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Cinatropyl contains 2 main ingredients, Piracetam 400mg and Cinnarizine 25mg. Belonging to a group of psychotropic drugs, it is used to treat stroke, post-traumatic brain weakness and arterial hypertension.
1. What is cinatropyl?
Cinatropyl is prescribed by doctors for patients to use to treat diseases such as:
Chronic cerebral vascular insufficiency due to atherosclerosis and arterial hypertension. Stroke and post-stroke due to ischemic stroke in the brain and patients with vascular dystonia. Brain damage after trauma. Treatment of encephalopathy caused by psycho-organism syndromes, disorders of memory and other cognitive functions such as disturbances of emotions and desires. Labyrinthine pathology such as dizziness, tinnitus, nausea and nystagmus. Meniere's syndrome. Used in the prevention of pain in movement and migraine. Helps improve cognitive processes for children with mental retardation. Contraindications:
Do not use with patients who are sensitive to the ingredients of Cinatropyl. Patients with liver failure, severe renal failure with creatinine level less than 20ml/min. People with Huntington's disease. Patients with porphyria.
2. Dosage and usage
How to use: Cinatropyl is prepared in the form of tablets to be used after meals. The duration of use of the drug should not exceed 3 months.
Dosage :
For adults use 1-2 tablets, take 3 times a day for a period of 1-3 months With children take 1-2 tablets, take 1-2 times a day. For patients with renal impairment, the dose should be adjusted accordingly or the interval between doses should be increased depending on creatinine clearance and serum creatinine concentration.
Creatinine clearance less than 60 ml/min or when serum creatinine is above 1.25 mg/100 ml, dose adjustment is required:
Creatinine clearance is 60-40 ml/min, serum creatinine is 1, 25-1//ml (half-life of piracetam is more than twice as long): Only half of the normal dose should be used. Creatinine clearance is 40-20 ml/min, serum creatinine is 1/7-3 ml (half-life of piracetam is 25-42 hours): Only 1/4 of the normal dose should be used.
3. Unwanted side effects
Common side effects of Cinatropyl:
Central nervous system: Somnolence; Systemic effects: Body weakness; Gastrointestinal reactions: Nausea, vomiting, diarrhea, abdominal pain, abdominal distension; Nervous: Feeling restless, excitable mood, headache. Uncommon side effects of Cinatropyl :
Body as a whole: Dizziness; Nervous system: Tremors and headaches; Digestion: Feeling dry mouth, body weight gain; Other reactions such as sweating, allergic reactions. Rare side effects of Cinatropyl:
Central nervous system: Extrapyramidal symptoms in the elderly or during long-term treatment. Cardiovascular: Lowers blood pressure (if high doses are used).
4. Precautions while using Cinatropyl
Cinarizin causes epigastric pain. Therefore, patients should take Cinatropyl after meals to reduce stomach irritation. Cinarizin causes somnolence, especially at the beginning of treatment. Therefore, patients should avoid jobs that require alertness. Avoid long-term use in the elderly because the drug can increase or develop extrapyramidal syndrome, sometimes with depressive symptoms. Cinatropyl should be used with caution in patients with renal impairment because piracetam is excreted by the kidneys, so the rate of elimination of the drug is fast or slow depending on the degree of renal impairment and creatinine clearance. Users should monitor kidney function regularly, especially people with kidney failure and the elderly. Pregnant and lactating women: Cinatropyl drug penetrates the placenta and can be excreted in breast milk, affecting the development of young children, so doctors recommend not to use the drug for pregnant women and children. suck.
5. Cinatropyl drug interactions
Drug interactions can reduce the effectiveness or increase unwanted side effects of Cinatropyl . Therefore, the patient needs to inform the doctor or pharmacist of the drugs that they are currently using to prescribe more effectively. Some drugs when used together with Cinatropyl may encounter interactions such as:
Piracetam and thyroid essence: When these two drugs are used together, they cause reactions such as lack of clarity of mind, irritability. and sleep disturbances. Alcohol, tricyclic antidepressants: Concomitant use increases the sedative effect of cinnarizine.. The article provides information on what Cinatropyl is, dosage and precautions for use. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Cinatropyl exactly as directed by your doctor. Store Cinatropyl in a cool, dry place at a temperature not exceeding 30 degrees Celsius and out of the reach of small children.
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