without ST segment elevation (unstable angina or non-Q-wave myocardial infarction): a loading dose should be initiated. : 300mg/time only and then continue with a dose of 75mg x 1 time/day (in combination with aspirin 75 - 325 mg/day). Because the higher the aspirin dose, the greater the risk of bleeding, so do not take aspirin in doses exceeding 100 mg. Acute ST-segment elevation myocardial infarction with a single loading dose of 300 mg (in combination with aspirin), followed by a single dose of 76 mg/day. Note: In patients over 75 years of age do not use loading dose at the beginning of treatment. For patients with atrial fibrillation: a single dose of 75 mg/day.
4. Side effects of Clopidogrel Al 75
Like other drugs, when using Clopidogrel Al 75, users may experience some side effects with the following drugs:
Common reactions: Causes hematoma, diarrhea, dyspepsia, abdominal pain, discharge gastrointestinal bleeding, bruising Uncommon reactions: decrease in platelets and white blood cells, headache, paresthesia, dizziness, intracranial hemorrhage, in some cases fatal , peptic ulcer disease, gastritis, constipation, flatulence, nausea... Rare reactions: neutropenia, including severe neutropenia, causing retroperitoneal hemorrhage ... Note : When seeing the appearance of symptoms on suspicion of drug use, users need to stop the drug and notify the treating doctor to get timely and necessary treatment information.
5. Clopidogrel Al 75mg drug interactions
Some interactions with Clopidogrel Al:
Cilostazol: Potentially inhibiting platelet aggregation, careful monitoring of the patient's bleeding during the use of two drugs at the same time. Non-Steroidal Anti-Inflammatory Drugs, Warfarin: Potentially increases the risk of bleeding in users, so caution should be taken. With proton pump inhibitors: decreased plasma concentrations of the active metabolite of clopidogrel and decreased antiplatelet effects Concomitant use with drugs such as omeprazole inhibitors of CYP2C19: reduced clinical efficacy Clopidogrel sieve.
6. Some notes when using Clopidogrel Al 75mg
When using the drug, be careful with the following cases:
Patients are at risk of bleeding due to trauma, surgery or some other bleeding diseases. The drug should be discontinued 7 days before surgery. When the patient takes the drug longer than usual, it is necessary to stop taking the drug as soon as there is abnormal bleeding and notify the treating doctor immediately. Caution should be exercised when using Clopidogrel Al in patients with renal or hepatic impairment. The drug does not affect the patient while driving a vehicle or operating machinery. No studies on the effects of the drug have been conducted on pregnant women, so only use them when absolutely necessary. At the same time, it is necessary to consider stopping the drug during breastfeeding, to avoid affecting the baby. Hopefully, the information shared about the uses, usage and some necessary notes about the drug Clopidogrel Al 75mg will help users understand more details and achieve the best effect when used.
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